Felix Wunderlich

Felix Wunderlich


Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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10 June 2022 in Knee Surgery, Sports Traumatology, Arthroscopy
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Journal Article
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FWFelix Wunderlich
Felix Wunderlich
LELukas Eckhard
Lukas Eckhard
MBMatthias Büttner
Matthias Büttner
TLToni Lange
Toni Lange
JKJürgen Konradi
Jürgen Konradi
JLJörg Lützner
Jörg Lützner
Purpose: Post‐operative outcome after total knee arthroplasty (TKA) in the treatment of end‐stage osteoarthritis correlates strongly with pre‐operative impairment‐driven patient treatment goals. However, a clinical tool for measuring patient treatment goals in correlation to impairments is still missing, which impedes patient‐oriented indication in TKA.Methods: Patients scheduled for TKA were recruited in four German hospitals. All patients were handed the INDICATE Knee Score pre‐operatively. The score contains 31 treatment goals with respective impairments, subdivided into seven categories. They were asked to rank all treatment goals and impairments on a 3‐point scale. Treatment goals and impairments were then checked for frequency of occurrence. Correlation of goal and impairment was tested. Analysis for associations of treatment goals and different cohort characteristics (age, sex, BMI) was conducted.Results: 1.298 patients were included in the study. Seven treatment goals were categorised as “main goal” from more than 90% of all patients (“knee pain”, “range of motion”, “walking distance”, “overall physical function”, “climbing stairs”, “quality of life”, “implant survival”). Comparing age groups, there were significant associations towards higher expectations regarding working, physical and sports related treatment goals in younger patients (< 65y) (“ability to work” (P ≤ .001), “sports activities” (P ≤ .001), “sex life” (P ≤ .001), “dependence on help of others” (P = .015), “preventing secondary impairment” (P = .03), “dependence on walking aids” (P = .005)). Higher BMI resulted in increasing relevance of “weight reduction” (P ≤ .001), “climbing stairs” (P = .039) “global health status” (P = .015) and “long standing” (P = .007) as a “main goal”. Analysis for differences in treatment goals regarding sex showed women choosing more treatment goals as “main goals” than men.Conclusion: Seven treatment goals which were expected by > 90% in our collective can be classified as general treatment goals for TKA. Demographic factors (age, sex, BMI) were significantly associated with patients’ expectations for TKA. We conclude physicians should clearly assess their patients’ demands prior to TKA to maximise post‐operative outcome.Level of evidence: Prognostic Level III.

5 May 2023 in Knee Surgery, Sports Traumatology, Arthroscopy
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Journal Article
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FWFelix Wunderlich
Felix Wunderlich
JKJasmin Ghaemi Kerahrodi
Jasmin Ghaemi Kerahrodi
RKRobert Kuchen
Robert Kuchen
TKThomas Klonschinski
Thomas Klonschinski
YAYama Afghanyar
Yama Afghanyar
LELukas Eckhard
Lukas Eckhard
Purpose: Personality traits, such as dispositional optimism and pessimism, have impact on a variety of health‐related problems. Influence on outcome in total knee arthroplasty (TKA) could only be shown for other personality trait concepts, but not for dispositional optimism/pessimism. This study aims to examine the association of dispositional optimism/pessimism with pre‐operative joint function and post‐operative outcome in TKA.Methods: Data were acquired in a multicentre, cross‐sectoral, prospective study (the PROMISE Trial). Patients were followed for 12 months post‐operatively. Dispositional optimism/pessimism was measured pre‐operatively via the revised Life Orientation Test (LOT‐R), pre‐ and post‐operative function was measured via the 12 Item Knee‐osteoarthritis outcome Scores (KOOS‐12). Log‐linear regression models considering known confounders and t‐test were carried out to show the association of LOT‐R scores with pre‐ and post‐operative KOOS‐12 scores.Results: 740 patients were analyzed. Optimistic LOT‐R was significantly positively associated to the mean scores of KOOS‐12 pre‐ and post‐operative, while pessimistic LOT‐R was significantly associated negatively (pre‐operative: optimistic p = 0.001, pessimistic p = 0.001; post‐operative optimistic: 3M p = 0.001, 6M p = 0.001, 12M p = 0.001; post‐operative pessimistic: 3M p = 0.01, 6M p = 0.004, 12M p = 0.001).Conclusion: Optimism was positively associated with pre‐operative joint function and, more importantly, post‐operative functional outcome in TKA, while pessimism was associated with the opposite. Assessing patients’ general personality traits prior to surgery to identify pessimistic patients, hence being at risk for poor outcome in TKA, should be considered to react to the patients’ special needs and possible pessimistic expectations, i.e., through a cognitive–behavioral intervention, to potentially increase optimism and hereby post‐operative outcome in TKA.Level of evidence: Prognostic Level III.

Verified
Journal Article
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FWFelix Wunderlich
Felix Wunderlich
MAMaheen Azad
Maheen Azad
RWRuben Westphal
Ruben Westphal
TKThomas Klonschinski
Thomas Klonschinski
PBPatrick Belikan
Patrick Belikan
LELukas Eckhard
Lukas Eckhard
Neutral coronal leg alignment is known to be important for postoperative outcome in total knee arthroplasty (TKA). Customized individually made implants (CIM) instrumented with patient-specific cutting guides are an innovation aiming to increase the precision and reliability of implant positioning and reconstruction of leg alignment. We aimed to compare reconstruction of the hip–knee–ankle angle (HKA) of the novel CIM system iTotal™ CR G2 (ConforMIS Inc.) to a matched cohort of the off-the-shelf (OTS) knee replacement system Vanguard™ CR (Zimmer Biomet). Retrospective analysis of postoperative coronal full-leg weight-bearing radiographs of 562 TKA (283 CIM TKA, 279 OTS TKA) was conducted. Via a medical planning software, HKA and rotation of the leg were measured in postoperative radiographs. HKA was then adjusted for rotational error, and 180° ± 3° varus/valgus was defined as the target zone HKA. Corrected postoperative HKA in the CIM group was 179.0° ± 2.8° and 179.2° ± 3.1° in the OTS group (p = 0.34). The rate of outliers, outside of the ±3° target zone, was equal in both groups (32.9%). Our analysis showed that TKA using patient-specific cutting guides and implants and OTS TKA implanted with conventional instrumentation resulted in equally satisfying restoration of the coronal leg alignment with less scattering in the CIM group.

Verified
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PSPhilipp Schippers
Philipp Schippers
VBVictoria Buschmann
Victoria Buschmann
FWFelix Wunderlich
Felix Wunderlich
YAYama Afghanyar
Yama Afghanyar
Sebastian FischerSebastian Fischer
Sebastian Fischer
LELukas Eckhard
Lukas Eckhard
Background: Bucket-handle meniscal tears are mostly treated arthroscopically. However, there is no clear evidence as to whether the time to surgery impacts the outcome and whether or not lesions should be treated urgently. Methods: Sixty patients were interviewed about the current status of their knee with a mean follow-up of 6.1 years (SD = 3.5). Forty-one patients underwent meniscus repair, and fifteen patients received partial resections. The primary outcome was the rate of reoperation after meniscus repair. Secondary outcomes were pain at rest and during exercise, return to sports, and Tegner and Lysholm scores. Results: The average time to surgery was 14.4 days, with no significant impact of surgical timing on the rate of reoperation. Furthermore, no significant differences were found in pain levels, return to sports, or Tegner and Lysholm scores based on the timing of surgery. Conclusions: In our cohort, the time to surgery was not a prognostic factor for the reoperation rate or postoperative outcome in repairing bucket-handle meniscal tears. Therefore, arthroscopic repair should not be performed in an emergency setting but conducted after careful planning by experienced arthroscopy surgeons. Regarding the return to sports, postoperative factors such as rehabilitation protocols or surgical techniques could be more important than the time to surgery.

Verified
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PSPhilipp Schippers
Philipp Schippers
PDPhilipp Drees
Philipp Drees
EGErol Gercek
Erol Gercek
FWFelix Wunderlich
Felix Wunderlich
DMDaniel Müller
Daniel Müller
Sebastian FischerSebastian Fischer
Sebastian Fischer
“Normal” and “abnormal” are frequently used in surgical planning and to evaluate surgical results of the forefoot. However, there is no objectifiable value of metatarsophalangeal angles (MTPAs) 2–5 in the dorsoplantar (DP) view with which to objectively evaluate lesser toe alignment. We aimed to determine which angles are considered to be “normal” by orthopedic surgeons and radiologists. Thirty anonymized radiographs of feet were submitted twice in randomized order to determine the respective MTPAs 2–5. After six weeks, the anonymized radiographs and photographs of the same feet without apparent affiliation were presented again. The terms “normal,” “borderline normal,” and “abnormal” were assigned by the observers. Viewers considered MTP-2 alignment from 0° to −20° to be normal, and below −30° abnormal; MTP-3, 0° to −15° to be normal and below −30° abnormal; MTP-4, 0° to −10° normal and below −20° abnormal. Between 5° valgus and 15° varus was the range of MTP-5 recognized as normal. High intra-observer but low interobserver reliability with overall low correlation of clinical and radiographic aspects was observed. The assessment of the terms “normal” or “abnormal” are subject to a high degree of variation. Therefore, these terms should be used cautiously.

26 September 2024 in Archives of orthopaedic and trauma surgery
Verified
Journal Article
Open access
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MBMatthias Büttner
Matthias Büttner
FWFelix Wunderlich
Felix Wunderlich
PDPhilipp Drees
Philipp Drees
YAYama Afghanyar
Yama Afghanyar
SFSebastian Fischer
Sebastian Fischer
LELukas Eckhard
Lukas Eckhard
Introduction: To consider the inherent respondent burden of PROMs, the HOOS-12 as a shortform of the well-established HOOS questionnaire has been published. While the HOOS-12 has been validated in an initial study, further evaluation in other, non-English speaking cohorts is necessary. We therefore aimed to evaluate responsiveness, convergent construct validity, internal consistency, and floor and ceiling effects of the HOOS-12 in a cross-sectoral german cohort. Materials and Methods: European Quality of Life 5 Dimensions scores and HOOS data of patients undergoing total hip arthroplasty (THA) were used for the analyses. HOOS-12 scores were calculated from the full length HOOS. Statistical analysis was conducted, investigating internal consistency, floor and ceiling effects, convergent and discriminant validity, responsiveness, and known-group comparisons. Results: A ceiling effect was present for postoperative HOOS-12 score and its pain, function and QoL subscales. Internal consistency was high between baseline and all follow ups, inter-item correlation was high (Cronbach’s alpha > 0.30) for HOOS-12 score and all subscales. Correlation of HOOS-12 pain with HOOS pain was high (r = 0.9). Correlation of HOOS-12 function with HOOS ADL and HOOS S/R was high (r = 0.89, r = 0.74). Correlation was moderate between HOOS-12 pain and HOOS-12 function with its respective EQ-5D score (r=-0.58, r=-0.59). Conclusion: The HOOS-12 showed good convergent construct validity and is responsive to changes in pain, function, QoL and hip impact between preoperatively and 1 year postoperatively. A substantial ceiling effect for all subscales at 1 year postoperatively limits the ability to capture variance across particularly well performing patients. Trial Registration: The Trial is registered with the German Clinical Trials Register (https://www.drks.de; DRKS00013972; 23 March 23, 2018).