Go Tajima

Dr. Go Tajima

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Research Focus & Metrics

Academic Career Length

22Years (2005-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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Verified
Journal Article
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YSYosuke Shigematsu
Yosuke Shigematsu
MYMiori Yuasa
Miori Yuasa
NINobuyuki Ishige
Nobuyuki Ishige
HNHideki Nakajima
Hideki Nakajima
GTGo Tajima
Go Tajima
To minimize false-positive cases in newborn screening by tandem mass spectrometry in Japan, practical second-tier liquid chromatography-tandem mass spectrometry analyses have been developed using a multimode ODS column with a single set of mobile phases and different gradient elution programs specific to the analysis of acylcarnitines, acylglycines, amino acids, and organic acids. Most analyses were performed using underivatized samples, except for analysis of methylcitric acid, and careful conditioning of the column was necessary for analyses of organic acids. Our second-tier tests enabled us to measure many metabolites useful for detection of target disorders, including allo-isoleucine, homocysteine, methylmalonic acid, and methylcitric acid. We found that accumulation of 3-hydroxyglutaric acid was specific to glutaric acidemia type I and that the ratio of 3-hydroxyisovaleric acid to 3-hydroxyisovalerylcarnitine was useful to detect newborns of mothers with 3-methylcrotonyl-CoA carboxylase deficiency. Data from the analysis of short-chain acylcarnitine and acylglycine were useful for differential diagnosis in cases positive for C5-OH-acylcarnitine or C5-acylcarnitine.


1 December 2016 in Molecular Genetics and Metabolism
Verified
Journal Article
Closed access
GTGo Tajima
Go Tajima
KHKeiichi Hara
Keiichi Hara
MTMiyuki Tsumura
Miyuki Tsumura
RKReiko Kagawa
Reiko Kagawa
SOSatoshi Okada
Satoshi Okada
MKMasao Kobayashi
Masao Kobayashi

4 December 2018 in Journal of Human Genetics
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Journal Article
Closed access
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GTGo Tajima
Go Tajima
KHKeiichi Hara
Keiichi Hara
MYMiori Yuasa
Miori Yuasa

19 July 2005 in Journal of Chromatography B
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Journal Article
Closed access
GTGo Tajima
Go Tajima
NSNobuo Sakura
Nobuo Sakura
HYHiroko Yofune
Hiroko Yofune
YNYutaka Nishimura
Yutaka Nishimura
HOHiroaki Ono
Hiroaki Ono
MKMasao Kobayashi
Masao Kobayashi