Stefan Niehues

Prof. Dr. Stefan Niehues

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Research Focus & Metrics

Academic Career Length

23Years (2004-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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24 June 2020 in Diagnostics
Verified
Journal Article
Open access
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MEMichael Endres
Michael Endres
FHFlorian Hillen
Florian Hillen
MSMarios Salloumis
Marios Salloumis
Ahmad SedaghatAhmad Sedaghat
Ahmad Sedaghat
SNStefan Niehues
Stefan Niehues
RGRobert Gaudin
Robert Gaudin
Periapical radiolucencies, which can be detected on panoramic radiographs, are one of the most common radiographic findings in dentistry and have a differential diagnosis including infections, granuloma, cysts and tumors. In this study, we seek to investigate the ability with which 24 oral and maxillofacial (OMF) surgeons assess the presence of periapical lucencies on panoramic radiographs, and we compare these findings to the performance of a predictive deep learning algorithm that we have developed using a curated data set of 2902 de-identified panoramic radiographs. The mean diagnostic positive predictive value (PPV) of OMF surgeons based on their assessment of panoramic radiographic images was 0.69 (±0.13), indicating that dentists on average falsely diagnose 31% of cases as radiolucencies. However, the mean diagnostic true positive rate (TPR) was 0.51 (±0.14), indicating that on average 49% of all radiolucencies were missed. We demonstrate that the deep learning algorithm achieves a better performance than 14 of 24 OMF surgeons within the cohort, exhibiting an average precision of 0.60 (±0.04), and an F1 score of 0.58 (±0.04) corresponding to a PPV of 0.67 (±0.05) and TPR of 0.51 (±0.05). The algorithm, trained on limited data and evaluated on clinically validated ground truth, has potential to assist OMF surgeons in detecting periapical lucencies on panoramic radiographs.

1 December 2022 in Radiology
Verified
Journal Article
Closed access
KBKeno Bressem
Keno Bressem
LALisa Adams
Lisa Adams
FPFabian Proft
Fabian Proft
KHKay Geert A. Hermann
Kay Geert A. Hermann
Torsten DiekhoffTorsten Diekhoff
Torsten Diekhoff
DPDenis Poddubnyy
Denis Poddubnyy
A deep learning tool was able to detect active inflammatory and structural changes indicative of axial spondyloarthritis at MRI of sacroiliac joints. Background MRI is frequently used for early diagnosis of axial spondyloarthritis (axSpA). However, evaluation is time-consuming and requires profound expertise because noninflammatory degenerative ...

14 September 2023 in Expert Systems with Applications
Verified
Journal Article
Closed access
KBKeno Bressem
Keno Bressem
JPJens-Michalis Papaioannou
Jens-Michalis Papaioannou
PGPaul Grundmann
Paul Grundmann
FBFlorian Borchert
Florian Borchert
LALisa Adams
Lisa Adams
ALAlexander Löser
Alexander Löser

13 January 2023 in Life
Verified
Journal Article
Open access
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JOJonas Oppenheimer
Jonas Oppenheimer
SLSophia Lüken
Sophia Lüken
BHBernd Hamm
Bernd Hamm
SNStefan Niehues
Stefan Niehues
Gleamer BoneView© is a commercially available AI algorithm for fracture detection in radiographs. We aim to test if the algorithm can assist in better sensitivity and specificity for fracture detection by residents with prospective integration into clinical workflow. Radiographs with inquiry for fracture initially reviewed by two residents were randomly assigned and included. A preliminary diagnosis of a possible fracture was made. Thereafter, the AI decision on presence and location of possible fractures was shown and changes to diagnosis could be made. Final diagnosis of fracture was made by a board-certified radiologist with over eight years of experience, or if available, cross-sectional imaging. Sensitivity and specificity of the human report, AI diagnosis, and assisted report were calculated in comparison to the final expert diagnosis. 1163 exams in 735 patients were included, with a total of 367 fractures (31.56%). Pure human sensitivity was 84.74%, and AI sensitivity was 86.92%. Thirty-five changes were made after showing AI results, 33 of which resulted in the correct diagnosis, resulting in 25 additionally found fractures. This resulted in a sensitivity of 91.28% for the assisted report. Specificity was 97.11, 84.67, and 97.36%, respectively. AI assistance showed an increase in sensitivity for both residents, without a loss of specificity.

8 April 2019 in Acta Radiologica Open
Verified
Journal Article
Open access
PDF file
SNStefan Niehues
Stefan Niehues
Timm DeneckeTimm Denecke
Timm Denecke
CBChristian Bassir
Christian Bassir
BHBernd Hamm
Bernd Hamm
MHMatthias Haas
Matthias Haas
Background: Intramural duodenal hematoma is a rare condition. Different imaging modalities are at hand for diagnosis. Purpose: To identify patients with intramural duodenal hematoma and report imaging findings and clinical courses. Material and Methods: Typical imaging patterns using ultrasound, computed tomography, and magnetic resonance imaging were carried out on 10 patients. Results: The mean patient age was 7.5 years. The average disease duration was 13 months. Clinical signs of improvement were observed within 16 days. Residues were still detectable at long-term follow-up. Conclusion: For patients with intramural duodenal wall hematoma, diagnosis should be considered early. Typical imaging findings should be known to ensure optimal treatment.