In this paper, we propose a new discrete-continuous codification of the Chu–Beasley genetic algorithm to address the optimal placement and sizing problem of the distribution static compensators (D-STATCOM) in electrical distribution grids. The discrete part of the codification determines the nodes where D-STATCOM will be installed. The continuous part of the codification regulates their sizes. The objective function considered in this study is the minimization of the annual operative costs regarding energy losses and installation investments in D-STATCOM. This objective function is subject to the classical power balance constraints and devices’ capabilities. The proposed discrete-continuous version of the genetic algorithm solves the mixed-integer non-linear programming model that the classical power balance generates. Numerical validations in the 33 test feeder with radial and meshed configurations show that the proposed approach effectively minimizes the annual operating costs of the grid. In addition, the GAMS software compares the results of the proposed optimization method, which allows demonstrating its efficiency and robustness.