Prof. John Inge Johnsen received his Ph.D. diploma at the University of Tromsö, Norway, in 1994. His thesis focused on the characterization of regulatory genetic elements in polyomaviruses and the effects these regulatory regions have on host–virus interaction. After finishing his Ph.D., he went on to pursue his main scientific interest: cancer biology, oncogenes, and tumor suppressor genes. In 1995, he joined the University of California, where he studied the effects of p53 and genes regulated by p53 on cancer development. After spending two years at the University of Tromsö as an assistant professor/lecturer, he joined Karolinska Institutet as a postdoctoral fellow, where he, together with Dr. Kogner, built up the childhood neural tumor research consortium. He became an associate professor at Karolinska Institutet in 2010. The main focus of his research group is to search for new treatment options that lead to better survival, fewer treatment-related complications, and better quality of life for children with medulloblastoma and neuroblastoma. This is achieved by applying different Omic techniques to characterize the molecular landscape of malignant and corresponding non-cancerous cells within the tumor microenvironment, using a translational approach to apply preclinical in vivo models to characterize the anti-tumorigenic effects of drugs and compounds targeting specific biological aberrations in cancer cells or populations of cells.