Krystyna Gromkowska-Kępka

Mrs. Krystyna Gromkowska-Kępka


Research Focus & Metrics

Academic Career Length

11Years (2016-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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2 March 2021 in Journal of Cosmetic Dermatology
Verified
Journal Article
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KGKrystyna Gromkowska-Kępka
Krystyna Gromkowska-Kępka
Anna Puścion-JakubikAnna Puścion-Jakubik
Anna Puścion-Jakubik
Renata Markiewicz-ŻukowskaRenata Markiewicz-Żukowska
Renata Markiewicz-Żukowska
Katarzyna SochaKatarzyna Socha
Katarzyna Socha
Background: Photoaging, ultra violet (UV) induced skin aging is a gradual process that depends on the time and intensity of solar radiation.Aim: The aim of this paper was to review of the literature focused on in vitro studies explaining the mechanisms of photoaging.Methods: Electronic databases, including PubMed and MEDLINE, were searched for in vitro studies on the importance of UV radiation in the skin photoaging process of peer‐reviewed scientific journals. Only articles available in English and full version publications were considered for this review.Results: Three main modes of UV radiation action on skin cells which lead to photoaging, there are changes in cell metabolism, induction of oxidative stress due to the change in enzyme activity.Conclusion: The information gathered in this publication will help to better understand the complex and multidirectional mechanism of skin photoaging, which will contribute to the development of research on potential cosmetic products that provide effective and safe sun protection or repair damage caused by UV radiation.

3 June 2021 in Healthcare
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Journal Article
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APAleksandra Podgórska
Aleksandra Podgórska
Anna Puścion-JakubikAnna Puścion-Jakubik
Anna Puścion-Jakubik
Renata Markiewicz-ŻukowskaRenata Markiewicz-Żukowska
Renata Markiewicz-Żukowska
KGKrystyna Gromkowska-Kępka
Krystyna Gromkowska-Kępka
Katarzyna SochaKatarzyna Socha
Katarzyna Socha
Acne vulgaris (AV) is a chronic disease that affects a significant percentage of the world’s population. Its development is influenced by both external and internal factors. The purpose of this review is to demonstrate the effect of basic nutrient intake on the exacerbation or alleviation of AV lesions. A retrospective review of publications in PubMed regarding diet therapy and the impact of individual nutrient intake on the skin condition of patients was conducted. Ingestion of products with a high glycaemic index may indirectly lead to sebum overproduction, which promotes infection with Cutibacterium acnes and causes inflammation. Consumption of certain dairy products may result in skin deterioration caused by the presence of hormones in these products, i.e., progesterone and testosterone precursors. The beneficial effect of fatty acids on the skin is manifested by the reduction in inflammation. Of significance in AV treatment are vitamins A, C, D, E and B, as well as mineral elements zinc and selenium. Proper nutrition may not only prevent or alleviate AV but also increase treatment efficacy.

25 September 2021 in Nutrients
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Anna Puścion-JakubikAnna Puścion-Jakubik
Anna Puścion-Jakubik
Joanna BieleckaJoanna Bielecka
Joanna Bielecka
MGMonika Grabia-Lis
Monika Grabia-Lis
AŻAnita Żmudzińska
Anita Żmudzińska
Renata Markiewicz-ŻukowskaRenata Markiewicz-Żukowska
Renata Markiewicz-Żukowska
Katarzyna SochaKatarzyna Socha
Katarzyna Socha
Food supplements (FS) are a concentrated source of vitamins, minerals, or other ingredients with nutritional or other physiological effects. Due to their easy availability, widespread advertising, and sometimes low price, increased consumption of this group of preparations has been observed. Therefore, the aim of the study was to assess the knowledge and intake of FS during the COVID-19 pandemic in Poland, with particular reference to FS containing zinc and vitamin D. It was noted that both of the above ingredients were used significantly more often by people with higher education (59.0%), with a medical background or related working in the medical field (54.5%), and/or exercising at home (60.1%). Preparations containing vitamin D were used by 22.8% of the respondents in the first wave, 37.6% in the second wave, and 32.9% in the third wave. To sum up, we showed the highest consumption of vitamin and mineral supplements, and preparations containing zinc and vitamin D were taken significantly more often by people with higher medical and related education. This indicates a high awareness of health aspects and the need for preventive measures in these groups.

20 December 2020 in Foods
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Journal Article
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Joanna BieleckaJoanna Bielecka
Joanna Bielecka
Renata Markiewicz-ŻukowskaRenata Markiewicz-Żukowska
Renata Markiewicz-Żukowska
PNPatryk Nowakowski
Patryk Nowakowski
MGMonika Grabia-Lis
Monika Grabia-Lis
Anna Puścion-JakubikAnna Puścion-Jakubik
Anna Puścion-Jakubik
Katarzyna SochaKatarzyna Socha
Katarzyna Socha
Background: Rice is one of the most commonly consumed grains. It could be a good source of nutrients in a diet, but its consumption could also contribute to exposure to toxic elements. All rice products available on the Polish market are imported, which may pose a particular concern as to the safety of their consumption. The aim of our study was to estimate the content of As, Cd, Pb, and Hg in rice products and to assess the health risk indicators related to exposure to toxic elements consumed with rice products among the adult population in Poland. Methods: A total of 99 samples from 12 groups of rice products (basmati, black, brown, parboiled, red, wild, white rice and expanded rice, rice flakes, flour, pasta, and waffles) available in the Polish market were obtained. The content of Hg was determined using the atomic absorption spectrometry method (AAS). To measure As, Cd, and Pb, inductively coupled plasma-mass spectrometry (ICP-MS) was used. The health risk was assessed by calculating several indicators. Results: The average As, Cd, Pb, and Hg contents in all studied products were 123.5 ± 77.1 μg/kg, 25.7 ± 26.5 μg/kg, 37.5 ± 29.3 μg/kg, and 2.8 ± 2.6 μg/kg, respectively. Exceedance of the limit established by the Polish National Food Safety Standard was observed in one sample as regards the As content and exceedance of the European Commission standard in two samples for Hg. The samples of foods imported from European markets (n = 27) had statistically higher As content (p < 0.05) than those imported from Asian countries (n = 53). The values of health risk indicators did not show an increased risk for the Polish adult population. However, the daily intake of 55 g of rice corresponds to the benchmark dose lower confidence limit (BMDL) for Pb. Conclusion: The studied rice products could be regarded as safe for consumption by the Polish population as far as the content of As, Cd, Pb, and Hg is concerned.

17 December 2020 in Foods
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Journal Article
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KMKonrad Mielcarek
Konrad Mielcarek
Anna Puścion-JakubikAnna Puścion-Jakubik
Anna Puścion-Jakubik
KGKrystyna Gromkowska-Kępka
Krystyna Gromkowska-Kępka
JSJolanta Soroczyńska
Jolanta Soroczyńska
Sylwia NaliwajkoSylwia Naliwajko
Sylwia Naliwajko
Katarzyna SochaKatarzyna Socha
Katarzyna Socha
The aim of the study was to assess protein, fat, salt, collagen, moisture content and energy value of freshwater fish purchased in Polish fish farms. Eight species of freshwater fish (raw, smoked, pickled) were assessed by near infrared spectroscopy (NIRS). The protein content varied between 15.9 and 21.7 g/100 g, 12.8 and 26.2 g/100 g, 11.5 and 21.9 g/100 g in raw, smoked and pickled fish, respectively. Fat content ranged from 0.89 to 22.3 g/100 g, 0.72 to 43.1 g/100 g, 0.01 to 29.7 g/100 g in raw, smoked and pickled fish, respectively. Salt content ranged from 0.73 to 1.48 g/100 g, 0.77 to 3.39 g/100 g, 1.47 to 2.29 g/100 g in raw, smoked and pickled fish, respectively. A serving (150 g) of each fish product provided 53.2–71.9% of the Reference Intake (RI) for protein, 2.21–60.3% of the RI for fat, 21.3–61.3% of the RI for salt and 6.27–24.4% kJ/6.29–24.5% kcal of the RI for energy. Smoked fish had a higher protein and also fat content than raw and pickled fish, while smoked and pickled fish had higher salt content than raw fish. Cluster analysis was performed, which allowed to distinguish, on the basis of protein, fat, salt, collagen and moisture content, mainly European eel.

31 August 2021 in Antioxidants
Verified
Journal Article
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KGKrystyna Gromkowska-Kępka
Krystyna Gromkowska-Kępka
Renata Markiewicz-ŻukowskaRenata Markiewicz-Żukowska
Renata Markiewicz-Żukowska
PNPatryk Nowakowski
Patryk Nowakowski
Sylwia NaliwajkoSylwia Naliwajko
Sylwia Naliwajko
JMJustyna Moskwa
Justyna Moskwa
Katarzyna SochaKatarzyna Socha
Katarzyna Socha
Young barley seems to be a promising material for use as nutricosmetic due to the presence of many biologically active compounds. The aim of this study was to evaluate the effect of Hordeum vulgare L. extracts on human skin fibroblasts exposed to ultraviolet radiation B (UVB) radiation. Analysis of the chemical composition showed a predominance of 9,12,15-octadecatrienoic acid. The quality assessment showed that young barley preparations have high total polyphenolic content (TPC) and favourable total antioxidant status (TAS). They also contain antioxidant elements such as zinc, copper, and selenium. Furthermore, the analyzed products were found to be safe in terms of toxic elements (lead, cadmium and mercury) and lack of cytotoxic effect of young barley extracts on cells. In vitro bioactivity assays showed that young barley extract increased the survival rate and accelerated the migration of fibroblasts in research models with UVB radiation. The application of both extracts caused an increase in DNA biosynthesis, and in the number of cells arrested in S phase. Moreover, an inhibitory effect of the tested extracts on the expression of matrix metalloproteinase 2 (MMP-2) and matrix metalloproteinase 9 (MMP-9) was observed. The results indicate that young barley extracts, due to protective as well as restorative effect, could potentially be used in the production of nutricosmetics and skin care products.