After completing masters in physical chemistry (from Tribhuvan University, Nepal), I joined The University of Akron, Ohio and received my 2nd Masters followed by PhD in bio-analytical chemistry under the supervision of Dr. Thomas C. Leeper in 2016. I initiated my Post-Doctoral education at UF in the NIH funded Southeastern Center for Integrated Metabolomics (SECIM) in 2016 under the supervision of Dr. Matthew E. Merritt for three years. As a SECIM post doc, I worked with samples ranging from body fluids to freeze clamped tissues from living systems. I also initiated metabolomics and fluxomic studies based on 1H, 2H, and 13C NMR in skeletal muscle as part of a NIH funded pilot project awarded to Elisabeth Barton (mechanics core PI). I worked with Dr. Walter and Barton as a Post-Doctoral Fellow (from July, 2018-July, 2019) to expand my knowledge of muscle and pathophysiology, particularly as related to the muscular dystrophies. From July, 2020 (in Dr. Terence Ryan's lab in UF), I am working on studies related to discovery of the mechanisms of muscle dysfunction in chronic kidney disease, impaired mitochondrial energetics as a driver of hemodialysis and the roles of PFKFB3 in peripheral artery disease.
Research Keywords & Expertise
Metabolomics
Multivariate Analysis
Nuclear Magnetic Reson...
Organic Synthesis
drug discovery and dev...
dynamic nuclear polari...
protein expression and...
cell culture and anima...
Fluxomics
Lipidomic profiling
High resolution magic ...
Fingerprints
43%
Metabolomics
37%
Nuclear Magnetic Resonance (NMR)
16%
High resolution magic angle spinning
6%
drug discovery and development
6%
dynamic nuclear polarization
Short Biography
After completing masters in physical chemistry (from Tribhuvan University, Nepal), I joined The University of Akron, Ohio and received my 2nd Masters followed by PhD in bio-analytical chemistry under the supervision of Dr. Thomas C. Leeper in 2016. I initiated my Post-Doctoral education at UF in the NIH funded Southeastern Center for Integrated Metabolomics (SECIM) in 2016 under the supervision of Dr. Matthew E. Merritt for three years. As a SECIM post doc, I worked with samples ranging from body fluids to freeze clamped tissues from living systems. I also initiated metabolomics and fluxomic studies based on 1H, 2H, and 13C NMR in skeletal muscle as part of a NIH funded pilot project awarded to Elisabeth Barton (mechanics core PI). I worked with Dr. Walter and Barton as a Post-Doctoral Fellow (from July, 2018-July, 2019) to expand my knowledge of muscle and pathophysiology, particularly as related to the muscular dystrophies. From July, 2020 (in Dr. Terence Ryan's lab in UF), I am working on studies related to discovery of the mechanisms of muscle dysfunction in chronic kidney disease, impaired mitochondrial energetics as a driver of hemodialysis and the roles of PFKFB3 in peripheral artery disease.