Flooding is a recurring event, and Bangladesh is particularly vulnerable to it. This study aimed to assess the Jamuna floodplain's community vulnerability. A concise overview of the literature had performed to identify and finalize the indicators of vulnerability. Expert judgments used to weight the selected indicators. Primary data were collected using a pretested questionnaire throughout the field, where 400 households have been interviewed. Using multi-stage sampling techniques, five Upazilas of Jamalpur district, including Dewanganj, Islampur, Madarganj, Melandaha, and Sharishabari, were purposively chosen following extensive flood damage reports. Percentage value was derived using SPSS for each variable collected from the field survey. The variable vulnerability index (VVI) was derived by dividing the weighting value by the field percentage value for each variable. Exposure, sensitivity, and adaptive capacity have been calculated using the variable vulnerability index values. Finally, using a widely recognized established index, the vulnerability was assessed for the study area. The calculated vulnerability scores for Dewanganj, Islampur, Madarganj, Melandaha and Sharishabari are 0.86, 0.84, 0.71, 0.70 and 0.65. According to the survey findings, all the study sites are found highly vulnerable to floods, especially Dewanganj and Islampur Upazilas, due to poor socio-economic conditions, low adaptive capacities, and high exposures. This study recommends resistant materials like brick and concrete in housing construction, sustainable flood-resistant dams and improving their adaptive capacities through socio-economic uplift.