Jun Kohyama

Dr. Jun Kohyama

Tokyo Bay Urayasu Ichikawa Medical Center, Urayasu, Japan 279-0001
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Research Focus & Metrics

Academic Career Length

41Years (1986-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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24 June 2021 in Children
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Journal Article
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JKJun Kohyama
Jun Kohyama
Sleep is one of the basic physiological processes for human survival. Both sleep quantity and sleep quality are fundamental components of sleep. This review looks at both sleep quantity and sleep quality, considering how to manage the complex but probably unavoidable physiological phenomenon of sleep. The need for sleep has marked variations between individuals, in addition to the effects of variable conditions. Studies on sleep quality started later than those on sleep quantity, beginning in 1989 when Ford and Kamerow revealed that insomnia increases the risk of psychiatric disorders. According to the nationwide research team on the quality of sleep (19FA0901), sleep quality is superior to sleep quantity as an index for assessing sleep, and that restfulness obtained through sleep is a useful index for assessing sleep quality. We should pay more attention to obtaining sleep of good quality (restfulness, no sleepiness, no need for more sleep, sufficient objective sleep depth, etc.), although there have not been enough studies on the associations between sleep quality and health or disorders in children and adolescents. Further studies using the deviation from an individual’s optimal sleep quantity may show us another aspect of the effects of sleep quantity on various life issues.

1 February 2003 in Archives of Disease in Childhood
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JKJun Kohyama
Jun Kohyama
JOJ S Ohinata
J S Ohinata
THT Hasegawa
T Hasegawa
Aims: To investigate blood pressure (BP) in children with sleep disordered breathing (SDB). Methods: BP was measured during single night polysomnography in 23 suspected SDB child patients with adenotonsillar hypertrophy, but without respiratory or heart failure, or coma. The age related changes of the observed BP were normalised to the BP index. The BP indices were examined in relation to SDB measures, such as the desaturation time (percentage of time with oxygen saturation (SaO2) <90% against the total sleep time), SaO2 nadir, apnoea-hypopnoea index (AHI), and arousal index, in addition to age and body mass index (BMI). Results: The systolic BP index during rapid eye movement sleep (REMS) tended to correlate with AHI, while the diastolic index during REM sleep showed a significant correlation with AHI. The BP indices during non-REMS and wakefulness showed no correlation with the parameters obtained. Patients with an AHI of 10 or more (n = 7, AHIhigh) had significantly higher systolic and diastolic BP indices during both wakefulness and REMS, compared with those with an AHI of less than 10 (n = 16, AHIlow). Two patients in AHIhigh showed no sleep related dip of diastolic BP, and three patients in AHIlow lacked the sleep related dip in systolic BP. By means of multiple regression analysis, age, BMI, and AHI were found to be significant predictor variables of the systolic BP index during REMS. Conclusions: BP in paediatric SDB patients is positively correlated with the degree of SDB.

1 January 2002 in Brain and Development
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Journal Article
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JKJun Kohyama
Jun Kohyama
FMFumie Matsukura
Fumie Matsukura
KKKaku Kimura
Kaku Kimura
NTNaoko Tachibana
Naoko Tachibana

3 April 2013 in BMC Research Notes
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JMJodi A Mindell
Jodi A Mindell
ABAlex Bartle
Alex Bartle
YAYoungmin Ahn
Youngmin Ahn
MRMahesh Babu Ramamurthy
Mahesh Babu Ramamurthy
HHHuynh Thi Duy Huong
Huynh Thi Duy Huong
DGDaniel Yt Goh
Daniel Yt Goh
The objective of this study was to assess the prevalence of education about sleep and sleep disorders in pediatric residency programs and to identify barriers to providing such education.

1 January 2011 in Journal of Physiological Anthropology
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JKJun Kohyama
Jun Kohyama
This article reviews evidence supporting the hypothesis that suicide rates in Japan could be reduced by elevating serotonin levels via increasing the average duration of sleep. Seven major relevant findings were apparent in the literature: 1) Sleep loss is associated with suicide, but the direction of causality is equivocal. 2) Decreased serotonergic activity may be involved in suicidal behavior. 3) Sleep debt may decrease serotonergic activity. 4) The suicide rate in Japan has remained at a heightened level for the past 12 years. 5) The average sleep duration in Japan has decreased over the past 40 years. 6) The average sleep duration in Japan is among the lowest in the world. 7) The average sleep duration in Japan plateaued in 1995 and has been relatively stable since. From the research reviewed, two major problematic issues were apparent: 1) Most people in Japan receive inadequate sleep. 2) Individuals whose sleep is inadequate are unlikely to be sufficiently physically active to stimulate serotonergic systems to a desirable level. I propose that public health initiatives encouraging a longer duration of sleep may provide a relatively simple way of addressing the disturbing current trend in Japan. The combination of actigraph and brain serotonin level measurement could allow large population-based cohort studies to be designed, to elucidate the causal links between sleep duration, serotonin levels, and suicide rates.

1 April 2002 in Journal of Developmental & Behavioral Pediatrics
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JKJun Kohyama
Jun Kohyama
TSToshihide Shiiki
Toshihide Shiiki
JOJunko Ohinata-Sugimoto
Junko Ohinata-Sugimoto
THTakeshi Hasegawa
Takeshi Hasegawa
To examine the sleep habits of 3-year-old children, we questioned guardians during a routine health examination for 3-year-old children at a public health center. According to the 1105 questionnaires analyzed, the proportion of children who fell asleep at 10 p.m. or later was 49.6%. The nocturnal sleep onset time was significantly correlated with the wake-up time in the morning and was significantly negatively correlated with the nocturnal sleep duration. The average daily total sleep duration (nocturnal sleep duration + nap duration) of regular nap-takers showed a significant negative correlation with the nocturnal sleep onset time. The average values for height, weight, and body mass index (BMI) were not correlated with the nocturnal sleep onset time. Children who went to sleep later got less sleep than those who went to sleep earlier. Because sleep debt has a harmful impact on older children and adults, late sleep onset may have adverse health consequences in young children.