Suchitra Krishnan-Sarin

Prof. Suchitra Krishnan-Sarin


Research Focus & Metrics

Academic Career Length

32Years (1995-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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6 December 2014 in Nicotine & Tobacco Research
Verified
Journal Article
Closed access
PDF file
GKGrace Kong
Grace Kong
MMMeghan E. Morean
Meghan E. Morean
DCDana A. Cavallo
Dana A. Cavallo
DCDeepa R. Camenga
Deepa R. Camenga
SKSuchitra Krishnan-Sarin
Suchitra Krishnan-Sarin
Understanding why young people try and stop electronic cigarette (e-cigarette) use is critical to inform e-cigarette regulatory efforts. We conducted 18 focus groups (N = 127) in 1 middle school (MS), 2 high schools (HSs), and 2 colleges in Connecticut to assess themes related to e-cigarette experimentation and discontinuation. We then conducted surveys to evaluate these identified themes in 2 MSs, 4 HSs, and 1 college (N = 1,175) to explore whether reasons for e-cigarette experimentation and/or discontinuation differed by school level or cigarette smoking status. From the focus groups, we identified experimentation themes (i.e., curiosity, flavors, family/peer influence, easy access, and perceptions of e-cigarettes as “cool” and as a healthier/better alternative to cigarettes) and discontinuation themes (i.e., health concerns, loss of interest, high cost, bad taste, and view of e-cigarettes as less satisfying than cigarettes). The survey data showed that the top reasons for experimentation were curiosity (54.4%), appealing flavors (43.8%), and peer influences (31.6%), and the top reasons for discontinuation were responses related to losing interest (23.6%), perceiving e-cigarettes as “uncool” (16.3%), and health concerns (12.1%). Cigarette smokers tried e-cigarettes because of the perceptions that they can be used anywhere and to quit smoking and discontinued because they were not as satisfying as cigarettes. School level differences were detected. E-cigarette prevention efforts toward youth should include limiting e-cigarette flavors, communicating messages emphasizing the health risks of use, and changing social norms surrounding the use of e-cigarettes. The results should be interpreted in light of the limitations of this study.

1 November 2007 in Nicotine & Tobacco Research
Verified
Journal Article
Closed access
PDF file
TCTransdisciplinary Tobacco Use Resea Center
Transdisciplinary Tobacco Use Resea Center
TWTobacco Dependence Phenotype Workgroup
Tobacco Dependence Phenotype Workgroup
TBTimothy B. Baker
Timothy B. Baker
MPMegan E. Piper
Megan E. Piper
DMDanielle E. McCarthy
Danielle E. McCarthy
BTBenjamin A. Toll
Benjamin A. Toll
An inability to maintain abstinence is a key indicator of tobacco dependence. Unfortunately, little evidence exists regarding the ability of the major tobacco dependence measures to predict smoking cessation outcome. This paper used data from four placebo-controlled smoking cessation trials and one international epidemiological study to determine relations between cessation success and the Fagerström Test for Nicotine Dependence (FTND), the Heaviness of Smoking Index, the Nicotine Dependence Syndrome Scale, and the Wisconsin Inventory of Smoking Dependence Motives. Results showed that much of the predictive validity of the FTND could be attributed to its first item, time to first cigarette in the morning, and this item had greater validity than any other single measure. Thus the time-to-first-cigarette item appears to tap a pattern of heavy, uninterrupted, and automatic smoking and may be a good single-item measure of nicotine dependence.

1 February 2002 in Psychopharmacology
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Journal Article
Closed access
PDF file
SOStephanie S. O'Malley
Stephanie S. O'Malley
SKSuchitra Krishnan-Sarin
Suchitra Krishnan-Sarin
CFConor Farren
Conor Farren
RSRajita Sinha
Rajita Sinha
MKMary Kreek
Mary Kreek

1 April 2007 in Drug and Alcohol Dependence
Verified
Journal Article
Closed access
SKSuchitra Krishnan-Sarin
Suchitra Krishnan-Sarin
BRBrady Reynolds
Brady Reynolds
ADAmy M. Duhig
Amy M. Duhig
ASAnne Smith
Anne Smith
TLThomas Liss
Thomas Liss
MPMarc N. Potenza
Marc N. Potenza

1 December 2010 in Pediatrics
Verified
Journal Article
Open access
PDF file
RDRani A. Desai
Rani A. Desai
SKSuchitra Krishnan-Sarin
Suchitra Krishnan-Sarin
DCDana Cavallo
Dana Cavallo
MPMarc N. Potenza
Marc N. Potenza
OBJECTIVE: Video game playing may negatively impact youth. However, the existing literature on gaming is inconsistent and often has focused on aggression rather than the health correlates of gaming and the prevalence and correlates of problematic gaming. METHODS: We anonymously surveyed 4028 adolescents about gaming and reported problems with gaming and other health behaviors. A total of 51.2% of the sample reported gaming (76.3% of boys and 29.2% of girls). RESULTS: There were no negative health correlates of gaming in boys and lower odds of smoking regularly; however, girls who reported gaming were less likely to report depression and more likely to report getting into serious fights and carrying a weapon to school. Among gamers, 4.9% reported problematic gaming, defined as reporting trying to cut back, experiencing an irresistible urge to play, and experiencing a growing tension that could only be relieved by playing. Boys were more likely to report these problems (5.8%) than girls (3.0%). Correlates of problematic gaming included regular cigarette smoking, drug use, depression, and serious fights. Results suggest that gaming is largely normative in boys and not associated with many health factors. In girls, however, gaming seems to be associated with more externalizing behaviors and fewer internalizing symptoms. CONCLUSIONS: The prevalence of problematic gaming is low but not insignificant, and problematic gaming may be contained within a larger spectrum of externalizing behaviors. More research is needed to define safe levels of gaming, refine the definition of problematic gaming, and evaluate effective prevention and intervention strategies.

1 June 2005 in Archives of General Psychiatry
Verified
Journal Article
Closed access
KSKristi A. Sacco
Kristi A. Sacco
ATAngelo Termine
Angelo Termine
ASAisha Seyal
Aisha Seyal
MDMelissa M. Dudas
Melissa M. Dudas
JVJennifer C. Vessicchio
Jennifer C. Vessicchio
TGTony P. George
Tony P. George
Cigarette smoking rates in schizophrenia are higher than in the general population. To determine whether cigarette smoking modifies cognitive deficits in schizophrenia and to establish the role of nicotinic acetylcholine receptors (nAChRs) in mediating cigarette smoking-related cognitive enhancement. Neuropsychological assessments were performed at smoking baseline, after overnight abstinence, and after smoking reinstatement across 3 separate test weeks during which subjects were pretreated in a counterbalanced manner with the nonselective nAChR antagonist mecamylamine hydrochloride (0, 5, or 10 mg/d). Twenty-five smokers with schizophrenia and 25 control smokers. Outpatient mental health center. Visuospatial working memory (VSWM) and Continuous Performance Test (CPT) scores. In smokers with schizophrenia and control smokers, overnight abstinence led to undetectable plasma nicotine levels and an increase in tobacco craving. While abstinence reduced CPT hit rate in both groups, VSWM was only impaired in smokers with schizophrenia. Smoking reinstatement reversed abstinence-induced cognitive impairment. Enhancement of VSWM and CPT performance by smoking reinstatement in smokers with schizophrenia, but not the subjective effects of smoking, was blocked by mecamylamine treatment. Cigarette smoking may selectively enhance VSWM and attentional deficits in smokers with schizophrenia, which may depend on nAChR stimulation. These findings may have implications for understanding the high rates of smoking in schizophrenia and for developing pharmacotherapies for cognitive deficits and nicotine dependence in schizophrenia.