This study aimed to fabricate the potential therapeutic scaffold to efficiently and safely fastening skin wound healing. A biocompatible grafting polymer-based thermal sensitive hybrid hydrogel (Chitosan-P123, CP) containing gelatin and curcumin was designed to be suitable stiffness for tissue regeneration. A detailed in the rheological study found that the encapsulated agents induced the change in the stiffness of the hydrogel from the hard to the soft. Especial, the thermally induced phase transition of CP hydrogel was governed by the participant of gelatin rather than curcumin. For example, at 25 wt% gelatin, CP hydrogel exhibited a unique gel-sol-gel transition following the function of temperature. Moreover, in vitro investigation revealed that the hybrid hydrogel provides the capacity of especially induced curcumin release with a sustainable rate as well as the excellent biocompatibility scaffold. Altogether with in vivo study, the hybrid hydrogel highlighted the advance of the dual synergistic of curcumin and gelatin in development of smart scaffold system, which promoted the efficacy in the regeneration of the structure and the barrier's function of damaged skin such as wound or skin cancer.

Lanthanum (La)-doped zinc oxide nanoparticles were synthesized with different La concentrations by employing a gel combustion method using poly(vinyl alcohol) (PVA). The as-synthesized photocatalysts were characterized using various techniques, including X-ray diffraction (XRD), transmission electron microscopy (TEM), energy dispersive X-ray analysis (EDX), photoluminescence (PL) spectroscopy, and UV–visible absorption spectroscopy. The average size of ZnO nanoparticles decreased from 34.3 to 10.3 nm with increasing concentrations of La, and the band gap, as evaluated by linear fitting, decreased from 3.10 to 2.78 eV. Additionally, it was found that the photocatalytic activity of doped samples, as investigated by using methyl orange dye under visible lights, improved in response to the increase in La concentration. The decomposition of methyl orange reached 85.86% after 150 min in visible light using La0.1Zn0.9O as the photocatalyst.

In the present article, the optimization of removal of Cu²⁺, Ni²⁺, and Pb²⁺ using sugarcane-based activated carbon was studied. The activated carbon synthesized from low-cost sugarcane bagasse via ZnCl₂ activation process was found to possess surprisingly high surface area (>1500 m²/g). In adsorption study, the individual and interactive effects of three critical parameters including initial concentration, pH of solution, and activated carbon dosage on removal efficiency of Cu²⁺, Ni²⁺, and Pb²⁺ were assessed by applying the response surface methodology combined with central composite design. The established second-order polynomial regression models provided an excellent interpretation of experimental data with acceptable coefficients of determination ( R²) and analysis of variance demonstrated statistical significance of the model terms. In the examined region, the predicted maximum removal efficiency and adsorption capacity were found in the order: Ni²⁺ (66.4%, 2.99 mg/g) < Cu²⁺ (90%, 13.24 mg/g) < Pb²⁺ (99.9%, 19.3 mg/g), which were also confirmed in the verification experiments.