Aim: The current paper aims to review mandibular flexure and its clinical implications in the field of oral rehabilitation. Mandibular flexure is a deformity of the mandible, which occurs during jaw movements. Methods and Materials: An electronic database search was conducted using the PRISM model, with a total of 49 articles included. Results: Mandibular flexure affects various stages of oral rehabilitation treatments. Effects of mandibular flexure are more significant in periodontal patients, and in implant-supported restorations, compared to natural teeth, due to differences in the force absorption by the periodontal ligament. Various adjustments must be made to the prosthodontic framework to enable long-term survival of the restorative treatments. Conclusions: Dental practitioners should pay attention to the following: (1) digital impressions are preferred over conventional; (2) mouth opening should be kept to a minimum (as possible, up to 10–20 mm) while also avoiding any anterior movements of the mandible (protrusion); (3) the number of abutment teeth should be kept to a minimum; (4) structures in the lower jaw should be splitted; (5) non-rigid connectors should be used to reduce the effort exerted; (6) in periodontal patients, the preference is for short-span restorations and non-rigid connectors; (7) in implant-supported restorations, it is preferable to divide the framework into two or three segments, utilizing rigid materials with a low elastic modulus. There is no agreement in the literature about the preferred location of the implants in the jaw.

Aim: The current study aims to assess levels of knowledge among Israeli dentists about rare diseases with orofacial manifestations, and whether occupational, regional and social factors influence those levels. Materials and Methods: A total of 309 Israeli dentists participated in an online survey that provided basic demographic information pertaining to their knowledge about rare diseases, their clinical experience with rare diseases, what further information they considered necessary, and which sources of information they most frequently utilize. Results: Young age, country of dental education, practicing in both public and private settings, as well as the number of hours allocated to dental studies and the opportunity to acquire information on rare diseases with orofacial manifestations, all seem to affect the level of knowledge. Conclusions: Developments in the field of rare disease are constantly ongoing, and improvements in post-graduate dental studies about them should keep pace. The results of the current study reveal the areas upon which such curricula should focus with respect to dental practitioners.

Composite resin restorations in primary teeth frequently fail due to secondary caries, which result from bacterial colonization and acid production at the tooth-restoration interface. This study aimed to evaluate whether composite resins containing quaternary ammonium silica (QASi), known for their antibacterial properties, can reduce bacterial acidification and lower the risk of secondary caries in high-caries-risk children compared to conventional restoratives. Saliva samples (10 µL saliva, ∼10⁶ bacteria) from 34 high-caries-risk children were applied ex vivo directly to three restorative materials: (i) Infinix with 1.5% QASi (Nobio), (ii) Filtek Supreme (3 M), and (iii) amalgam (Silmet). Samples were incubated with growth media supplemented with 2.5% dextrose at 37 °C for 24 hours. Bacterial growth and pH decrease were measured, by turbidity and colour change, every 20 minutes. Controls included saliva alone and a blank polystyrene surface. Repeated-measures ANOVA showed Infinix had the slowest pH decline, followed by amalgam, while Filtek Supreme's pH drop matched the control (p<0.001). Infinix also exhibited the lowest bacterial growth rate (p<0.001). Saliva bacteria from high-caries-risk children exhibit significantly slower pH decrease on Infinix composite resins compared to conventional restoratives. Composite resins with quaternary ammonium silica (QASi) fillers effectively inhibit bacterial growth and acid production, helping to prevent secondary caries and enamel demineralization. These bioactive materials offer a promising solution for improving the longevity of restorations, especially in high-caries-risk pediatric patients.