Dengue, Zika and Chikungunya are RNA Arboviruses present in some areas of Mexico, mainly in the endemic state of Chiapas that is characterized by presence of the vector that transmit them and an ecology that favors high transmission. According to the national epidemiological surveillance system, Dengue has intensified since 2018 and outbreaks continue in various states while for Zika and Chikungunya a decrease in cases has been reported in recent years. The main objective of this study was to determine the incidence of Dengue, Zika and Chikungunya infections during pregnancy in the state of Chiapas. The presence of previous and current infections and coinfections diagnosed by molecular (RT-PCR) and immunological (ELISA for IgG determination) techniques indicates a wide circulation of viruses in asymptomatic people, specifically in pregnant women showing that silent infections in dry season contributes to the preservation of viruses. From 136 studied samples, 27.7% tested positive for DENV, 8% for ZIKV and 24.1% for CHIKV by RTPCR and the values of IgG in sera show that 83.9% were positive for IgG antibodies against DENV, 65% against ZIKV and 59.1% against CHIKV. Results demonstrated presence of ZIKV and CHIKV, not detected by the epidemiological surveillance system, so the importance of establishing proactive epidemiological systems more strict, especially because these infections in pregnant women can cause severe health problems for newborn children. A study was conducted in a group of pregnant women from a region of southern Mexico where Dengue, Zika and Chikungunya are endemic to determine the presence of three viral infections, clinical manifestations and congenital damage in newborns. Epidemiological surveillance of diseases is mainly based on the incidence of these diseases; however, asymptomatic carriers also play an important role in disease transmission and are generally not included in the systems. In the case of the three arbovirosis studied, asymptomatic infections can occur until 60–70% of cases and play an important role in the disease transmission and level of protection of population. The three arboviruses, transmitted by the bite of the Aedes aegypti mosquito, in the same endemic scenario have the possibility of producing a high rate of asymptomatic infections and coinfections, which may go unnoticed. The study provides valuable information to improve knowledge of transmission in a period of low transmission (dry season) and also to understand that silent transmission has medical importance, especially in pregnancy, due the congenital damage that can cause to newborn. Therefore, it is important to design strategies to incorporate information into the national and international epidemiological surveillance system.