Lina Sabatino

Prof. Lina Sabatino

Department of Sciences and Technologies, University of Sannio, Via Francesco de Sanctis, 82100 Benevento, Italy
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Biography

Associate Professor of Molecular Biology at the Department of Science and Technology, University of Sannio. Ph.D. in "Earth and Life Sciences" at the University of Sannio. Postgraduate specialization diploma in "Clinical Biochemistry", University of Naples "Federico II'' with 70/70 cum laude. Degree in biological sciences, University of Naples "Federico II". My scientific interests are the following: - Identification and functional analysis of microRNAs involved in the pathogenesis of colorectal and breast cancer; - Analysis of the cellular response to stress and characterization of the molecular determinants of immunogenic cell death and immunogenic surrender; - Effects on cellular and mitochondrial metabolism produced by exogenous stimuli and modifications by endogenous microRNAs; - Identification of natural and synthetic compounds and molecular characterization of their effects in in vitro cellular systems and in vivo animal models; - Epigenetic modifications and their role in the epithelial–mesenchymal transition that occurs in the tumor process; - Analysis of the genes that regulate the circadian rhythm and their relationship with cellular metabolism and transformation; Study of peroxisome proliferator-activated nuclear receptors (PPARs) under conditions of differentiation, inflammation and neoplastic transformation.

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