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Dr. Bin Li
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Academic Career Length
25Years (2002-Present)
(Calculated once Scilit publication data is synced: current year − year of first publication + 1)
Representative Publications
View All Publications1 July 2016 in Ultrasonics Sonochemistry
Journal Article
WXWenfei Xiong
Wenfei XiongYWYuntao Wang
Yuntao Wang
CZChunlan Zhang
Chunlan Zhang
JWJiawei Wan
Jiawei Wan
BSBakht Ramin Shah
Bakht Ramin ShahBLBin Li
Bin Li +3
Influence of high intensity ultrasound (HIUS) on the structure and properties of ovalbumin (OVA) were investigated. It was found that the subunits and secondary structure of OVA did not change significantly with HIUS treatment from the electrophoretic patterns and circular dichroism (CD) spectrum. The amount of free sulfhydryl groups increased and intrinsic fluorescence spectra analysis indicated changes in the tertiary structure and partial unfold of OVA after sonication increased. Compared with the untreated OVA, HIUS treatment increased the emulsifying activity and foaming ability, and decreased interface tension (oil-water and air-water interface), which due to the increased surface hydrophobicity and decreased the surface net charge in OVA, while the emulsifying and foaming stability had no remarkable differences. The increased particle size may be attributed to formation of protein aggregates. Moreover, the gelation temperatures of HIUS-treated samples were higher than the untreated OVA according to the temperature sweep model rheology, and this effect was consistent with the increased in surface hydrophobicity for ultrasound treated OVA. These changes in functional properties of OVA would promote its application in food industry.
Journal Article
Severe bone damage from diseases, including extensive trauma, fractures, and bone tumors, cannot self-heal, while traditional surgical treatment may bring side effects such as infection, inflammation, and pain. As a new biomaterial with controllable mechanical properties and biocompatibility, hydrogel is widely used in bone tissue engineering (BTE) as a scaffold for growth factor transport and cell adhesion. In order to make hydrogel more suitable for the local treatment of bone diseases, hydrogel preparation methods should be combined with synthetic materials with excellent properties and advanced technologies in different fields to better control drug release in time and orientation. It is necessary to establish a complete method to evaluate the hydrogel’s properties and biocompatibility with the human body. Moreover, establishment of standard animal models of bone defects helps in studying the therapeutic effect of hydrogels on bone repair, as well as to evaluate the safety and suitability of hydrogels. Thus, this review aims to systematically summarize current studies of hydrogels in BTE, including the mechanisms for promoting bone synthesis, design, and preparation; characterization and evaluation methods; as well as to explore future applications of hydrogels in BTE.
1 June 2018 in Food Chemistry
Journal Article
WXWenfei Xiong
Wenfei XiongCRCong Ren
Cong Ren
MTMo Tian
Mo Tian
XYXuejun Yang
Xuejun Yang
JLJing Li
Jing Li
BLBin Li
Bin Li9 January 2015 in RSC Advances
Journal Article
HLHongshan Liang
Hongshan Liang
BZBin Zhou
Bin Zhou
LHLei He
Lei He
YAYaping An
Yaping An
LLLiufeng Lin
Liufeng Lin
BLBin Li
Bin Li +3
In this article, we report the successful assembly of nanoparticles (NPs) from a water-soluble chitosan (CS) derivative (N-(2-hydroxyl)propyl-3-trimethyl ammonium chitosan chloride, HTCC) and zein via a low-energy phase separation method. The fabricated NPs were investigated for the first time to encapsulate and protect curcumin (Cur). The particle size and zeta potential of the zein–HTCC NPs varied from 66 to 170 nm and +36.3 to +62.5 mV, respectively. The encapsulation efficiency (EE) was greatly improved to 94.9% after HTCC coating, compared with 85.2% that using zein as a single encapsulant. The microstructure of the NPs was revealed by transmission electron microscopy (TEM). The physicochemical and structural analysis showed that the electrostatic interactions and hydrogen bonds were the major forces responsible for the formation of NPs. The encapsulation forms were evaluated for their efficiency in overcoming Cur's heat and UV sensitivity, which improve the stability about 2.7 fold, 3.5 fold and 2.5 fold when disposed with 60 °C treatment for 30 min, 80 °C treatment for 1 min and ultraviolet radiation for 2 h, respectively at zein–HTCC1 = 1 : 1. The results of the stability and DPPH assays indicated that the bioactivity was being protected upon encapsulation. Zein–HTCC NPs are believed to be promising delivery systems for the supplementation or treatment of hydrophobic nutrients or drugs.
1 October 2018 in Food Research International
Journal Article
CRCong Ren
Cong Ren
WXWenfei Xiong
Wenfei XiongDPDengfeng Peng
Dengfeng Peng
YHYun He
Yun He
PZPeiyuan Zhou
Peiyuan Zhou
BLBin Li
Bin Li +1
1 November 2016 in Food Research International
Journal Article
About Me
Prof. Bin Li is the Executive Vice President of the
Graduate School of Huazhong Agricultural University. He has been engaged in
research and teaching in the field of colloidal physical properties and
nutrition for a long time, mainly in the fields of food carbohydrates, food
colloidal nutrition, food component assembly behavior and mechanism, nutrient
homeostasis and delivery. He has presided over more than 30 projects
including the National Key Research and Development Plan, National Support Plan,
National Natural Science Foundation project, National “863” project, National “863”
key project sub-project, Hubei Province Technology Innovation Special project,
Hubei Province Key Natural Science Fund, Hubei Agriculture public welfare
project, Three Gorges Immigration Science and Technology Project, the
Ministry of Education doctoral fund, and more than 10 horizontal topics. He
has applied for 24 patents, 19 of which have been authorized and 17 of which have
been successfully transformed, and more than 100 SCI papers have been published
with him as the first or corresponding author. He hosted and participated in winning the
second prize of National Scientific Progress, the first prize of Hubei Science
and Technology Progress, and the second prize of Hubei Natural Science. He is
the winner of the Hubei Province Outstanding Youth Fund and the winner of the Huo
Yingdong Foundation Young Teachers Award.