In this paper, we discuss a possible combination of Earthquake Early Warning (EEW) and Neo-deterministic Seismic Hazard Assessment (NDSHA), and propose a new warning model, EEW2.0. The aim is to provide a differentiated warning alert to various end-users based on the results of seismic hazard assessment evaluation. The implementation of such a system contains three basic steps: (a) classification of “potential to cause hazard” in terms of magnitude; (b) determination of the source areas and building a hazard database in terms of Modified Mercalli Intensity (MMI) maps, considering all possible earthquake scenarios in the source area, for the whole protected area; (3) equipping unique decision framework for specific end-users. When a damaging earthquake (M ≥ 5.0) is detected, EEW2.0 quickly matches the prepared MMI map by estimated magnitude and epicenter, then directly extracts the MMI value and issues an early warning to the public. With the great attention and resources put into the reduction in seismic and its secondary risk in the 21st century, the proposed EEW2.0 will likely play an active role in protecting lives and reducing economic losses.