Zdenek Zadak

Prof. Dr. Zdenek Zadak

University Hospital Hradec Králové, Department of Research and Development, Head of Department, Sokolská Str. 581, 500 05 Hradec Králové, Czech Republic
orcid

Research Focus & Metrics

Academic Career Length

45Years (1982-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 February 2000 in Journal of Chromatography B: Biomedical Sciences and Applications
Verified
Journal Article
Closed access
RHRadomír Hyspler
Radomír Hyspler
ŠCŠárka Crhová
Šárka Crhová
JGJiřı́ Gasparič
Jiřı́ Gasparič
ZZZdenek Zadak
Zdenek Zadak
MČMarie Čı́žKová
Marie Čı́žKová
VBVěra Balasová
Věra Balasová

1 January 2009 in Physiological Research
Verified
Journal Article
Closed access
ZZZdenek Zadak
Zdenek Zadak
RHR Hyšpler
R Hyšpler
ATA Tichá
A Tichá
MHM Hronek
M Hronek
PFP Fikrová
P Fikrová
RŠR Štětina
R Štětina
Various reactive oxygen species (ROS) may be produced from normal biochemical, essential metabolic processes or from external sources as exposure to a variety of agents presented in the environment. Lipids, proteins, carbohydrates and DNA are all capable of reacting with ROS and can be implicated in etiology of various human disorders (rheumatoid arthritis, reperfusion injury, atherosclerosis, lung diseases etc.). In the organism damage by ROS is counteracted with natural antioxidants (glutathione peroxidases, superoxide dismutases, catalase, glutathione, ubiquinol, uric acid, and essential minerals) and nutritional antioxidants from diet (i.e. vitamins E, C, carotenoids). Possible mechanisms of nutritional depletion and side effects of high intake are in the article described.

1 April 2002 in Journal of Chromatography B
Verified
Journal Article
Closed access
RHRadomír Hyspler
Radomír Hyspler
ATAlena Ticha
Alena Ticha
MIMonika Indrová
Monika Indrová
ZZZdenek Zadak
Zdenek Zadak
LHLidmila Hyšplerová
Lidmila Hyšplerová
JCJaroslav Churáček
Jaroslav Churáček

1 July 2017 in Advances in Nutrition
Verified
Journal Article
Closed access
PDF file
APAnna Patkova
Anna Patkova
VJVera Joskova
Vera Joskova
EHEduard Havel
Eduard Havel
MKMiroslav Kovarik
Miroslav Kovarik
MKMonika Kucharova
Monika Kucharova
MHMiloslav Hronek
Miloslav Hronek
The guidelines for nutritional support in critically ill adult patients differ in various aspects. The optimal amount of energy and nutritional substr

1 December 2008 in Biomedical Papers
Verified
Journal Article
Open access
PDF file
PVPavel Vyroubal
Pavel Vyroubal
CCCarlo Chiarla
Carlo Chiarla
IGIvo Giovannini
Ivo Giovannini
RHRadek Hyspler
Radek Hyspler
ATAlena Ticha
Alena Ticha
ZZZdenek Zadak
Zdenek Zadak
BACKGROUND: Cholesterol is an essential component of cell membranes, precursor of steroids, biliary acids and other components of serious importance in live organism. Cholesterol synthesis is a complicated and energy-demanding process. Real da...

1 June 2010 in Journal of Critical Care
Verified
Journal Article
Closed access
CCCarlo Chiarla
Carlo Chiarla
IGIvo Giovannini
Ivo Giovannini
FGFELICE GIULIANTE
FELICE GIULIANTE
ZZZdenek Zadak
Zdenek Zadak
MVMaria Vellone
Maria Vellone
GNGennaro Nuzzo
Gennaro Nuzzo