Cardiac arrest (CA) is a fatal acute event. The development of new CA early warning system based on time series of vital signs from electronic health records (EHR) has great potential to reduce CA damage. In this process, recursive architecture-based deep learning, as a powerful tool for time series data processing, enables automatically extract features from various monitoring clinical parameters and to further improve the performance for acute critical illness prediction. However, the unexplainable nature and excessive time caused by black box structure with poor parallelism are the limitations of its development, especially in the CA clinical application with strict requirement of emergency treatment and low hidden dangers. In this study, we present an explainable and efficient deep early warning system for CA prediction, which features are captured by an efficient temporal convolutional network (TCN) on EHR clinical parameters sequence and explained by deep Taylor decomposition (DTD) theoretical framework. To demonstrate the feasibility of our method and further evaluate its performance, prediction and explanation experiments were performed. Experimental results show that our method achieves superior CA prediction accuracy compared with standard national early warning score (NEWS), in terms of overall AUROC (0.850 Vs. 0.476) and F1-Score (0.750 Vs. 0.450). Furthermore, our method improves the interpretability and efficiency of deep learning-based CA early warning system. It provides the relevance of prediction results for each clinical parameter and about 1.7 times speed enhancement for system calculation compared with the long short-term memory network.

The data generated by the structured electronic medical records is helpful for mining and extracting medical data, and it is an effective way to make effective use of valuable data resources. However, the hospitals have accumulated a large number of unstructured data in electronic medical records, which cannot be effectively searched, resulting in serious waste of resources. In this paper, we study the problem of extracting attribute values from the unstructured text in electronic medical records. By observing intestinal cancer diagnostic texts, our attributes have two categories - discriminative attributes and extractive attributes, which use the text classification and the sequence labeling to tackle attribute values extraction problems. For discriminative attributes, we firstly divide the text into sentences/segments as instances. Secondly, we fine-tune the pre-trained word embedding to capture domain-specific semantics/knowledge. Thirdly, we also use an attention mechanism to select the most important instance for different attribute extractors. Finally, multi-tasking learning is used to share useful information to get better experimental results. For extractive attributes, we propose a novel model to get attribute values, including the BiLSTM layer, the CNN layer and the CRF layer. In particular, we use BiLSTM and CNN to learn text features and CRF as the last layer of the model. Experiments have shown that our method is superior to several competitive baseline methods.

Background: The application of big data resources and the development of medical collaborative networks (MCNs) boost each other. However, MCNs are often assumed to be exogenous. How big data resources affect the emergence, development, and evolution of endogenous MCNs has not been well explained. Objective: This study aimed to explore and understand the influence of the mechanism of a wide range of shared and private big data resources on the transaction efficiency of medical services to reveal the impact of big data resources on the emergence and development of endogenous MCNs. Methods: This study was conducted by administering a survey questionnaire to information technology staff and medical staff from 132 medical institutions in China. Data from information technology staff and medical staff were integrated. Structural equation modeling was used to test the direct impact of big data resources on transaction efficiency of medical services. For those big data resources that had no direct impact, we analyzed their indirect impact. Results: Sharing of diagnosis and treatment data (β=.222; P=.03) and sharing of medical research data (β=.289; P=.04) at the network level (as big data itself) positively directly affected the transaction efficiency of medical services. Network protection of the external link systems (β=.271; P=.008) at the level of medical institutions (as big data technology) positively directly affected the transaction efficiency of medical services. Encryption security of web-based data (as big data technology) at the level of medical institutions, medical service capacity available for external use, real-time data of diagnosis and treatment services (as big data itself) at the level of medical institutions, and policies and regulations at the network level indirectly affected the transaction efficiency through network protection of the external link systems at the level of medical institutions. Conclusions: This study found that big data technology, big data itself, and policy at the network and organizational levels interact with, and influence, each other to form the transaction efficiency of medical services. On the basis of the theory of neoclassical economics, the study highlighted the implications of big data resources for the emergence and development of endogenous MCNs.

BACKGROUND The application of big data resources and the development of medical collaborative networks (MCNs) boost each other. However, MCNs are often assumed to be exogenous. How big data resources affect the emergence, development, and evolution of endogenous MCNs has not been well explained. OBJECTIVE This study aimed to explore and understand the influence of the mechanism of a wide range of shared and private big data resources on the transaction efficiency of medical services to reveal the impact of big data resources on the emergence and development of endogenous MCNs. METHODS This study was conducted by administering a survey questionnaire to information technology staff and medical staff from 132 medical institutions in China. Data from information technology staff and medical staff were integrated. Structural equation modeling was used to test the direct impact of big data resources on transaction efficiency of medical services. For those big data resources that had no direct impact, we analyzed their indirect impact. RESULTS Sharing of diagnosis and treatment data (β=.222; P=.03) and sharing of medical research data (β=.289; P=.04) at the network level (as big data itself) positively directly affected the transaction efficiency of medical services. Network protection of the external link systems (β=.271; P=.008) at the level of medical institutions (as big data technology) positively directly affected the transaction efficiency of medical services. Encryption security of web-based data (as big data technology) at the level of medical institutions, medical service capacity available for external use, real-time data of diagnosis and treatment services (as big data itself) at the level of medical institutions, and policies and regulations at the network level indirectly affected the transaction efficiency through network protection of the external link systems at the level of medical institutions. CONCLUSIONS This study found that big data technology, big data itself, and policy at the network and organizational levels interact with, and influence, each other to form the transaction efficiency of medical services. On the basis of the theory of neoclassical economics, the study highlighted the implications of big data resources for the emergence and development of endogenous MCNs.