Frank Romanelli

Dr. Frank Romanelli


Research Focus & Metrics

Academic Career Length

29Years (1998-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 September 2009 in American Journal of Pharmaceutical Education
Verified
Journal Article
Closed access
FRFrank Romanelli
Frank Romanelli
EBEleanora Bird
Eleanora Bird
MRMelody Ryan
Melody Ryan

1 September 2006 in American Journal of Pharmaceutical Education
Verified
Journal Article
Closed access
FRFrank Romanelli
Frank Romanelli
JCJeff Cain
Jeff Cain
KSKelly M. Smith
Kelly M. Smith
The concept of “emotional intelligence” has been extensively popularized in the lay press and corporate world as individuals purport the potential ability of emotional intelligence to predict vario...

16 January 2004 in Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy
Verified
Journal Article
Closed access
PDF file
FRFrank Romanelli
Frank Romanelli
KSKelly M. Smith
Kelly M. Smith
ATAlice C. Thornton
Alice C. Thornton
CPClaire Pomeroy
Claire Pomeroy

1 August 2004 in Current Pharmaceutical Design
Verified
Journal Article
Closed access
PDF file
FRFrank Romanelli
Frank Romanelli
KSKelly M. Smith
Kelly M. Smith
AHArdis Dee Hoven
Ardis Dee Hoven
Recent advances in the development of antiretrovirals have significantly extended life-spans and positively impacted morbidity of HIV-seropositive patients. While effective, antiretrovirals are associated with complex medication regimens, large pill burdens, and significant side effects which may impact quality of life. Researchers continue to examine various chemical entities in their search for agents with anti-HIV activity. Ideal agents would be efficacious, easily dosed and administered, inexpensive, and with few adverse effects. Chloroquine and its analog hydroxychloroquine are two inexpensive agents that are widely used for the treatment of malaria and have been shown to achieve some level of anti-HIV activity. The exact mechanism of chloroquine and hydroxychloroquines anti-HIV activity has not yet been discerned but may be related to effects on HIVs surface envelope glycoprotein 120. If found efficacious, both drugs would offer significant advantages to current therapy including a unique mechanism of action, lack of cross-resistance with other antiretrovirals, and low cost. Early and limited in vitro and in vivo data have demonstrated modest anti-HIV efficacy as indicated by measures of viral burden. Effects on CD4+ cell counts have not been as pronounced. It is premature to advocate the use of either of these agents in the management of routine HIV disease; however; the drugs should be further studied to determine their benefit in the treatment of patients who have exhausted all standard treatments. Larger, well-controlled trials are needed to discern the potential role of chloroquine and hydroxychloroquine in the management of HIV.

1 March 2009 in Journal of the American Pharmacists Association
Verified
Journal Article
Closed access
PDF file
FRFrank Romanelli
Frank Romanelli
KSKelly M. Smith
Kelly M. Smith

1 January 2020 in American Journal of Pharmaceutical Education
Verified
Journal Article
Closed access
PDF file
FRFrank Romanelli
Frank Romanelli
As practice evolves and scientific advancements are achieved the natural inclination for educators and administrators is to add new content to existing curricula. Often pre-existing curricula that may be outdated or no longer relevant may go un-checked leading to excessive coursework and program completion times. Faculty may also have emotional or other attachments to certain topics or content and that may serve as an additional or independent barrier to removing extraneous material. To avoid and curtail curricular hoarding of material it may be prudent to periodically engage in reviews of material assessing them for not only adherence to accreditation standards but also in terms of their on-going appropriateness and relevance to contemporary pharmacy practice. These exercises may be especially important today given the rate of information creation and dissemination in the modern digital age.