Knee osteoarthritis (KOA) is one of the deadliest forms of arthritis. If not treated at an early stage, it may lead to knee replacement. That is why early diagnosis of KOA is necessary for better treatment. Manually KOA detection is a time-consuming and error-prone task. Computerized methods play a vital role in accurate and speedy detection. Therefore, the classification and localization of the KOA method are proposed in this work using radiographic images. The two-dimensional radiograph images are converted into three-dimensional and LBP features are extracted having the dimension of N × 59 out of which the best features of N × 55 are selected using PCA. The deep features are also extracted using Alex-Net and Dark-net-53 with the dimensions of N × 1024 and N × 4096, respectively, where N represents the number of images. Then, N × 1000 features are selected individually from both models using PCA. Finally, the extracted features are fused serially with the dimension of N × 2055 and passed to the classifiers on a 10-fold cross-validation that provides an accuracy of 90.6% for the classification of KOA grades. The localization model is proposed with the combination of an open exchange neural network (ONNX) and YOLOv2 that is trained on the selected hyper-parameters. The proposed model provides 0.98 mAP for the localization of classified images. The experimental analysis proves that the presented framework provides better results as compared to existing works.

Diabetic retinopathy (DR) is a drastic disease. DR embarks on vision impairment when it is left undetected. In this article, learning-based techniques are presented for the segmentation and classification of DR lesions. The pre-trained Xception model is utilized for deep feature extraction in the segmentation phase. The extracted features are fed to Deeplabv3 for semantic segmentation. For the training of the segmentation model, an experiment is performed for the selection of the optimal hyperparameters that provided effective segmentation results in the testing phase. The multi-classification model is developed for feature extraction using the fully connected (FC) MatMul layer of efficient-net-b0 and pool-10 of the squeeze-net. The extracted features from both models are fused serially, having the dimension of N × 2020, amidst the best N × 1032 features chosen by applying the marine predictor algorithm (MPA). The multi-classification of the DR lesions into grades 0, 1, 2, and 3 is performed using neural network and KNN classifiers. The proposed method performance is validated on open access datasets such as DIARETDB1, e-ophtha-EX, IDRiD, and Messidor. The obtained results are better compared to those of the latest published works.

The possibility neutrosophic hypersoft set (pNHs-set) is a generalized version of the possibility neutrosophic soft set (pNs-set). It tackles the limitations of the pNs-set regarding the use of the multi-argument approximate function. This function maps sub-parametric tuples to a power set of the universe. It emphasizes the partitioning of each attribute into its respective attribute-valued set. These features make it a completely new mathematical tool for solving problems dealing with uncertainties. This makes the decision-making process more flexible and reliable. In this study, after characterizing some elementary notions and algebraic operations of the pNHs-set, Sanchez’s method (a classical approach for medical diagnosis) is modified under the pNHs-set environment. A modified algorithm is proposed for the medical diagnosis of heart diseases by integrating the concept of the pNHs-set and the modified Sanchez’s method. The authenticity of the proposed algorithm is evaluated through its implementation in a real-world scenario with real data from the Cleveland data set for heart diseases. The beneficial aspects of the proposed approach are evaluated through a structural comparison with some pertinent existing approaches.

Postpartum hemorrhage (PPH) is an obstetric emergency instigated by excessive blood loss which occurs frequently after the delivery. The PPH can result in volume depletion, hypovolemic shock, and anemia. This is particular condition is considered a major cause of maternal deaths around the globe. Presently, physicians utilize visual examination for calculating blood and fluid loss during delivery. Since the classical methods depend on expert knowledge and are inaccurate, automated machine learning based PPH diagnosis models are essential. In regard to this aspect, this study introduces an efficient oppositional binary crow search algorithm (OBCSA) with an optimal stacked auto encoder (OSAE) model, called OBCSA-OSAE for PPH prediction. The goal of the proposed OBCSA-OSAE technique is to detect and classify the presence or absence of PPH. The OBCSA-OSAE technique involves the design of OBCSA based feature selection (FS) methods to elect an optimum feature subset. Additionally, the OSAE based classification model is developed to include an effective parameter adjustment process utilizing Equilibrium Optimizer (EO). The performance validation of the OBCSA-OSAE technique is performed using the benchmark dataset. The experimental values pointed out the benefits of the OBCSA-OSAE approach in recent methods.

Multiple sclerosis (MS) is an autoimmune disease that causes mild to severe issues in the central nervous system (CNS). Early detection and treatment are necessary to reduce the harshness of the disease in individuals. The proposed work aims to implement a convolutional neural network (CNN) segmentation scheme to extract the MS lesion in a 2D brain MRI slice. To achieve a better MS detection, this work implemented the VGG-UNet scheme in which the pretrained VGG19 is considered as the encoder section. This scheme is tested on 30 patient images (600 images with dimension pixels), and the experimental outcome confirms that this scheme provides a better result compared to traditional UNet, SegNet, VGG-UNet, and VGG-SegNet. The experimental investigation implemented on axial, coronal and sagittal plane 2D slices of Flair modality confirms that this work provides a better value of Jaccard (>85%), Dice (>92%), and accuracy (>98%).