Gheorghe-Andrei Dan

Prof. Dr. Gheorghe-Andrei Dan

Carol Davila University of Medicine and Pharmacy Bucharest - Faculty of Medicine, Bucharest, Romania
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Research Focus & Metrics

Academic Career Length

35Years (1992-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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25 August 2023 in European Heart Journal
Verified
Journal Article
Closed access
RBRobert A Byrne
Robert A Byrne
XRXavier Rossello
Xavier Rossello
JCJ J Coughlan
J J Coughlan
EBEmanuele Barbato
Emanuele Barbato
CBColin Berry
Colin Berry
EGESC Scientific Document Group
ESC Scientific Document Group

22 September 2023 in European Heart Journal: Acute Cardiovascular Care
Verified
Journal Article
Closed access
RBRobert A Byrne
Robert A Byrne
XRXavier Rossello
Xavier Rossello
JCJ J Coughlan
J J Coughlan
EBEmanuele Barbato
Emanuele Barbato
CBColin Berry
Colin Berry
KZKatja Zeppenfeld
Katja Zeppenfeld

22 June 2023 in EP Europace
Verified
Journal Article
Open access
PDF file
TTTobias Toennis
Tobias Toennis
EBEmanuele Bertaglia
Emanuele Bertaglia
Axel BrandesAxel Brandes
Axel Brandes
Wolfgang DichtlWolfgang Dichtl
Wolfgang Dichtl
NFNina Fluschnik
Nina Fluschnik
PKPaulus Kirchhof
Paulus Kirchhof
Atrial high-rate episodes (AHRE) are atrial tachyarrhythmias detected by continuous rhythm monitoring by pacemakers, defibrillators, or implantable cardiac monitors. Atrial high-rate episodes occur in 10–30% of elderly patients without atrial fibrillation. However, it remains unclear whether the presence of these arrhythmias has therapeutic consequences. The presence of AHRE increases the risk of stroke compared with patients without AHRE. Oral anticoagulation would have the potential to reduce the risk of stroke in patients with AHRE but is also associated with a rate of major bleeding of ∼2%/year. The stroke rate in patients with AHRE appears to be lower than the stroke rate in patients with atrial fibrillation. Wearables like smart-watches will increase the absolute number of patients in whom atrial arrhythmias are detected. It remains unclear whether anticoagulation is effective and, equally important, safe in patients with AHRE. Two randomized clinical trials, NOAH-AFNET6 and ARTESiA, are expected to report soon. They will provide much-needed information on the efficacy and safety of oral anticoagulation in patients with AHRE.

1 September 2012 in American Heart Journal
Verified
Journal Article
Closed access
RMRobert J. Mentz
Robert J. Mentz
JKJuan-Carlos Kaski
Juan-Carlos Kaski
GDGheorghe-Andrei Dan
Gheorghe-Andrei Dan
SGSidney Goldstein
Sidney Goldstein
NSNorman Stockbridge
Norman Stockbridge
COChristopher M. O'COnnor
Christopher M. O'COnnor

25 September 2023 in European Journal of Internal Medicine
Verified
Journal Article
Closed access
Giuseppe BorianiGiuseppe Boriani
Giuseppe Boriani
NBNiccolo’ Bonini
Niccolo’ Bonini
MVMarco Vitolo
Marco Vitolo
DMDavide A Mei
Davide A Mei
Jacopo Francesco ImbertiJacopo Francesco Imberti
Jacopo Francesco Imberti
Gregory LipGregory Lip
Gregory Lip

13 September 2024 in EP Europace
Verified
Journal Article
Open access
PDF file
BGBulent Gorenek
Bulent Gorenek
AWAdrianus P Wijnmaalen
Adrianus P Wijnmaalen
Andreas GoetteAndreas Goette
Andreas Goette
GMGurbet Ozge Mert
Gurbet Ozge Mert
BPBradley Porter
Bradley Porter
OCOvidiu Chioncel
Ovidiu Chioncel
Patients presenting with or alerting emergency networks due to acute heart failure (AHF) form a diverse group with a plethora of symptoms, risks, comorbidities, and aetiologies. During AHF, there is an increased risk of destabilizing the functional substrate and modulatory adding to the risk of ventricular arrhythmias (VAs) already created by the structural substrate. New VAs during AHF have previously identified patients with higher intra-hospital and 60-day morbidity and mortality. Risk stratification and criteria/best time point for coronary intervention and implantable cardioverter defibrillator implantation, however, are still controversial topics in this difficult clinical setting. The characteristics and logistics of pre-hospital emergency medicine, as well as the density of centres capable of treating AHF and VAs, differ massively throughout Europe. Scientific guidelines provide clear recommendations for the management of arrhythmias in patients with chronic heart failure. However, the incidence, significance, and management of arrhythmias in patients with AHF have been less studied. This consensus paper aimed to address the identification and treatment of VAs that complicate the course of patients who have AHF, including cardiogenic shock.