Claudia Andrea Vargas

Claudia Andrea Vargas


Research Focus & Metrics

Academic Career Length

11Years (2016-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 December 2016 in International Journal of Morphology
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NONicolas E Ottone
Nicolas E Ottone
CVClaudia Andrea Vargas
Claudia Andrea Vargas
RFRamón Fuentes
Ramón Fuentes
MSMariano del Sol
Mariano del Sol
Walter Thiel developed the method that enables preservation of the body with natural colors in 1992. It consists in the application of an intravascular injection formula, and maintaining the corps submerged for a determinate period of time in the immersion solution in the pool. After immersion, it is possible to maintain the corps in a hermetically sealed container, thus avoiding dehydration outside the pool. The aim of this work was to review the Thiel method, searching all scientific articles describing this technique from its development point of view, and application in anatomy and morphology teaching, as well as in clinical and surgical practice. Most of these studies were carried out in Europe. We used PubMed, Ebsco and Embase databases with the terms "Thiel cadaver", "Thiel embalming", "Thiel embalming method" and we searched for papers that cited Thiel`s work. In comparison with methods commonly used with high concentrations of formaldehyde, this method lacks the emanation of noxious or irritating gases; gives the corps important passive joint mobility without stiffness; maintaining color, flexibility and tissue plasticity at a level equivalent to that of a living body. Furthermore, it allows vascular repletion at the capillary level. All this makes for great advantage over the formalinfixed and fresh material. Its multiple uses are applicable in anatomy teaching and research; teaching for undergraduates (prosection and dissection) and for training in surgical techniques for graduates and specialists (laparoscopies, arthroscopies, endoscopies).

29 January 2022 in Revista Brasileira de Ginecologia e Obstetrícia
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CLClaudia López-Ruiz
Claudia López-Ruiz
JOJerutsa Catalina Orjuela
Jerutsa Catalina Orjuela
DRDiego Fernando Rojas-Gualdrón
Diego Fernando Rojas-Gualdrón
MJMarcela Jimenez-Arango
Marcela Jimenez-Arango
JRJosé Fernando de Los Ríos
José Fernando de Los Ríos
CVClaudia Andrea Vargas
Claudia Andrea Vargas
Objective To summarize the available evidence of TAP Block in efficacy in laparoscopic or robotic hysterectomy. Data Sources We searched databases and gray literature for randomized controlled trials in which transversus abdominis plane (TAP) block was compared with placebo or with no treatment in patients who underwent laparoscopic or robot-assisted hysterectomy. Method of Study Selection Two researchers independently evaluated the eligibility of the selected articles. Tabulation, Integration, and Results Seven studies were selected, involving 518 patients. Early postoperative pain showed a difference in the mean mean difference (MD): - 1.17 (95% confidence interval [CI]: - 1.87–0.46) in pain scale scores (I2 = 68%), which was statistically significant in favor of using TAP block, but without clinical relevance; late postoperative pain: DM 0.001 (95%CI: - 0.43–0.44; I2 = 69%); opioid requirement: DM 0.36 (95%CI: - 0.94–1.68; I2 = 80%); and incidence of nausea and vomiting with a difference of 95%CI = - 0.11 (- 0.215–0.006) in favor of TAP. Conclusion With moderate strength of evidence, due to the high heterogeneity and imbalance in baseline characteristics among studies, the results indicate that TAP block should not be considered as a clinically relevant analgesic technique to improve postoperative pain in laparoscopic or robotic hysterectomy, despite statistical significance in early postoperative pain scale scores. Clinical Trial Number and Registry: PROSPERO ID - CRD42018103573. Objetivo Resumir as evidências disponíveis sobre a eficácia do bloqueio TAP em histerectomia laparoscópica ou robótica. Fontes de Dados Pesquisamos bancos de dados e literatura cinza por ensaios clínicos randomizados nos quais o bloqueio do plano transverso do abdome (TAP na sigla em inglês) foi comparado com placebo ou com nenhum tratamento em pacientes que foram submetidos a histerectomia laparoscópica ou assistida por robô. Métodos de Seleção de Estudos Dois pesquisadores avaliaram independentemente a elegibilidade dos artigos selecionados. Tabulação, Integração e Resultados Sete estudos foram selecionados envolvendo 518 pacientes. A dor pós-operatória precoce apresentou diferença nas médias (DM) de: -1 17 (intervalo de confiança [IC] de 95%: - 1 87–0 46) nos escores da escala de dor (I2 = 68%) o que foi estatisticamente significativo a favor do uso do bloqueio TAP mas sem relevância clínica; dor pós-operatória tardia: DM 0001 (IC95%: - 043–044; I2 = 69%); necessidade de opioides: DM 0 36 (95%CI: - 0 94–168; I2 = 80%); e incidência de náuseas e vômitos com diferença de 95% CI = - 011 (- 0215–0006) a favor do TAP. Conclusão Com moderada força de evidência devido à alta heterogeneidade e ao desequilíbrio nas características basais entre os estudos os resultados indicam que o bloqueio do TAP não deve ser considerado como uma técnica analgésica clinicamente relevante para melhorar a dor pós-operatória em histerectomia laparoscópica ou robótica apesar da significância estatística nas pontuações da escala de dor pós-operatória inicial. Número e Registro do Ensaio Clínico: PROSPERO ID - CRD42018103573. Received: 05 March 2021 Accepted: 30 August 2021 Article published online: 29 January 2022 © 2022. Federação Brasileira de Ginecologia e Obstetrícia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/) Thieme Revinter Publicações Ltda. Rua do Matoso 170, Rio de Janeiro, RJ, CEP 20270-135, Brazil

1 June 2018 in International Journal of Morphology
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Journal Article
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NONicolas E Ottone
Nicolas E Ottone
CVClaudia Andrea Vargas
Claudia Andrea Vargas
CVCarlos Veuthey
Carlos Veuthey
MSMariano Del Sol
Mariano Del Sol
RFRamón Fuentes
Ramón Fuentes
Plastination is an anatomical technique of cadaveric preservation that allows the preservation of anatomical pieces indefinitely, in dry and odorless form. It was created in 1978 by Gunther von Hagens, in Heidelberg, Germany. In particular, the sheet plastination technique, with epoxy resin, allows the generation of thin sections of various anatomical regions, allowing an accurate visualization of anatomical structures of difficult access through dissection or cadaveric exploration. The aim of this work was to present a new sheet plastination protocol with Biodur® E12/E1, which is faster in its implementation, applied, for the first time, in a rabbit head.

CVClaudia Andrea Vargas
Claudia Andrea Vargas
IGIris Guzmán-Guzmán
Iris Guzmán-Guzmán
Felipe Caamaño-NavarreteFelipe Caamaño-Navarrete
Felipe Caamaño-Navarrete
Daniel Jerez-MayorgaDaniel Jerez-Mayorga
Daniel Jerez-Mayorga
Luis Javier Chirosa RíosLuis Javier Chirosa Ríos
Luis Javier Chirosa Ríos
Pedro Delgado-FloodyPedro Delgado-Floody
Pedro Delgado-Floody
Background: Sleep is an important modulator of neuroendocrine function and glucose metabolism. Poor sleep quality is related to metabolic and endocrine alterations, including decreased glucose tolerance, decreased insulin sensitivity, and increased hunger and appetite. Objective: The aim of the present study was to determine the association between sleep quality with metabolic syndrome (MetS) markers, fitness and body fat of women with severe/morbid obesity. Methods: This cross-sectional study included 26 women with severe/morbid obesity. Fasting plasma glucose (FPG), high-density lipids (HDL-c), triglycerides (TGs), and the metabolic outcomes total cholesterol (Tc) and low-density lipids (LDL-c), systolic (SBP) and diastolic blood pressure (DBP), body composition and fitness were measured. Results: Poor sleep quality showed a positive association with body fat (%) ≥ 48.2 (OR; 8.39, 95% CI; 1.13–62.14, p = 0.037), morbid obesity (OR; 8.44, 95% CI; 1.15–66.0, p = 0.036), glucose ≥ 100 mg/dL (OR; 8.44, 95% CI; 1.15–66.0, p = 0.036) and relative handgrip strength ≤ 0.66 (OR; 12.2, 95% CI; 1.79–83.09, p = 0.011). Conclusion: sleep quality is associated with health markers in women with severe/morbid obesity.

Pedro Delgado-FloodyPedro Delgado-Floody
Pedro Delgado-Floody
Felipe Caamaño-NavarreteFelipe Caamaño-Navarrete
Felipe Caamaño-Navarrete
Luis Javier Chirosa RíosLuis Javier Chirosa Ríos
Luis Javier Chirosa Ríos
CMCristian Martínez
Cristian Martínez
CVClaudia Andrea Vargas
Claudia Andrea Vargas
IGIris Guzmán-Guzmán
Iris Guzmán-Guzmán
Background: Sleep quality is an important modulator of neuroendocrine function, as sleep problems are related to metabolic and endocrine alterations. Objective: The main objective was to determine the effects of an exercise training program on the sleep quality of severely obese patients with sleep problems. The secondary objective was to determine the relationship between fitness and anthropometric parameters with sleep quality scores. Methods: Thirty severely obese patients participated in 16 weeks of PA intervention (age: 39.30 ± 11.62 y, BMI: 42.75 ± 5.27 kg/m2). Subjective sleep quality, anthropometric parameters, and fitness (i.e., handgrip strength and cardiorespiratory fitness) were measured. Results: Two groups were defined as good sleepers (n = 15, 38.06 ± 12.26, men = 1) and bad sleepers (n = 15, 40.53 ± 11.23, men = 3). The good sleeper group reported improvement in cardiorespiratory fitness (61.33 ± 68.75 m vs. 635.33 ± 98.91 m, p = 0.003) and handgrip strength (29.63 ± 9.29 kg vs. 31.86 ± 7.17 kg, p = 0.049). The bad sleeper group improved their cardiorespiratory fitness (472.66 ± 99.7 m vs. 611.33 ± 148.75 m, p = 0.001). In terms of sleep quality dimensions, the bad sleeper group improved their subjective sleep quality (p < 0.001), sleep latency (p = 0.045), sleep duration (p = 0.031), and habitual sleep efficiency (p = 0.015). Comparing the changes in both groups (∆), there were differences in subjective sleep quality scores (∆ = 2.23 vs. ∆ = −3.90, p = 0.002), where 86.6% of the bad sleeper group improved sleep quality (p = 0.030). An increase in handgrip strength was correlated to improving sleep quality scores (r = −0.49, p = 0.050). Conclusions: Severely obese bad sleepers improved their subjective sleep quality, the components of sleep, and cardiorespiratory fitness through an exercise training program. Improvement in subjective sleep quality was linked to an increase in handgrip strength.

1 June 2017 in International Journal of Morphology
Verified
Journal Article
Open access
PDF file
NONicolas E Ottone
Nicolas E Ottone
CVClaudia Andrea Vargas
Claudia Andrea Vargas
MSMariano del Sol
Mariano del Sol
Omóplato" pasó a denominarse "escápula" pero aún no es oficial el cambio de nombre del músculo omohioideo, lo que se contrapone a una de las recomendaciones del Comité Federativo Internacional de Terminología anatómica que el término debe adaptarse al idioma vernáculo y su denominación debe concentrar la información y el papel descriptivo de la estructura en cuestión. Es por esto que hacemos un breve análisis del término M. omohyoideus (A04.2.04.003) Omohyoid en inglés y M. omohioideo en español. Se realizó