Jacques Marescaux is Professor of Surgery, Founder and Member of the Board of the Institute of Image-Guided Surgery (IHU Strasbourg), and President and Founder of IRCAD (1994), a uniquely structured institute advancing the field of surgery into the information era. In addition, he founded the European Institute for Telesurgery (EITS) as a training facility to disseminate the groundbreaking work at IRCAD. Over the last 27 years, this center has gained international acclaim by training more than 45,000 surgeons from 124 countries, and mirror IRCAD institutes have been created in Taiwan (2008) and Brazil (Sao Paulo’s state in 2011 and Rio de Janeiro in 2017). After the project in Beirut (Lebanon) in 2019, a fifth mirror Institute will be inaugurated in 2021 in Kigali (Rwanda) to train African surgeons in new minimally invasive surgical techniques. An additional IRCAD Institute will be created in Wuxi, near Shanghai, China in 2022. In addition, discussions are currently underway for the creation of a mirror institute in the United States and in India. In 2000, the IRCAD-EITS implemented a virtual online university, WeBSurg, available in six different languages. Jacques Marescaux and his team published up to 4800 national and international articles and communications. Jacques Marescaux was invited to deliver more than 450 speeches in many European, American, Japanese, and Chinese Universities or Schools of Medicine.