Wen-Hsin Chang

Dr. Wen-Hsin Chang

Department of Sports Medicine, Kaohsiung Medical University, Kaohsiung City, Taiwan
orcid

Research Focus & Metrics

Academic Career Length

20Years (2007-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 April 2011 in Metabolism
Verified
Journal Article
Closed access
Sing-Chung LiSing-Chung Li
Sing-Chung Li
YLYen-Hua Liu
Yen-Hua Liu
JLJen-Fang Liu
Jen-Fang Liu
WCWen-Hsin Chang
Wen-Hsin Chang
CCChiao-Ming Chen
Chiao-Ming Chen
CCC.-Y. Oliver Chen
C.-Y. Oliver Chen

22 June 2012 in European Journal of Nutrition
Verified
Journal Article
Closed access
PDF file
JLJen-Fang Liu
Jen-Fang Liu
YLYen-Hua Liu
Yen-Hua Liu
CCChiao-Ming Chen
Chiao-Ming Chen
WCWen-Hsin Chang
Wen-Hsin Chang
Oliver ChenOliver Chen
Oliver Chen

1 December 2010 in Journal of Applied Physiology
Verified
Journal Article
Closed access
WCWen-Hsin Chang
Wen-Hsin Chang
SHShene-Pin Hu
Shene-Pin Hu
YHYing-Fen Huang
Ying-Fen Huang
Tzu-Shao YehTzu-Shao Yeh
Tzu-Shao Yeh
JLJen-Fang Liu
Jen-Fang Liu
The aim of this study was to evaluate the effects of purple sweet potato leaves (PSPL) consumption on oxidative stress markers in a healthy, nontrained, young male population after completing a running exercise protocol. A crossover design was applied, with 15 subjects participating in a two-step dietary intervention period. Each subject was given a high- (PSPL group) or low-polyphenol (control group) diet for 7 days with a 14-day washout period. After each dietary intervention period, all subjects performed 1 h of treadmill running at a speed corresponding to 70% of each subject's individual maximal oxygen uptake (V̇o2max). Blood samples were taken before exercise and at 0, 1, and 3 h after exercise. Compared with the control group, PSPL consumption significantly increased plasma total polyphenols concentration and total antioxidant power (i.e., the ferric-reducing ability of plasma) in the PSPL group. The markers of oxidative damage, plasma TBARS and protein carbonyl, significantly decreased. Plasma IL-6 concentration also decreased. However, no significant difference was found in HSP72 levels between the two groups. These findings indicate that consuming a high-polyphenol diet for 7 days can modulate antioxidative status and decrease exercise-induced oxidative damage and pro-inflammatory cytokine secretion.

18 November 2009 in International Journal of Food Sciences and Nutrition
Verified
Journal Article
Closed access
PDF file
WCWen-Hsin Chang
Wen-Hsin Chang
JLJen-Fang Liu
Jen-Fang Liu
Cardiovascular disease (CVD) is the most important adult health problem in the world. Epidemiological studies and laboratory experiments have shown that fruit and vegetable consumption has protective effects against CVD. The purpose of the study was to investigate the effects of consumption of two kiwifruit per day on the lipid profile, antioxidants and markers of lipid peroxidation in hyperlipidemic adult men and women in Taiwan. Forty-three subjects who had hyperlipidemia, including 13 males and 30 females, participated in this study. They were asked to consume two kiwifruit per day for 8 weeks. Anthropometric measurements were made. Before the intervention and at 4 and 8 weeks of the intervention, fasting blood samples were analyzed for total cholesterol, triacylglycerol, low-density lipoprotein (LDL) cholesterol, and high-density lipoprotein cholesterol (HDL-C). Additionally vitamin E and vitamin C, the malondialdehyde + 4-hydroxy-2(E)-nonenal concentration, and the lag time of LDL oxidation were determined. No significant differences from baseline to 8 weeks of the intervention were detected for triacylglycerol, total cholesterol, or LDL cholesterol. However, after 8 weeks of consumption of kiwifruit, the HDL-C concentration was significantly increased and the LDL cholesterol/HDL-C ratio and total cholesterol/HDL-C ratio were significantly decreased. Vitamin C and vitamin E also increased significantly. In addition, the lag time of LDL oxidation and malondialdehyde + 4-hydroxy-2(E)-nonenal had significantly changed at 4 and 8 weeks during the kiwifruit intervention. Regular consumption of kiwifruit might exert beneficial effects on the antioxidative status and the risk factors for CVD in hyperlipidemic subjects.

TYTsung-Hsun Yang
Tsung-Hsun Yang
PCPo-Cheng Chen
Po-Cheng Chen
YLYun-Chung Lin
Yun-Chung Lin
YLYan-yuh Lee
Yan-yuh Lee
YTYu-Hsuan Tseng
Yu-Hsuan Tseng
Ho-Chang KuoHo-Chang Kuo
Ho-Chang Kuo
Background: Sweating and increased skin temperature caused by exercise can reduce physical activity and the willingness to exercise in adolescents with atopic dermatitis. This study was conducted to investigate the exercise load capacity of adolescents with atopic dermatitis and analyzed their exercise behavior and motivation. Methods: Adolescents with and without atopic dermatitis were assigned to the atopic dermatitis group and control group (n = 27 each). Both groups completed a cardiopulmonary exercise test and questionnaires to assess their exercise capacity, weekly exercise volume, exercise motivation, and self-efficacy, respectively. Results: The ratio of measured forced vital capacity to the predicted forced vital capacity and the peak oxygen consumption of the atopic dermatitis group were significantly lower than those of the control group. The Godin Leisure-Time Exercise Questionnaire scores of the atopic dermatitis group were significantly lower than those of the control group. As for the Behavioral Regulation in Exercise Questionnaire 2, the scores for the introjected and identified regulations of the atopic dermatitis group were significantly lower than those of the control group. Regarding the Multidimensional Self-Efficacy for Exercise Scale, the scheduling efficacy and total scores of the atopic dermatitis group were significantly lower than those of the control group. Conclusions: Adolescents with atopic dermatitis had lower peak exercise capacity and lower weekly exercise volume. Furthermore, they lacked the negative feelings toward inactivity and the self-confidence to plan regular exercise independently. The results of this study suggest that adolescents with atopic dermatitis should be encouraged to engage in regular indoor exercise.

CCChih-Wei Chang
Chih-Wei Chang
THTzu-Zung Huang
Tzu-Zung Huang
WCWen-Hsin Chang
Wen-Hsin Chang
YTYi-Chun Tseng
Yi-Chun Tseng
YWYu-Tse Wu
Yu-Tse Wu
MHMei-Chich Hsu
Mei-Chich Hsu
The purple mangosteen (Garcinia mangostana), known as the "queen of fruit," is widely consumed and unique not only because of its outstanding appearance and flavor but also its remarkable and diver...