The application of robotic systems is widespread in all fields of life and sport. Tennis ball collection robots have recently become popular because of their potential for saving time and energy and increasing the efficiency of training sessions. In this study, an unmanned and autonomous tennis ball collection robot was designed and produced that used LiDAR for 2D mapping of the environment and a single camera for detecting tennis balls. A novel method was used for the path planning and navigation of the robot. A fuzzy controller was designed for controlling the robot during the collection operation. The developed robot was tested, and it successfully detected 91% of the tennis balls and collected 83% of them.

Neovascular age-related macular degeneration (nAMD) is a leading cause of irreversible visual impairment in the elderly. The current management of nAMD is limited and involves regular intravitreal administration of anti-vascular endothelial growth factor (anti-VEGF). However, the effectiveness of these treatments is limited by overlapping and compensatory pathways leading to unresponsiveness to anti-VEGF treatments in a significant portion of nAMD patients. Therefore, a system view of pathways involved in pathophysiology of nAMD will have significant clinical value. The aim of this study was to identify proteins, miRNAs, long non-coding RNAs (lncRNAs), various metabolites, and single-nucleotide polymorphisms (SNPs) with a significant role in the pathogenesis of nAMD. To accomplish this goal, we conducted a multi-layer network analysis, which identified 30 key genes, six miRNAs, and four lncRNAs. We also found three key metabolites that are common with AMD, Alzheimer’s disease (AD) and schizophrenia. Moreover, we identified nine key SNPs and their related genes that are common among AMD, AD, schizophrenia, multiple sclerosis (MS), and Parkinson’s disease (PD). Thus, our findings suggest that there exists a connection between nAMD and the aforementioned neurodegenerative disorders. In addition, our study also demonstrates the effectiveness of using artificial intelligence, specifically the LSTM network, a fuzzy logic model, and genetic algorithms, to identify important metabolites in complex metabolic pathways to open new avenues for the design and/or repurposing of drugs for nAMD treatment.

The current study examines algorithmic approaches for analysis of multimodal attributes in localization-related epilepsy (LRE), specifically, their impact on the selection of patients for surgical consideration. Invasive electrographic data is excluded here to concentrate upon the localized anatomical landmarks and identified/initialized brain structures in volumetric MR images as well as initial clinical presentation and the varied elements of the seizure history, ictal semiology, risk and seizure-precipitating factors and physical findings in addition to several features of the neuropsychological profile including various parameters of cognition and both speech and memory lateralization. First, the imaging modality data is excluded and just clinical, electrographic and neuropsychological data are investigated. Afterward, the imaging data are investigated and a comparison between the prediction results of the two types of data is done. In the case of using non-imaging multimodal data, 56% and using imaging features, about 71% of correct outcome prediction was obtained.