Nanomedicines emerged from nanotechnology and have been introduced to bring advancements in treating multiple diseases. Nano-phytomedicines are synthesized from active phytoconstituents or plant extracts. Advancements in nanotechnology also help in the diagnosis, monitoring, control, and prevention of various diseases. The field of nanomedicine and the improvements of nanoparticles has been of keen interest in multiple industries, including pharmaceutics, diagnostics, electronics, communications, and cosmetics. In herbal medicines, these nanoparticles have several attractive properties that have brought them to the forefront in searching for novel drug delivery systems by enhancing efficacy, bioavailability, and target specificity. The current review investigated various therapeutic applications of different nano-phytopharmaceuticals in locomotor, dermal, reproductive, and urinary tract disorders to enhance bioavailability and efficacy of phytochemicals and herbal extracts in preclinical and in vitro studies. There is a lack of clinical and extensive preclinical studies. The research in this field is expanding but strong evidence on the efficacy of these nano-phytopharmaceuticals for human use is still limited. The long-term efficacy and safety of nano-phytopharmaceuticals must be ensured with priority before these materials emerge as common human therapeutics. Overall, this review provides up-to-date information on related contemporary research on nano-phytopharmaceuticals and nano-extracts in the fields of dermatological, urogenital, and locomotor disorders.
1 July 2020 in Asian Journal of Agriculture and Biology
This article aims to discuss the issues about Schistosoma japonicum infection in the Philippines based on the research findings of previous studies. This includes reviews about the nature of schistosomiasis, with emphasis on its effects on children. The review also discusses the mode of transmission of the parasite, etiology, and epidemiology, and relates these factors to the persistence of S. japonicum as a major health problem in the Philippines. The efforts, preventive measures, and recommended actions of the government are also mentioned and have been taken into consideration in strengthening the eradication measures against S. japonicum. This review further analyzes the risk factors associated with the infected individuals. Some measures and practices that may contribute to the prevention of S. japonicum infection are highlighted.