Purpose: This study compared the effects of a combination of soy peptide supplementation and exercise with those of exercise only, on the cognitive function of elderly adults. Patients and methods: This randomized, non-blinded, controlled clinical trial included 67 participants aged 60 years or more with non-cognitive dysfunction who were divided into two groups according to the intervention method: an exercise group (Ex group, n = 36) and an exercise plus nutrition group (Ex+Nt group, n = 31). The Ex group completed a memory training activity for 15 mins and aerobic exercise for 45 mins once a week for 90 days. The Ex+Nt group completed the same training plus received soy peptide for 90 days. The Mini-Mental Status Examination score, trail-making test A/B score, skeletal muscle mass index, grip strength, gait speed, and geriatric depression scale were measured at baseline and post intervention. For comparison between the pretest and posttest measurements to determine the intervention effects, a two-way analysis of variance was performed. The significance level was set at < 5%. Results: A two-way analysis of variance revealed significant time effects on trail-making test-A score, skeletal muscle index, grip strength, and gait speed in both groups. There were significant time x group interactions for greater increase in calculation score. Conclusion: A combination of exercise and soy peptide supplementation was effective in improving a portion of cognitive function.

SummaryBackgroundFalls are a serious problem among frail elderly and their prevention is an important health concern. We compared the frequency of falls among institutionalized frail elderly residents following different interventions: low-frequency exercise, vitamin D supplementation, and a combination of both.MethodsParticipants (N = 91) were residents in an institution for frail elderly (84.8 ± 8.8 years of age, 69 women). Participants were randomly assigned to one of four conditions: (1) the control group (n = 23) was provided three sessions per week of individualized exercise and usual care, (2) the low-exercise group (n = 22) was provided two sessions of individualized exercise per week, (3) the nutrition group (n = 23) was given oral vitamin D (900 IU/day), and (4) the combined group (n = 23) performed low-level exercise and received vitamin D supplementation.ResultsA two-way analysis of variance including interactions between experimental group and time indicated a clear benefit in the groups that received supplementation with vitamin D. A Cox proportional-hazard regression analysis, adjusted for sex and age, showed that compared to the control group, the combined group had a reduced risk of falls (hazard ratio: 0.28, 95% CI: 0.08–0.92, P < 0.05). The other groups did not significantly differ from controls.ConclusionThe intervention combining low-frequency exercise and vitamin D supplementation was effective for the reduction of falls among institutionalized frail elderly individuals

Introduction: Kinematic data obtained during a movement task by individuals with chronic low back pain seem to be related to pain-related fear. General kinesiophobia assessments, such as Tampa Scale for Kinesiophobia, are often used to assess pain-related fear. However, these questionnaires could suffer from a lack of sensitivity and do not measure the fear of specific movements. Objectives: The purpose of this study was to investigate whether the task-specific assessment of pain-related fear exhibits a closer association with trunk kinematics during lumbar flexion compared with the general kinesiophobia in individuals with chronic low back pain. Methods: We assessed pain-related factors, task-specific fear, and Tampa Scale for Kinesiophobia-11 scores of 51 company employees. The lumbar angle during a lumbar flexion task was recorded by 2 wireless Axivity Ax3 accelerometers attached to the subject's spinous process (L3) and sacral spine (S2). Only task-specific fear was evaluated after the lumbar flexion task. We calculated the maximum lumbar flexion angle (°) and the peak angular velocity of lumbar flexion/return from flexion (°/s²). We conducted a hierarchical multiple linear regression analysis to determine variance explained in lumbar flexion task performance by task-specific fear after controlling for demographic, pain, and general kinesiophobia. Results: The results showed that task-specific fear was associated with the peak angular velocity of lumbar return from flexion (R ² adj. = 0.36, P < 0.01) and lumbar flexion (R ² adj. = 0.3, P = 0.01). Discussion: Our results suggest that clinicians should consider the potential added value of task-specific fear assessment over the sole use of conventional kinesiophobia assessment.

• Depressive symptoms are associated with frailty in community-dwelling older adults. • AWGS’s new sarcopenia definition is not associated with depressive symptoms. • Depressive symptoms may be associated with J-CHS-defined frailty. • Among geriatric syndromes, only frailty may be associated with depressive symptoms.

Older people with chronic pain are at higher risk of developing sarcopenia. Central sensitization (CS) has been implicated in chronic pain among community-dwelling older adults. However, a relationship between CS and chronic pain with sarcopenia has not been established. This cross-sectional study aimed to clarify the relationship between chronic pain with sarcopenia or presarcopenia and CS among community-dwelling older adults. We assessed chronic pain and sarcopenia in 104 older adults participating in community health checks. We defined sarcopenia using the Asian Working Group for Sarcopenia (AWGS) consensus recommendations based on the following outcomes: low muscle mass, low muscle strength, and slow gait speed. Pain-related assessments included pain intensity, the Pain Catastrophizing Scale, the CS Inventory-9, the pressure pain threshold, the Tampa Scale of Kinesiophobia-11, and the EuroQol 5-dimension 5-level (EQ5D-5L). Chronic pain was defined by related symptoms within the month prior to the health check that had continued for ≥ 3 months and corresponded to a numerical rating scale score of ≥ 1 at the site of maximum pain. The prevalence of chronic pain was 43.3%. In addition, the prevalence of chronic pain with sarcopenia or presarcopenia was 29.8%. A logistic regression analysis revealed that the pressure pain threshold (odds ratio: 0.82, 95% CI: 0.95–1.02) and the EQ5D-5L (odds ratio: 0.58, 95% CI: 0.36–0.76) were significantly associated with the presence of chronic pain with sarcopenia or presarcopenia. Chronic pain with sarcopenia or presarcopenia was affected by central sensitization. Therefore, CS should be evaluated in the elderly.