Ray Taylor

Mr. Ray Taylor


Research Focus & Metrics

Academic Career Length

11Years (2016-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 May 2016 in Journal of Infection and Public Health
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Journal Article
Closed access
RTRay Taylor
Ray Taylor
PKPravin Kotian
Pravin Kotian
TWTravis Warren
Travis Warren
RPRekha Panchal
Rekha Panchal
SBSina Bavari
Sina Bavari
WSWilliam Sheridan
William Sheridan

10 June 2020 in Science Translational Medicine
Verified
Journal Article
Closed access
PDF file
SLSo-Yon Lim
So-Yon Lim
COChrista E. Osuna
Christa E. Osuna
KBKatharine Best
Katharine Best
RTRay Taylor
Ray Taylor
ECElsa Chen
Elsa Chen
JWJames B. Whitney
James B. Whitney
Galidesivir, a broad-spectrum direct-acting adenosine analog antiviral drug, abrogates viremia in rhesus macaques infected with Zika virus.

21 December 2021 in Viruses
Verified
Journal Article
Open access
PDF file
RTRay Taylor
Ray Taylor
RBRichard Bowen
Richard Bowen
JDJim Demarest
Jim Demarest
MDMichael DeSpirito
Michael DeSpirito
AHAirn Hartwig
Airn Hartwig
YBYarlagadda S. Babu
Yarlagadda S. Babu
Coronavirus disease 2019 (COVID-19) has claimed the lives of millions of people worldwide since it first emerged. The impact of the COVID-19 pandemic on public health and the global economy has highlighted the medical need for the development of broadly acting interventions against emerging viral threats. Galidesivir is a broad-spectrum antiviral compound with demonstrated in vitro and in vivo efficacy against several RNA viruses of public health concern, including those causing yellow fever, Ebola, Marburg, and Rift Valley fever. In vitro studies have shown that the antiviral activity of galidesivir also extends to coronaviruses. Herein, we describe the efficacy of galidesivir in the Syrian golden hamster model of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Treatment with galidesivir reduced lung pathology in infected animals compared with untreated controls when treatment was initiated 24 h prior to infection. These results add to the evidence of the applicability of galidesivir as a potential medical intervention for a range of acute viral illnesses, including coronaviruses.

19 February 2022 in Clinical Pharmacology in Drug Development
Verified
Journal Article
Closed access
PDF file
AMAmanda Mathis
Amanda Mathis
DCDavid Collins
David Collins
SDSylvia Dobo
Sylvia Dobo
DWDennis M. Walling
Dennis M. Walling
WSWilliam P. Sheridan
William P. Sheridan
RTRay Taylor
Ray Taylor