The aim of the present review article is to establish a systematic review to describe the role of various salivary components such as pH, buffering capacity, proteins, electrolyte, antioxidant, enzymes, and minerals in occurrence and initiation of dental caries in participants with and without dental caries. An electronic search was conducted in the PubMed, Scopus, Web of Science, and Google Scholar databases. The MESH terms (Medical Subject Headings) were “dental caries susceptibility,” “caries risk assessment, ”Salivary Biomarker,” “saliva,” “Proteins,” “electrolytes,” “biomarker,” “Anti-oxidant’s.” The database search was limited to the studies published between 2008 and 2018 and only human studies were included. Furthermore, the STROBE criteria checklist was used to analyze the studies which had to be included in the systematic review. A total of 150 articles were retrieved through electronic database. After evaluating the title, abstract, and full text of these articles, only 11 were selected for the present systematic review. However, two articles were excluded because they were classified as high risk of bias according to the STROBE criteria. Out of 9 studies selected, 5 were classified as low-risk bias and 4 were classified as moderate-risk bias. Based on the results of the systematic review, out of 11 studies, 7 found to have a statistically significant difference between individuals with and without caries experience. Hence, it can be concluded that there is an association between various components of saliva and dental caries.

The study evaluated the antibacterial effects of dental restorations such as nano-hybrid composite (Empress), a glass ionomer cement (GIC Gold label Type 9) and silver amalgam against Streptococcus mutans. A modified bacterial suspension within the material assay was used to study the antibacterial effects. A volume of 20 μl of bacterial suspensions were placed in a narrow conical cavity within the materials. They were incubated for 0, 3, 6, 12, 24, and 48 h at 37°C. After the incubation period, the number of viable cells in the suspension was evaluated. In liquid culture assay, growth inhibition was measured at A600 nm up to 6 h in bacterial suspensions treated with the eluates of the restorative materials. Kruskal–Wallis test and Mann–Whitney's test were performed to determine the significant differences between the control and restorative materials for given incubation periods at 5% level of significance (P < 0.05) After 6 h of incubation, all restorative materials showed an inhibitory effect when compared to the controls. Silver amalgam showed the highest inhibition, followed by GIC Type 9 and composite. Silver amalgam showed marked inhibition after 2 h in comparison to the other material groups. These techniques employed to study the antibacterial effects showed that the silver amalgam had the pronounced inhibitory effect followed by GIC and composite. Further research on these aspects is necessary to determine whether the material can prevent secondary caries formation.

Introduction: The key for long-term success in root canal therapy is the effective debridement with chemical irrigants before obturation. The purpose of this study was to compare the antimicrobial effect of sodium hypochlorite and chlorhexidine along with activation using sonic and an ultrasonic device in teeth when used in teeth infected with Enterococcus faecalis. Material and Method: A total of 90 single rooted mandibular premolar were infected with E. faecalis and placed in the incubator for 24 hours. The specimens were divided into six groups as follows: Group I: positive control; Group II: negative control; Group III: sodium hypochlorite + passive ultrasonic activation for 20, 40, and 60 seconds; Group IV: chlorhexidine + passive ultrasonic activation; Group V: sodium hypochlorite + endoactivator; and Group VI: chlorhexidine + endoactivator activation. After disinfection, dentinal shavings were collected using H file and subcultured in brain heart infusion agar (BHI) broth further streaked in brain heart agar plates to check the colony counting. Result: Bonferroni post hoc test was done to compare the significant difference between different experimental groups. Group III showed a significant difference in the antimicrobial activity compared to Group IV, V, and VI with P < 0.05. One-way analysis of variance (ANOVA) analysis was done to analyze the intergroup comparison of the bacterial count at various time intervals (20, 40, and 60 seconds). It was observed that there was a statistically significant difference with P < 0.01 between the time interval of different experimental groups. Conclusion: Within the limitation of this study, sodium hypochlorite along with passive ultrasonic irrigation showed a reduction in E. faecalis count compared to the other irrigating protocols used in the study and the results were statistically significant.

Aim: The effective delivery of irrigants into the inaccessible areas of the root canal system is the prerequisite for a proper disinfection of the root canal system. Numerous activation devices that can provide effective delivery of the irrigant and aid in the success of the root canal treatment are available. The activation of irrigants has claimed to be effective in in vitro and clinical trials. Hence, the present systematic review aims to analyze the effect of irrigants and irrigating devices in disinfecting the root canal system. Materials and Methods: A literature search was undertaken in PubMed, Cochrane, Web of Science, and Scopus databases. The inclusion criteria included clinical trials, both in vivo and ex vivo. The exclusion criteria included animal studies, textbooks, review articles, and case reports. The patients who required endodontic treatment along with the activation of irrigants were chosen as participants for the review. Result: The search strategy screened around 132 articles, out of which only 10 were selected for the present systematic review. The risk of bias was calculated based on the following scores: 3, high; 2, moderate; and 1, low. In the present systematic review, four articles were categorized into low-risk bias, three articles were classified as moderate risk, and three articles belonged to the high-risk category. Conclusion: The present systematic review concluded that the use of a mechanical activation device along with the irrigant will help in better removal of the smear layer and debris from the root canal system, improving the cleanliness and helping achieve more successful endodontic treatment.

O two groups: Group I (n = 32): micro hybrid composite Te-ecoconom Plus (IvoclarVivadent) and Group II (n = 32): nanohybrid composite Beautifil II (Shofu Inc.). The two groups were further subdivided on the basis of polishing system used into four subgroups. The control subgroup (n = 8) did not receive any finishing or polishing. Subgroup A (n = 8)—Sof-Lex XT (3M ESPE). Subgroup B (n = 8)—OneGloss (Shofu Inc.). Subgroup C (n = 8)—Super-Snap X-TREME Technique Kit (Shofu Inc.). A surface profilometer was used to evaluate the surface roughness following the finishing and polishing processes. The measured value was analyzed using independent sample t test. The findings were computed using SPSS Software version 20. Results: On comparing the composites and polishing systems using independent sample t test, it was found that Beautifil II group using Super-Snap X-TREME polishing system showed a significant difference when compared to the Beautifil II group using OneGloss system and the Te-econom Plus group using the Super-Snap X-TREME system generating P value of 0.009 and 0.004, respectively, which is <0.05 hence considered to be statistically significant. Conclusion: Within the limitations of this study, the nanohybrid composite resin showed a better polishability as compared with the micro hybrid composite. The three polishing system used significantly influenced the surface roughness with Super-Snap X-TREME, Sof-Lex multistep polishing system producing a smoother surface compared to OneGloss one step polishing system....