George Varvounis was born in Alexandria, Egypt, 1953. B.Sc. (Hons) in Chemistry and Biochemistry (1977) Polytechnic of Central London, M.Sc. in Applied Heterocyclic Chemistry (1979) and Ph.D. in Organic Chemistry (1982), University of Salford. Appointed Lecturer at the University of Ioannina, Greece (1982), Assistant Professor (1990), Associate Professor (2001) and Full Professor (2012). Sabbatical leave at King’s College London and Salford University. Research interests include the synthesis of pharmaceutically interesting heterocyclic compounds, such as pyrroles and pyrrolobenzodiazepines, also benzo and naphtho fused bi- and tricycles containing, N, O and S that involve reactions such as oxidative cyclization, 1,3-dipolar cycloaddition and tele nucleophilic substitution, and the intermediacy of o-quinone methides and o-quinone nitrosomethides intermediates.