Through theoretical analysis, this paper preliminarily puts forward the optimization design method of a mix proportion large stone permeable mixture based on target voidage. The optimized large stone permeable mixture is abbreviated as OLSPM (optimization large stone permeable mixture). On this basis, the asphalt content was verified by leakage analysis experiment, and the molding method was determined by comparing the volume parameter changes and the appearance of the specimen in the molding process of both a Marshall compaction test and rotary compaction test. The final experimental analysis results show that the asphalt content calculated by this method can meet the technical requirements of leakage loss. The rotary compaction method is the suitable molding method for indoor cylindrical specimens of OLSPM, and the voidage is used as the index to control the compac-tion times of OLSPM. Under the same voidage, OLSPM-25 has more fine aggregates and thus leads to a relatively large amount of asphalt. In addition, the content of 4.75–19 mm coarse aggregate in its coarse aggregate is also higher than that of LSPM-25.