Deepti Diwan

Dr. Deepti Diwan

Washington University School of Medicine
orcid

Research Focus & Metrics

Academic Career Length

13Years (2014-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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6 September 2022 in Microbiological Research
Verified
Journal Article
Closed access
Deepti DiwanDeepti Diwan
Deepti Diwan
MRMahtab Rashid
Mahtab Rashid
AVAnukool Vaishnav
Anukool Vaishnav

19 December 2022 in Nanofabrication
Verified
Journal Article
Open access
PDF file
SBSaroj Bala
Saroj Bala
Minaxi SharmaMinaxi Sharma
Minaxi Sharma
KDKavya Dashora
Kavya Dashora
SSSaba Siddiqui
Saba Siddiqui
Deepti DiwanDeepti Diwan
Deepti Diwan
Manikant TripathiManikant Tripathi
Manikant Tripathi
The global energy crisis affects all of us. With a growing global population and finite fossil fuel supplies, we must find new energy sources. Alternative energy sources must be prioritized. Biofuels like biodiesel, biohydrogen, biomethanol, and bioethanol have come a long way in recent decades. These alternative fuels are from low-cost, renewable sources like algal, microbial, and plant biomass. Several governments, including India, are improving their renewable energy production capabilities. The main obstacles to rapid biofuel adoption are time and cost. For biofuel to truly become a viable alternative to fossil fuels, nanotechnology has recently provided the much-needed impetus. Nanomaterials' unique structural behavior, such as small size (nanoscale size), has increased their use in biofuel production. It improves efficiency and reduces the time required to convert waste into biofuels. This review addresses the latest information on various types of nanoparticles, and challenges faced and the future prospects of emerging applications of nanoparticles in biofuel production.

19 February 2014 in BMC Genomics
Verified
Journal Article
Open access
PDF file
Deepti DiwanDeepti Diwan
Deepti Diwan
SKShun Komazaki
Shun Komazaki
Miho SuzukiMiho Suzuki
Miho Suzuki
NNNaoto Nemoto
Naoto Nemoto
TATakuyo Aita
Takuyo Aita
KNKoichi Nishigaki
Koichi Nishigaki
Even in the age of next-generation sequencing (NGS), it has been unclear whether or not cells within a single organism have systematically distinctive genomes. Resolving this question, one of the most basic biological problems associated with DNA mutation rates, can assist efforts to elucidate essential mechanisms of cancer.

18 January 2017 in Molecules
Verified
Journal Article
Open access
PDF file
Deepti DiwanDeepti Diwan
Deepti Diwan
KSKohei Shinkai
Kohei Shinkai
TTToshihiro Tetsuka
Toshihiro Tetsuka
BCBin Cao
Bin Cao
HAHidenao Arai
Hidenao Arai
KMKoji Matsuoka
Koji Matsuoka
Protein–carbohydrate interactions exhibit myriad intracellular recognition events, so understanding and investigating their specific interaction with high selectivity and strength are of crucial importance. In order to examine the effect of multivalent binding on the specificity of protein–carbohydrate interactions, we synthesized mannose glycosides as a novel type of glycosylated monomer and glycopolymers of polyacrylamide derivatives with α-mannose (α-Man) by radical polymerization and monitored their strength of interaction with concanavalin A (Con A) by surface plasmon resonance (SPR) detection. In a quantitative test using the Con A-immobilized sensor surface, the kinetic affinity for the synthesized polymers, 8a (KD = 3.3 × 10−6 M) and 8b (KD = 5.3 × 10−5 M), were concentration-dependent, showing strong, specific molecular recognition abilities with lectin. Our study showed the enhancement in recognition specificity for multivalent saccharides, which is often mediated by cell surface carbohydrate-binding proteins that exhibit weak affinity and broad specificity for the individual ligands.