Hao Dong

Dr. Hao Dong


Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 March 2022 in Toxins
Verified
Journal Article
Open access
PDF file
LQLinkai Qu
Linkai Qu
LWLei Wang
Lei Wang
HJHao Ji
Hao Ji
YFYimeng Fang
Yimeng Fang
PLPengyu Lei
Pengyu Lei
HDHao Dong
Hao Dong
Food safety is related to the national economy and people’s livelihood. Fumonisins are widely found in animal feed, feed raw materials, and human food. This can not only cause economic losses in animal husbandry but can also have carcinogenicity or teratogenicity and can be left in animal meat, eggs, and milk which may enter the human body and pose a serious threat to human health. Although there are many strategies to prevent fumonisins from entering the food chain, the traditional physical and chemical methods of mycotoxin removal have some disadvantages, such as an unstable effect, large nutrient loss, impact on the palatability of feed, and difficulty in mass production. As a safe, efficient, and environmentally friendly detoxification technology, biological detoxification attracts more and more attention from researchers and is gradually becoming an accepted technique. This work summarizes the toxic mechanism of fumonisins and highlights the advances of fumonisins in the detoxification of biological antioxidants, antagonistic microorganisms, and degradation mechanisms. Finally, the future challenges and focus of the biological control and degradation of fumonisins are discussed.

1 December 2021 in Journal of Veterinary Research
Verified
Journal Article
Open access
PDF file
YCYanhui Chen
Yanhui Chen
RARuth Afumba
Ruth Afumba
FPFusheng Pang
Fusheng Pang
RYRongxin Yuan
Rongxin Yuan
HDHao Dong
Hao Dong
Derzsy’s disease and Muscovy duck parvovirus disease have become common diseases in waterfowl culture in the world and their potential to cause harm has risen. The causative agents are goose parvovirus (GPV) and Muscovy duck parvovirus (MDPV), which can provoke similar clinical symptoms and high mortality and morbidity rates. In recent years, duck short beak and dwarfism syndrome has been prevalent in the Cherry Valley duck population in eastern China. It is characterised by the physical signs for which it is named. Although the mortality rate is low, it causes stunting and weight loss, which have caused serious economic losses to the waterfowl industry. The virus that causes this disease was named novel goose parvovirus (NGPV). This article summarises the latest research on the genetic relationships of the three parvoviruses, and reviews the aetiology, epidemiology, and necropsy characteristics in infected ducks, in order to facilitate further study.

1 July 2021 in Research in Veterinary Science
Verified
Journal Article
Closed access
YYYu-Qing Yan
Yu-Qing Yan
LJLi-Bo Jin
Li-Bo Jin
YWYu Wang
Yu Wang
SLSong-Yan Lu
Song-Yan Lu
YPYi-Feng Pei
Yi-Feng Pei
GHGuixue Hu
Guixue Hu

15 November 2023 in Aquaculture
Verified
Journal Article
Closed access
JGJin-Shuo Gong
Jin-Shuo Gong
YWYing-Da Wang
Ying-Da Wang
YJyanlong jiang
yanlong jiang
DZDi Zhang
Di Zhang
YCYa-Nan Cai
Ya-Nan Cai
HDHao Dong
Hao Dong

26 June 2024 in Frontiers in Cellular and Infection Microbiology
Verified
Journal Article
Open access
PDF file
HZHanjia Zhang
Hanjia Zhang
XLXuanyi Liu
Xuanyi Liu
JSJiuming Shi
Jiuming Shi
XSXuan Su
Xuan Su
JXJiayuan Xie
Jiayuan Xie
HDHao Dong
Hao Dong
Exosomes are extracelluar vesicles that facilitate intercellular communication and are pivotal in post-transcriptional regulation within cellular gene regulatory networks, impacting pathogen dynamics. These vesicles serve as crucial regulators of immune responses, mediating cellular interactions and enabling the introduction of viral pathogenic regions into host cells. Exosomes released from virus-infected cells harbor diverse microRNAs (miRNAs), which can be transferred to recipient cells, thereby modulating virus infection. This transfer is a critical element in the molecular interplay mediated by exosomes. Additionally, the endosomal sorting complex required for transport (ESCRT) within exosomes plays a vital role in virus infection, with ESCRT components binding to viral proteins to facilitate virus budding. This review elucidates the roles of exosomes and their constituents in the invasion of host cells by viruses, aiming to shed new light on the regulation of viral transmission via exosomes.

1 January 2023
Verified
Journal Article
Closed access
JLJun-Ting Liu
Jun-Ting Liu
YCYan-Hui Chen
Yan-Hui Chen
YPYi-Feng Pei
Yi-Feng Pei
QYQian Yu
Qian Yu
RARuth Afumba
Ruth Afumba
HDHao Dong
Hao Dong