Glaucoma is one of the ophthalmological diseases that frequently causes loss of vision in today’s society. Previous studies assess which anatomical parameters of the optic nerve can be predictive of glaucomatous damage, but to date there is no test that by itself has sufficient sensitivity and specificity to diagnose this disease. This work provides a public dataset with medical data and fundus images of both eyes of the same patient. Segmentations of the cup and optic disc, as well as the labeling of the patients based on the evaluation of clinical data are also provided. The dataset has been tested with a neural network to classify healthy and glaucoma patients. Specifically, the ResNet-50 has been used as the basis to classify patients using information from each eye independently as well as using the joint information from both eyes of each patient. Results provide the baseline metrics, with the aim of promoting research in the early detection of glaucoma based on the joint analysis of both eyes of the same patient.

This paper deals with the theory and applications of spatially-variant discrete mathematical morphology. We review and formalize the definition of spatially variant dilation/erosion and opening/closing for binary and gray-level images using exclusively the structuring function, without resorting to complement. This theoretical framework allows to build morphological operators whose structuring elements can locally adapt their shape and orientation across the dominant direction of the structures in the image. The shape and orientation of the structuring element at each pixel are extracted from the image under study: the orientation is given by means of a diffusion process of the average square gradient field, which regularizes and extends the orientation information from the edges of the objects to the homogeneous areas of the image; and the shape of the orientated structuring elements can be linear or it can be given by the distance to relevant edges of the objects. The proposed filters are used on binary and gray-level images for enhancement of anisotropic features such as coherent, flow-like structures. Results of spatially-variant erosions/dilations and openings/closings-based filters prove the validity of this theoretical sound and novel approach.

The ability of tapered leaky-wave antennas (LWAs) to synthesize directive radiation diagrams with suppression of the radiation in prescribed angular regions is studied in this work. The synthesis is based on an iterative Fourier technique that has been adapted for the case of LWAs, taking into account that the far field is related to the antenna illumination through an inverse Fourier transform. Results show that the simultaneous tapering of both phase and leakage constants of the leaky mode allow to obtain wide and deep radiation nulls while maintaining the high-gain scanning pattern of LWAs. The limitations of this unconventional tapering technique are also reported, and a practical design is validated with simulations.

Glaucoma is a group of eye conditions that damage the optic nerve, the health of which is vital for good eyesight. This damage is often caused by higher-than-normal pressure in the eye. In the past few years, the applications of artificial intelligence and data science have increased rapidly in medicine especially in imaging applications. In particular, deep learning tools have been successfully applied obtaining, in some cases, results superior to those obtained by humans. In this article, we present a soft novel ensemble model based on the K-NN algorithm, that combines the probability of class membership obtained by several deep learning models. In this research, three models of different nature (CNN, CapsNets and Convolutional Autoencoders) have been selected searching for diversity. The latent space of these models are combined using the local information provided by the true sample labels and the K-NN algorithm is applied to determine the final decision. The results obtained on two different datasets of retinal images show that the proposed ensemble model improves the diagnosis capabilities for both the individual models and the state-of-the-art results.