An essential work in natural language processing is the Multi-Label Text Classification (MLTC). The purpose of the MLTC is to assign multiple labels to each document. Traditional text classification methods, such as machine learning usually involve data scattering and failure to discover relationships between data. With the development of deep learning algorithms, many authors have used deep learning in MLTC. In this paper, a novel model called Spotted Hyena Optimizer (SHO)-Long Short-Term Memory (SHO-LSTM) for MLTC based on LSTM network and SHO algorithm is proposed. In the LSTM network, the Skip-gram method is used to embed words into the vector space. The new model uses the SHO algorithm to optimize the initial weight of the LSTM network. Adjusting the weight matrix in LSTM is a major challenge. If the weight of the neurons to be accurate, then the accuracy of the output will be higher. The SHO algorithm is a population-based meta-heuristic algorithm that works based on the mass hunting behavior of spotted hyenas. In this algorithm, each solution of the problem is coded as a hyena. Then the hyenas are approached to the optimal answer by following the hyena of the leader. Four datasets are used (RCV1-v2, EUR-Lex, Reuters-21578, and Bookmarks) to evaluate the proposed model. The assessments demonstrate that the proposed model has a higher accuracy rate than LSTM, Genetic Algorithm-LSTM (GA-LSTM), Particle Swarm Optimization-LSTM (PSO-LSTM), Artificial Bee Colony-LSTM (ABC-LSTM), Harmony Algorithm Search-LSTM (HAS-LSTM), and Differential Evolution-LSTM (DE-LSTM). The improvement of SHO-LSTM model accuracy for four datasets compared to LSTM is 7.52%, 7.12%, 1.92%, and 4.90%, respectively.

The production of blood cells is affected by leukemia, a type of bone marrow cancer or blood cancer. Deoxyribonucleic acid (DNA) is related to immature cells, particularly white cells, and is damaged in various ways in this disease. When a radiologist is involved in diagnosing acute leukemia cells, the diagnosis is time consuming and needs to provide better accuracy. For this purpose, many types of research have been conducted for the automatic diagnosis of acute leukemia. However, these studies have low detection speed and accuracy. Machine learning and artificial intelligence techniques are now playing an essential role in medical sciences, particularly in detecting and classifying leukemic cells. These methods assist doctors in detecting diseases earlier, reducing their workload and the possibility of errors. This research aims to design a deep learning model with a customized architecture for detecting acute leukemia using images of lymphocytes and monocytes. This study presents a novel dataset containing images of Acute Lymphoblastic Leukemia (ALL) and Acute Myeloid Leukemia (AML). The new dataset has been created with the assistance of various experts to help the scientific community in its efforts to incorporate machine learning techniques into medical research. Increasing the scale of the dataset is achieved with a Generative Adversarial Network (GAN). The proposed CNN model based on the Tversky loss function includes six convolution layers, four dense layers, and a Softmax activation function for the classification of acute leukemia images. The proposed model achieved a 99% accuracy rate in diagnosing acute leukemia types, including ALL and AML. Compared to previous research, the proposed network provides a promising performance in terms of speed and accuracy; and based on the results, the proposed model can be used to assist doctors and specialists in practical applications.