Pin-Ru Chen

Mr. Pin-Ru Chen


Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 November 2021 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
PCPin-Ru Chen
Pin-Ru Chen
YLYu Ching Lin
Yu Ching Lin
BPBetty Chien-Jung Pai
Betty Chien-Jung Pai
HTHsiao-Jung Tseng
Hsiao-Jung Tseng
Lun-Jou LoLun-Jou Lo
Lun-Jou Lo
邦昀(Pang-Yun) 周(Chou)邦昀(Pang-Yun) 周(Chou)
邦昀(Pang-Yun) 周(Chou)
(1) Background: Continuing to observe the grafted bone mineral density (BMD) is essential to ensure the success of alveolar bone grafting (ABG) in patients with cleft lip and palate. This study elaborates on three methods that can be used to evaluate the progressive BMD. (2) Methods: Forty patients with unilateral or bilateral clefts receiving ABG were enrolled. Cone beam computed tomography (CBCT) scans were taken at 6 months (T1) and 2 years (T2) postoperatively. In CBCT, measurements were obtained on three different planes using the circle located 1 mm from the adjacent teeth (Method A), the largest circle within the defect (Method B), or the central circle with a diameter of 2 mm (Method C). The BMD was the average density of the three planes and was adjusted by pogonion density. Bland–Altman plots were used to evaluate the agreement of each method. Inter-rater reliability was confirmed by the intraclass correlation coefficient (ICC). (3) Results: For Method A, B, and C, the mean-adjusted BMD (BMD/pogonion density, BMDa) was 17.44%, 17.88%, and 17.69%, respectively, at T1 (p = 0.495), and 22.51%, 22.87%, and 22.74%, respectively, at T2 (p = 0.690); the density enhancement rates were 40.54%, 38.92%, and 43.15% (p = 0.382). Significant differences between the BMDa at T1 and T2 were observed (p < 0.001, <0.001, and 0.001, for Method A, B, and C, respectively). The volume of the grafted tissue remained stable during T1 and T2, and no significant correlation between density enhancement rate and volume loss was observed. (4) Conclusions: A significant increase in the BMD of grafted tissue was observed in the 2-year postoperative follow-up. The three methods for measuring BMDa via CBCT can be applied in post-ABG evaluations.

8 October 2025 in Children
Verified
Journal Article
Open access
PDF file
JTJunior Tu
Junior Tu
AMAmber Paige McCranie
Amber Paige McCranie
MDMuhammad Daiem
Muhammad Daiem
WLWei-Lung Lin
Wei-Lung Lin
PCPin-Ru Chen
Pin-Ru Chen
DLDaniel Lonic
Daniel Lonic
Background: This study explored how Taiwanese schoolchildren perceive the appearance of their peers with and without cleft lip and palate (CLP) and whether this perception affects social interactions. We specifically focused on early adolescents with surgically repaired CLP to assess the impact of residual craniofacial deformities. Methods: A cross-sectional design was used, analyzing three-dimensional (3D) surface images of twenty patients with repaired CLP and five without. A total of 91 schoolchildren (40 with CLP, 51 without) served as raters. Participants used a Likert scale to rate images on facial appearance and perceived social acceptance. The study also measured the reliability of its questionnaires using Cronbach’s alpha. Results: All participants successfully differentiated between images of children with and without CLP, though non-cleft participants had significantly better distinguishing abilities. Non-cleft raters consistently gave more positive appearance ratings to non-cleft images, a pattern less evident among cleft raters. While differences in awareness and acceptance between the two groups were not statistically significant, over half of all responses regarding social interaction were neutral. The questionnaires demonstrated high reliability, with Cronbach’s alpha values greater than 0.85. Conclusions: Despite the ability to perceive residual craniofacial differences, appearance alone did not significantly affect social interactions for early adolescent children with surgically repaired CLP in Taiwan. This suggests that other factors may play a larger role in social dynamics within this population.