Vassiliki Magafa

Dr. Vassiliki Magafa

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Biography

AREAS OF RESEARCH INTEREST Synthetic preparation of biologically active peptide analogs (AII, OT, VP, LH-RH, SP, NT, CRH, etc.) in liquid and solid phase, and study of structure–activity relationships. Development of methods for synthesizing peptides with multiple disulfide bonds. Development of methods for synthesizing hybrid peptides with natural antioxidant molecules. Synthesis of carbo(hetero)cyclic biomimetic structures with suitable features for incorporation into peptide sequences and the development of hybrid (semi-mimetic) peptides. Study of biologically active peptides using NMR spectroscopy. Synthetic preparation of cysteine-containing peptides and their complexes with heavy metals, and analysis using various spectroscopic techniques such as IR, Far-IR, CD, UV-Vis, and ^1H and ^13C NMR. Extraction of plant material – Isolation of natural products using separation techniques – Structural characterization through combined spectroscopic methods.

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