Andrea Pintore

Dr. Andrea Pintore

Università degli Studi di Salerno
orcid

Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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13 October 2022 in Orthopedic Reviews
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Journal Article
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EMEmanuela Marsillo
Emanuela Marsillo
APAndrea Pintore
Andrea Pintore
GAGiovanni Asparago
Giovanni Asparago
FOFrancesco Oliva
Francesco Oliva
NMNicola Maffulli
Nicola Maffulli
Introduction: Reverse oblique intertrochanteric fractures are classified by the Orthopaedic Trauma Association [OTA]/[AO] as 31A3, and account for up to one-third of all hip fractures, and 2–23% of all trochanteric fractures. The treatment of choice of those fractures is intramedullary nailing as it decreases soft tissue damage and permits early weight bearing. Material and methods: A retrospective comparative study was conducted on patients surgically treated for 31A3 fractures from October 2018 to January 2022 in a high-volume regional referral centre. All the patients had been treated with intramedullary nailing. Results: The selected group included 11 males (16%) and 59 females (84%), with a mean age of 83.6 years (range 61 to 96 years). A Trigen Intertan Nail was the most frequent choice of intramedullary nailing in 33 patients (47%), an Elos Long nail was chosen in 19 cases (27%), while a ZNN nail was used in 18 patients (26%). The mean time between admission and surgery was 2.5 days, with a mean Hb value of 10.5 g/dl reported preoperatively. Conclusion: Patients treated with an Intertan nail reported the lowest TAD, CALTAD, and TALCALTAD mean radiographic values, and the lowest rate of Hb loss and blood transfusions.

11 May 2023 in Journal of Orthopaedic Surgery and Research
Verified
Journal Article
Open access
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APAndrea Pintore
Andrea Pintore
DNDonato Notarfrancesco
Donato Notarfrancesco
AZArnaldo Zara
Arnaldo Zara
AOAntonio Oliviero
Antonio Oliviero
Filippo MiglioriniFilippo Migliorini
Filippo Migliorini
Nicola MaffulliNicola Maffulli
Nicola Maffulli
Background: We determined whether autologous mesenchymal stem cells (MSCs) injections provide clinical and functional improvements in knee osteoarthritis (KOA) patients, and whether the results differ between autologous bone marrow cells (BMAC) and adipose-derived stromal cells (ADSCs). Methods: Between January 2021 and April 2022, 51 patients undergoing intra-articular injection of BMAC and 51 patients undergoing intra-articular injection of ADSCs were prospectively recruited. The Kellgren and Lawrence (K–L) classification was used to grade the severity of osteoarthritis. Knee Injury and Osteoarthritis Outcome Score (KOOS), Oxford Knee Score (OKS), and visual analog scale (VAS) were collected for all 102 patients in the previous week before the procedures, and at the one and 6 months from injection. Results: Knee KOOS scores, knee OKS scores, and VAS pain scores changed in similar ways in the two treatment groups. Both treatment groups demonstrated significant improvement pre-procedure to post-procedure in knee KOOS scores (p < 0.0001), knee OKS scores (p < 0.0001), and VAS pain scores (p < 0.0001). Patients with K–L grade 2 showed better functional and clinical outcomes than patients with K–L grades 3 and 4 (p < 0.0001). Conclusion: Both intra-articular BMAC and ADSC injections significantly improved pain and functional outcomes at 6-month follow-up in patients with KOA. The difference between BMAC and ADCSs groups as tissue sources of MSCs was not statistically significant in terms of clinical and functional outcomes.

22 April 2022 in British Medical Bulletin
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Journal Article
Open access
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Filippo MiglioriniFilippo Migliorini
Filippo Migliorini
APAndrea Pintore
Andrea Pintore
GVGianluca Vecchio
Gianluca Vecchio
FOFrancesco Oliva
Francesco Oliva
FHFrank Hildebrand
Frank Hildebrand
Nicola MaffulliNicola Maffulli
Nicola Maffulli
Introduction: Several autografts are available to reconstruct the posterior cruciate ligament (PCL). Source of data: Current scientific literature published in PubMed, Google scholar, Embase and Scopus. Areas of agreement: Hamstring, bone-patellar tendon-bone (BPTB), quadriceps and peroneus longus (PLT) are the most common tendon autografts used for primary isolated PCL reconstruction. Areas of controversy: The optimal tendon source for PCL reconstruction remains nevertheless debated. Identifying the most suitable tendon autograft could assist the surgeon during primary PCL reconstruction. Growing points: The present study compared the outcome of PCL reconstruction using hamstring, BPTB, quadriceps and PLT autografts. The focus was on patient-reported outcome measures (PROMs), joint laxity, range of motion and complications. Areas timely for developing research: All autografts are viable options for PCL reconstruction, with BTB and hamstring autografts demonstrating superior PROMs. However, further clinical investigations are required to determine the ideal autograft construct.

4 May 2022 in British Medical Bulletin
Verified
Journal Article
Open access
PDF file
Filippo MiglioriniFilippo Migliorini
Filippo Migliorini
APAndrea Pintore
Andrea Pintore
GVGianluca Vecchio
Gianluca Vecchio
FOFrancesco Oliva
Francesco Oliva
FHFrank Hildebrand
Frank Hildebrand
Nicola MaffulliNicola Maffulli
Nicola Maffulli
Introduction: Several strategies are available for posterior cruciate ligament (PCL) reconstruction. Source of data: Recently published literature in PubMed, Google Scholar and Embase databases. Areas of agreement: The Ligament Advanced Reinforcement System (LARS) is a scaffold type artificial ligament, which has been widely used for ligament reconstruction of the knee. Areas of controversy: Current evidence on the reliability and feasibility of LARS for primary isolated PCL reconstruction is limited. Growing points: The primary outcome of interest of the present work was to investigate the outcomes of PCL reconstruction using the LARS. The secondary outcome of interest was to compare the LARS versus four-strand hamstring tendon (4SHT) autograft for PCL reconstruction. Areas timely for developing research: LARS for primary isolated PCL reconstruction seems to be effective and safe, with results comparable to the 4SHT autograft.

28 October 2021 in Applied Sciences
Verified
Journal Article
Open access
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Filippo MiglioriniFilippo Migliorini
Filippo Migliorini
GVGianluca Vecchio
Gianluca Vecchio
ABAlice Baroncini
Alice Baroncini
APAndrea Pintore
Andrea Pintore
Francesco OlivaFrancesco Oliva
Francesco Oliva
Nicola MaffulliNicola Maffulli
Nicola Maffulli
Purpose: Both anatomic total shoulder arthroplasty (TSA) and shoulder hemiarthroplasty (SHA) are used for the management of end-stage glenohumeral osteoarthritis (GHOA). The present study compared TSA and SHA in terms of clinical outcome and complication rate. Methods: This meta-analysis followed the PRISMA guidelines. In October 2021, the following databases were accessed: Web of Science, Google Scholar, Pubmed, Scopus. All clinical trials comparing anatomical TSA versus SHA for GHOA were considered. Results: Data from 11,027 procedures were retrieved. The mean length of the follow-up was 81.8 (16 to 223.20) months. The mean age of the patients was 61.4 ± 8.6 years, and 56.0% (5731 of 10,228 patients) were women. At last follow-up, the age-adjusted constant score was greater following TSA (p < 0.0001), as were active elevation (p < 0.0001), flexion (p < 0.0001), abduction (p < 0.0001), and American Shoulder and Elbow Surgeons Shoulder Score (p < 0.0001). Postoperative pain (p < 0.0001) and revision rate (p = 0.02) were lower in the TSA group. Conclusions: Anatomic TSA performed better than SHA in patients with GHOA.

4 July 2024 in Archives of orthopaedic and trauma surgery
Verified
Journal Article
Open access
PDF file
APAndrea Pintore
Andrea Pintore
AAAlberto Astone
Alberto Astone
GVGianluca Vecchio
Gianluca Vecchio
GAGiovanni Asparago
Giovanni Asparago
GCGiampiero Calabrò
Giampiero Calabrò
Nicola MaffulliNicola Maffulli
Nicola Maffulli
Introduction: Metacarpal fractures account for 25%-50% of all hand fractures and may negatively impact hand function and ability to work. Percutaneous transverse pinning of non-articular metacarpal fractures allows mobilisation immediately after the procedure. Methods: Between March 2017 and February 2022, 56 patients undergoing percutaneous transverse pinning for unstable metacarpal fractures were prospectively recruited. We investigated surgical outcomes in terms of Patient-rated Wrist/Hand Evaluation (PRWHE) and pre-and post-operative radiographic evaluation. The Student t-test was used to compare the means of PRWHE values after surgery. Statistical significance was set at p < 0.05. Results: The mean age was 40.21 ± 17.9 years (range of 16 to 86 years). The average operating time was 27.96 min. The mean follow-up period was 14.3 ± 6.4 months (from 2 to 41 months). The mean PRWHE score was 6.5 ± 1.8. None of the patients had clinically observable rotational deformities, and the functional outcomes were satisfactory. Conclusion: Percutaneous transverse pinning for non-articular metacarpal fractures restores excellent function, and imaging results are satisfactory. Further high-quality clinical trials are required to validate these results on a larger scale. Level of evidence: II, prospective cohort study.