Aleksandra Czerw

Prof. Aleksandra Czerw

orcid

Research Focus & Metrics

Academic Career Length

15Years (2012-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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15 July 2023 in Cancers
Verified
Journal Article
Open access
PDF file
OPOlga Partyka
Olga Partyka
MPMonika Pajewska
Monika Pajewska
DKDaria Kwaśniewska
Daria Kwaśniewska
ACAleksandra Czerw
Aleksandra Czerw
ADAndrzej Deptała
Andrzej Deptała
Remigiusz KozlowskiRemigiusz Kozlowski
Remigiusz Kozlowski
Pancreatic cancer is the seventh most common cause of death in the group of oncological diseases. Due to the asymptomatic course, early diagnosis is difficult. Currently, early detection methods are only used in high-risk groups. A literature review based on the available results of observational studies on patients with pancreatic cancer and people from high-risk groups was used to summarize the knowledge on risk factors. The GLOBOCAN 2020 data were used to assess the epidemiological situation in Europe. A summary of screening recommendations was prepared based on the available documents from medical organizations and associations. Pancreatic cancer risk factors are divided into two main groups: non-modifiable factors, e.g., hereditary factors and age, which increase the risk of developing this disease, and modifiable factors—BMI, smoking, and alcohol consumption. Hereditary factors account for 10% of pancreatic cancer cases. The highly specialized methods of early detection, (MRI, CT, or EUS) are used for screening high-risk populations. Of all the imaging methods, EUS is considered the most sensitive for pancreatic cancer and allows an accurate assessment of the size of even small lesions (<30 mm) and the extent of tumour infiltration into blood vessels. The available studies vary on the level of sensitivity and specificity of these methods for the diagnosis of pancreatic cancer. EUS, MRI, and CT are also expensive procedures and in some patients can be invasive, which is one of the arguments against the introduction of population screening programs based on imaging methods. Therefore, it is important to look for viable solutions that would improve early detection. This is important from the point of view of healthcare systems in Europe, where almost 29% of all global pancreatic cancer cases are reported.

ALAgata Lewandowska
Agata Lewandowska
Urszula ReligioniUrszula Religioni
Urszula Religioni
ACAleksandra Czerw
Aleksandra Czerw
ADAndrzej Deptała
Andrzej Deptała
BKBeata Karakiewicz
Beata Karakiewicz
Piotr MerksPiotr Merks
Piotr Merks
Colorectal cancer is one of the most common cancers in Europe and the world. Cancer treatments have side effects and cause significant deterioration of the patient’s nutritional status. Patient malnutrition may worsen the health condition and prevent the deliberate effects of the therapy. The aim of this review was to describe the available data about clinical nutrition in colorectal cancer patients. A large proportion of colorectal cancer patients suffer from malnutrition, which negatively affects the survival prognosis, quality of life, and oncological therapy. Therefore, monitoring nutritional status during the treatment is essential and can be used to arrange proper nutritional therapy to enhance patient responses, prevent side effects, and shorten recovery time. The principles of nutrition during anticancer therapy should mainly consider light and low-fat foods, the exclusion of lactose and gluten-containing foods in certain cases, or the introduction of special dietary products such as oral nutrition supplements and it should be tailored to patients’ individual needs.

MMMikos Marcin
Mikos Marcin
TBTomasz Banas
Tomasz Banas
ACAleksandra Czerw
Aleksandra Czerw
BBBartlomiej Banas
Bartlomiej Banas
ŁSŁukasz Strzępek
Łukasz Strzępek
MCMateusz Curyło
Mateusz Curyło
Background: Inpatient falls are common hospital adverse events. We aimed to determine inpatient fall rates in an urban public hospital and analyzed their characteristics across clinical departments. Methods: The study was conducted in a 350-bed urban, multi-specialty public hospital in the 2013–2019 period. Patient data were retrieved from the hospital’s standardized falls reporting system. Descriptive statistics and statistical tests: chi2 and ANOVA tests with multiple comparison tests (post-hoc analysis) were used. For fall incidence estimation a joint-point regression was applied. p-value of 0.05 was considered as statistically significant for all the calculations. Results: The highest prevalence of falls was reported in the rehabilitation and internal medicine wards (1.915% and 1.181%, respectively), the lowest in the orthopedic (0.145%) and rheumatology wards (0.213%) (p < 0.001). The vast majority of falls took place in the late evening and during the night (56.711%) and were classified as bed falls (55.858%). The crude incidence rate (cIR) of falls was 6.484 per one thousand hospitalizations. In the 2013–2017 period, an increase in total cIR was observed, reaching the peak value in 2016; it was followed by a slight decline from 2017 to 2019, however, differences in changes were observed between the wards. Conclusion: Fall rates and trends as well as circumstances of inpatient falls varied significantly among clinical departments, probably due to differences in patient characteristics.

2 June 2015 in Breast Cancer
Verified
Journal Article
Open access
PDF file
ACAleksandra Czerw
Aleksandra Czerw
URUrszula Religioni
Urszula Religioni
ADAndrzej Deptała
Andrzej Deptała
Introduction Breast cancer is the most common malignant neoplasm in women. Over the past 40 years, the number of patients diagnosed with breast cancer quadrupled. Breast cancer is one of the most frequent causes of death in women aged 65 and more in Poland. Purpose The purpose of the study was to evaluate coping strategies, pain management, disease acceptance and adjustment to cancer in patients diagnosed with breast cancer and to assess the effect of socioeconomic variables on the above mentioned issues. Methods The study included 193 patients diagnosed with breast cancer during outpatient chemotherapy (classical chemotherapy, hormone therapy, molecularly targeted therapies) at the Center of Oncology, Maria Skłodowska-Curie Institute in Warsaw. We applied the Paper and Pencil Interview (PAPI) technique. The questionnaire interview consisted of demographic questions (socioeconomic variables) and the following four psychometric tests: BPCQ (Beliefs about Pain Control Questionnaire), measuring the influence of factors affecting pain management in patients, CSQ (Coping Strategies Questionnaire), designed to evaluate pain coping strategies, AIS (Acceptance of Illness Scale) questionnaire, measuring disease acceptance, and the mini-MAC (Mental Adjustment to Cancer) scale. Results The results of BPCQ show that breast cancer patients mostly believe that doctors control pain; the mean result for the group was 17.09 and test values were differentiated by education and professional status. The top average score in the pain coping strategies questionnaire was recorded in the positive coping self-statement subscale (mean score = 21.81), whereas the lowest, in the catastrophizing subscale (mean score = 10.60). Here, education and income proved most significant in accounting for the differences recorded. The mean score on the AIS was 28.45, and the key factor differentiating the results was income. As far as the mini-MAC is concerned, we reported the highest score in the fighting spirit subscale (23.43). The average results in the scale were slightly differentiated by socioeconomic variables. Conclusions Breast cancer patients mostly believe that those who control pain are doctors. Amongst the strategies of coping with pain, the top average score was recorded in the positive coping self-statement subscale. We found out that the level of disease acceptance depends on respondent’s income. The higher the income, the greater the acceptance of illness.

Elżbieta CiporaElżbieta Cipora
Elżbieta Cipora
ACAleksandra Czerw
Aleksandra Czerw
OPOlga Partyka
Olga Partyka
MPMonika Pajewska
Monika Pajewska
ABAnna Badowska-Kozakiewicz
Anna Badowska-Kozakiewicz
ADAndrzej Deptała
Andrzej Deptała
Pancreatic cancer is the malignant disease with the highest mortality rate, and it ranks third in the world after lung and colon cancer. Identified factors that increase the risk of developing pancreatic cancer include chronic pancreatitis, radiation therapy to the pancreatic area due to another cancer, diabetes mellitus, obesity, smoking, and age. The objective of this study was to present the current state of knowledge on the quality of life of patients diagnosed with pancreatic cancer, factors that determine QoL, and ways of coping with the disease. The low curability and low survival rates of pancreatic cancer significantly affect the quality of life of patients, often in the form of significant deterioration, especially in terms of mental changes, cognitive functions, and coping with the disease. Cognitive decline with comorbid depression is also typical for patients with this type of cancer. Research has shown that the health-related quality of life of patients with pancreatic cancer is low, so further research is needed to improve the situation in this area.

23 January 2018 in Polish Heart Journal
Verified
Journal Article
Closed access
PDF file
AKAlicja Kucharska
Alicja Kucharska
Danuta GajewskaDanuta Gajewska
Danuta Gajewska
MKMirosław Kiedrowski
Mirosław Kiedrowski
BSBEATA SIŃSKA
BEATA SIŃSKA
GJGrzegorz Piotr Juszczyk
Grzegorz Piotr Juszczyk
JNJoanna Niegowska
Joanna Niegowska
Background and aim: The aim of the study was to assess the impact of individualized nutritional intervention according to DASH principles (Dietary Approaches to Stop Hypertension) on the nutritional status, blood pressure, and selected biochemical parameters of obese /overweight patients with primary arterial hypertension. Methods: 131 participants were randomized to the DASH intervention group (DIG; n=69, 33 males) or the control group (CG; n=62, 32 males). A three month nutritional intervention was carried out in the DIG, while the control group received only standard recommendations. Body weight, height, waist and hip circumference, body composition, blood pressure, serum glucose, insulin and leptin concentrations were measured at the baseline and after the intervention. Results: 64 (92,8%) participants in the intervention and 62 (100%) in the control group completed the study. A significant decrease in body mass, systolic and diastolic blood pressure, body fat content, fasting glucose, insulin and leptin concentrations along with respective anthropometric and biochemical indices was observed in the DIG group (P < 0.05). Conclusions: The DASH dietary intervention provides significant benefits to overweight/obese patients with primary hypertension. Background and aim: The aim of the study was to assess the impact of individualized nutritional intervention according to DASH principles (Dietary Approaches to Stop Hypertension) on the nutritional status, blood pressure, and selected biochemical parameters of obese /overweight patients with primary arterial hypertension. Methods: 131 participants were randomized to the DASH intervention group (DIG; n=69, 33 males) or the control group (CG; n=62, 32 males). A three month nutritional intervention was carried out in the DIG, while the control group received only standard recommendations. Body weight, height, waist and hip circumference, body composition, blood pressure, serum glucose, insulin and leptin concentrations were measured at the baseline and after the intervention. Results: 64 (92,8%) participants in the intervention and 62 (100%) in the control group completed the study. A significant decrease in body mass, systolic and diastolic blood pressure, body fat content, fasting glucose, insulin and leptin concentrations along with respective anthropometric and biochemical indices was observed in the DIG group (P < 0.05). Conclusions: The DASH dietary intervention provides significant benefits to overweight/obese patients with primary hypertension.