Alzheimer's disease is a neurodegenerative condition that gradually impairs cognitive abilities. Recently, various neuroimaging modalities and machine learning methods have surfaced to diagnose Alzheimer's disease. Resting-state fMRI is a neuroimaging modality that has been widely utilized to study brain activity related to neurodegenerative diseases. In literature, the previous studies are limited to the binary classification of Alzheimer's disease and Mild Cognitive Impairment. The application of computer-aided diagnosis for the numerous advancing phases of Alzheimer's disease, on the other hand, remains understudied. This research analyzes and presents methods for multi-label classification of six Alzheimer's stages using rs-fMRI and deep learning. The proposed model solves the multi-class classification problem by extracting the brain's functional connectivity networks from rs-fMRI data and employing two deep learning approaches, Stacked Sparse Autoencoder and Brain Connectivity Graph Convolutional Network. The suggested models' results were assessed using the k-fold cross-validation approach, and an average accuracy of 77.13% and 84.03% was reached for multi-label classification using Stacked Sparse Autoencoders and Brain Connectivity Based Convolutional Network, respectively. An analysis of brain regions was also performed by using the network's learned weights, leading to the conclusion that the precentral gyrus, frontal gyrus, lingual gyrus, and supplementary motor area are the significant brain regions of interest.
Explainable Artificial Intelligence is a key component of artificially intelligent systems that aim to explain the classification results. The classification results explanation is essential for automatic disease diagnosis in healthcare. The human respiration system is badly affected by different chest pulmonary diseases. Automatic classification and explanation can be used to detect these lung diseases. In this paper, we introduced a CNN-based transfer learning-based approach for automatically explaining pulmonary diseases, i.e., edema, tuberculosis, nodules, and pneumonia from chest radiographs. Among these pulmonary diseases, pneumonia, which COVID-19 causes, is deadly; therefore, radiographs of COVID-19 are used for the explanation task. We used the ResNet50 neural network and trained the network on extensive training with the COVID-CT dataset and the COVIDNet dataset. The interpretable model LIME is used for the explanation of classification results. Lime highlights the input image’s important features for generating the classification result. We evaluated the explanation using radiologists’ highlighted images and identified that our model highlights and explains the same regions. We achieved improved classification results with our fine-tuned model with an accuracy of 93% and 97%, respectively. The analysis of our results indicates that this research not only improves the classification results but also provides an explanation of pulmonary diseases with advanced deep-learning methods. This research would assist radiologists with automatic disease detection and explanations, which are used to make clinical decisions and assist in diagnosing and treating pulmonary diseases in the early stage.
As wheat is one of the major crops worldwide, therefore, accurate disease detection in wheat plants is critical for mitigating effects and halting disease spread. Nowadays, the detection of diseases through images using machine learning and deep learning has achieved state-of-art results. Yet these models suffer from two shortcomings, one is the data-hungry models of deep learning, and the second is the adaption of new classes with previous ones, i.e., if a new disease arrived, one must retrain the entire model with a new dataset which has led to the origination of few-shot learning that solves both problems. A wheat disease classification network is proposed based on a few-shot learning method for the classification of 18 wheat diseases using EfficientNet as a backbone. Also, the attention mechanism is incorporated to facilitate efficient feature selection. Our proposed network has achieved 93.19% accuracy on the 40 images of 18 disease classes manually collected from the internet while that of our backbone network EfficientNet has gained an accuracy of about 98.5% accuracy on CGIAR Dataset. The evaluation demonstrates that despite the presence of only a few images in both the training and query sets, the proposed model has achieved superior performance in terms of accuracy and computation cost. Furthermore, the evaluation also highlights the effectiveness of our model in terms of data and computation cost. The proposed method can be used for disease detection in wheat crops requiring less amount of data.
12 January 2021 in Computational Intelligence and Neuroscience
The novel coronavirus, SARS‐CoV‐2, can be deadly to people, causing COVID‐19. The ease of its propagation, coupled with its high capacity for illness and death in infected individuals, makes it a hazard to the community. Chest X‐rays are one of the most common but most difficult to interpret radiographic examination for early diagnosis of coronavirus‐related infections. They carry a considerable amount of anatomical and physiological information, but it is sometimes difficult even for the expert radiologist to derive the related information they contain. Automatic classification using deep learning models can help in better assessing these infections swiftly. Deep CNN models, namely, MobileNet, ResNet50, and InceptionV3, were applied with different variations, including training the model from the start, fine‐tuning along with adjusting learned weights of all layers, and fine‐tuning with learned weights along with augmentation. Fine‐tuning with augmentation produced the best results in pretrained models. Out of these, two best‐performing models (MobileNet and InceptionV3) selected for ensemble learning produced accuracy and FScore of 95.18% and 90.34%, and 95.75% and 91.47%, respectively. The proposed hybrid ensemble model generated with the merger of these deep models produced a classification accuracy and FScore of 96.49% and 92.97%. For test dataset, which was separately kept, the model generated accuracy and FScore of 94.19% and 88.64%. Automatic classification using deep ensemble learning can help radiologists in the correct identification of coronavirus‐related infections in chest X‐rays. Consequently, this swift and computer‐aided diagnosis can help in saving precious human lives and minimizing the social and economic impact on society.
In order to provide benchmark performance for Urdu text document classification, the contribution of this paper is manifold. First, it provides a publicly available benchmark dataset manually tagged against 6 classes. Second, it investigates the performance impact of traditional machine learning-based Urdu text document classification methodologies by embedding 10 filter-based feature selection algorithms which have been widely used for other languages. Third, for the very first time, it assesses the performance of various deep learning-based methodologies for Urdu text document classification. In this regard, for experimentation, we adapt 10 deep learning classification methodologies which have produced best performance figures for English text classification. Fourth, it also investigates the performance impact of transfer learning by utilizing Bidirectional Encoder Representations from Transformers approach for Urdu language. Fifth, it evaluates the integrity of a hybrid approach which combines traditional machine learning-based feature engineering and deep learning-based automated feature engineering. Experimental results show that feature selection approach named as normalized difference measure along with support vector machine outshines state-of-the-art performance on two closed source benchmark datasets CLE Urdu Digest 1000k, and CLE Urdu Digest 1Million with a significant margin of 32% and 13%, respectively. Across all three datasets, normalized difference measure outperforms other filter-based feature selection algorithms as it significantly uplifts the performance of all adopted machine learning, deep learning, and hybrid approaches. The source code and presented dataset are available at Github repository https://github.com/minixain/Urdu-Text-Classification.