Carla Borrell García

Dr. Carla Borrell García

orcid

Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 January 2021 in International Journal of Immunopathology and Pharmacology
Verified
Journal Article
Open access
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CGCarla Borrell García
Carla Borrell García
MLMarta Ribelles Llop
Marta Ribelles Llop
MEMaria Ángeles García Esparza
Maria Ángeles García Esparza
AFAntonio Juan Flichy-Fernández
Antonio Juan Flichy-Fernández
LMLaura Marqués Martínez
Laura Marqués Martínez
RFRegina Izquierdo Fort
Regina Izquierdo Fort
To assess the effects of a probiotic upon oral health indices in adolescents and to establish relationships between these indices and dietary habits and oral hygiene. Twenty-seven adolescents between 12 and 18 years of age were randomized into two groups. The study group received tablets containing Lactobacillus reuteri DSM 17938/ATCC 5289 for 28 days, while the control group received tablets without any bacteria. Streptococcus mutans, Lactobacillus sp., and salivary pH were assessed at baseline and at 7, 14, 21, 28, and 45 days. The plaque, gingivitis, and bleeding indices were recorded at baseline and at 14, 28, and 45 days. Dietary and oral hygiene habits were also evaluated by means of a questionnaire. A less marked rise in S. mutans was recorded in the study group. Improvements were observed in terms of plaque, gingivitis, and bleeding, though statistical significance was not reached. Oral pH increased in the study group, though not to a significant degree. Poorer eating habits were significantly correlated to increased plaque. The study parameters decreased with the two strains of L. reuteri DSM 17938 and ATCC PTA 5289, though the results failed to reach statistical.

1 September 2022 in Nutrients
Verified
Journal Article
Open access
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LMLaura Marqués MArtínez
Laura Marqués MArtínez
MPMarcelino Pérez-Bermejo
Marcelino Pérez-Bermejo
ALAna Rosa Lairón-Peris
Ana Rosa Lairón-Peris
CBClara Guinot Barona
Clara Guinot Barona
CGCarla Borrell García
Carla Borrell García
EMEsther Garcia Miralles
Esther Garcia Miralles
Children who show better eating practices are less likely to suffer from severe caries than those who eat a diet rich in sugars. In the present study, we aimed to establish the relationship between the severity of dental caries and adherence to the Mediterranean diet. A cross-sectional study was carried out in which 263 children aged 2 to 14 years old were examined intraorally to analyze the presence and severity of caries. Children’s parents/caregivers completed the KIDMED questionnaire to determine their degree of adherence to the Mediterranean diet. The results showed that the prevalence of caries is greater than 80% in children with medium or low adherence to the Mediterranean diet, and remains significant at 67% in the high adherence group (p = 0.010). A statistically significant negative correlation of weak magnitude (r = −0.29; p < 0.001) was found between adherence and the number of carious teeth. Caries severity in the first molars is also influenced by adherence to the diet in a statistically significant way. In conclusion, there is an association between adherence to the Mediterranean diet and the prevalence, extension, and severity of caries in the pediatric population.

5 February 2024 in Children
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Journal Article
Open access
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PGPaula Boo Gordillo
Paula Boo Gordillo
LMLaura Marqués MArtínez
Laura Marqués MArtínez
CGCarla Borrell García
Carla Borrell García
EMEsther Garcia Miralles
Esther Garcia Miralles
Craniofacial growth and development have been shown to be influenced by various environmental factors that impact child development. This study aims to analyze the different patterns of feeding during early childhood, starting from birth, and assess the variability of nutrition during the first stage of childhood, along with the habits developed, to study their impact on jaw development. The study was conducted on a sample of twenty-five patients aged 3 to 5, following approval from the ethics committee of the Catholic University of Valencia. Informed consent was obtained from the fathers, mothers, and/or legal guardians, who were administered surveys on habits and diet. Cephalometric measurements within the parameters of ideal occlusion were subsequently taken. While previous studies examined this subject, the findings are challenging to evaluate. However, this study identified significant associations (p = 0.001) between clinical measurements and children’s eating habits. The growth and development of the craniofacial cavity are influenced by multiple factors, including a child’s diet and habits. Nonetheless, further research is required to determine whether diet can be considered a determining factor in proper jaw growth.

13 October 2025 in Children
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Journal Article
Open access
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LMLaura Marqués MArtínez
Laura Marqués MArtínez
JAJorge Andrés
Jorge Andrés
EMEsther Garcia Miralles
Esther Garcia Miralles
CGCarla Borrell García
Carla Borrell García
JUAN IGNACIO AURA-TORMOSJUAN IGNACIO AURA-TORMOS
JUAN IGNACIO AURA-TORMOS
CBClara Guinot Barona
Clara Guinot Barona
Background: Dental anxiety is a common challenge in paediatric dentistry, often leading to avoidance of treatment and compromised oral health. Non-pharmacological interventions such as music therapy have gained increasing attention as safe and cost-effective alternatives to pharmacological approaches. Although several clinical studies have examined the impact of music on children’s dental anxiety, the evidence has not yet been systematically summarised with quantitative synthesis. Objective: This systematic review and meta-analysis aimed to evaluate the effectiveness of music therapy in reducing dental anxiety and fear among paediatric patients. Methods: A comprehensive literature search was conducted in PubMed, Scopus, Web of Science, and Cochrane Library from inception to August 2025. Randomised controlled trials (RCTs) evaluating music therapy for dental anxiety in children were included. Primary outcomes were self-reported dental anxiety/fear scales and physiological measures (heart rate, blood pressure, oxygen saturation). Risk of bias was assessed using the revised Cochrane risk of bias tool (RoB 2, version 2019; Cochrane Collaboration, London, UK) Meta-analyses were performed using a random-effects model with Review Manager (RevMan, version 5.4; Cochrane Collaboration, London, UK). Results: Seven randomized controlled trials (RCTs) involving 476 children aged 4–14 years were included. Music therapy significantly reduced self-re-ported dental anxiety compared with control groups (SMD = −0.48, 95% CI: −0.72 to −0.25, p < 0.001). Heart rate was also significantly reduced (SMD = −0.42, 95% CI: −0.68 to −0.16, p = 0.002), whereas changes in blood pressure and oxygen saturation were not statistically significant. The overall risk of bias was moderate, with most concerns related to blinding. Conclusions: Music therapy is an effective non-pharmacological intervention to reduce dental anxiety in children, particularly improving subjective anxiety and physiological arousal as measured by heart rate. Its integration into paediatric dental practice may enhance cooperation and treatment outcomes, offering a safe, inexpensive, and child-friendly approach.

1 January 2021 in Nutrición Hospitalaria
Verified
Journal Article
Open access
CGCarla Borrell García
Carla Borrell García
EMEsther Garcia Miralles
Esther Garcia Miralles
LMLaura Marqués MArtínez
Laura Marqués MArtínez
Revista oficial de la Sociedad Española de Nutrición Parenteral y de la Sociedad Española de Nutrición. Está dedicada al estudio y divulgación de temas relacionados con la nutrición.

26 November 2025 in Journal of Clinical Medicine
Verified
Journal Article
Open access
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EMEsther Garcia Miralles
Esther Garcia Miralles
LMLaura Marqués MArtínez
Laura Marqués MArtínez
CGCarla Borrell García
Carla Borrell García
PGPaula Boo Gordillo
Paula Boo Gordillo
JUAN IGNACIO AURA-TORMOSJUAN IGNACIO AURA-TORMOS
JUAN IGNACIO AURA-TORMOS
CBClara Guinot Barona
Clara Guinot Barona
Background: Tooth autotransplantation represents a biologically favourable treatment option for replacing missing or non-restorable teeth in paediatric patients. However, its long-term prognosis and variability in reported success rates warrant a high-quality synthesis of the available evidence. Methods: A systematic review was conducted following the PRISMA 2020 guidelines. A comprehensive search of PubMed, Scopus, Web of Science, and Cochrane CENTRAL was performed up to May 2024 for clinical studies on autotransplantation of immature permanent teeth in patients under 18 years. Study selection, data extraction, and risk-of-bias assessment (using ROBINS-I and JBI tools) were performed independently by two reviewers. Aggregated success and survival proportions with 95% confidence intervals were calculated through descriptive quantitative synthesis. Results: Three retrospective studies, comprising 404 transplanted teeth, were included in the analysis. The aggregated success proportion was 85.4% (95% CI: 74.4–92.1%), and the aggregated survival proportion was 94.2% (95% CI: 85.0–97.9%), with a mean follow-up ranging from 12 to 168 months. A key finding was that all included studies consistently reported the use of immature donor teeth (1/2–3/4 root formation) and short-term flexible splinting, which appears to be a critical factor for these successful outcomes. Conclusions: Autotransplantation of developing teeth in paediatric patients demonstrates high survival (≈94%) and favourable success (≈85%), with minimal inter-study variability. When performed with immature donor roots and short-term flexible splinting, the procedure provides a predictable biological alternative to prosthetic or implant rehabilitation in growing individuals. However, the limited number of eligible studies highlights the need for future multicentre prospective research to standardise protocols and confirm long-term outcomes in paediatric populations.