The Neoproterozoic to Paleozoic Proto-Tethys Ocean has preserved critical records of Earth’s evolutionary history. The Lower Cambrian detrital strata along the northern margin of the Yangtze Block provide valuable information for gaining insight into the evolution of the Proto-Tethys Ocean, which is important in understanding the collision between the Yangtze Block and the Gondwana assembly. Here, we present comprehensive U-Pb ages and trace elements of zircons from Lower Cambrian detrital strata in the Yangtze Block. Our results revealed prominent age peaks at 600–500 Ma and 1100–800 Ma for detrital zircons in the Cambrian strata. The trace element characteristics of the detrital zircon indicate that the source rocks were mainly intermediate-felsic magmatic suites with minor input from mafic sources. These results suggest that the detrital materials were not only supplied from the interior of the Yangtze Block but also from magmatic sources in the internal orogenic belt of Gondwana. Furthermore, the kernel density estimate plots of detrital zircon U-Pb ages indicate a stable source-sink system in the Yangtze Block during the Early Cambrian. However, our data indicate that the crustal thickness of the Yangtze Block increased significantly since ca. 526 Ma, and the cumulative characteristics of the detrital zircons indicate that the rocks were deposited in a compressional tectonic environment after ca. 526 Ma, in contrast to those during the late Neoproterozoic, which were generally deposited in an extensional tectonic environment. This transition indicates that the initial collision between the Yangtze Block and the Gondwana supercontinent might have occurred at ca. 526 Ma, marking the rapid aggregation of the northern domain of the Gondwana assembly and potentially serving as an important indicator of the closure of the Yangtze-associated Proto-Tethys Ocean. Our findings provide key insights into late Neoproterozoic–early Paleozoic ocean-land evolution.

The Upper Ordovician–Lower Silurian mudstones (including the Wufeng, Guanyinqiao and Longmaxi Formations) in the Sichuan Basin are some of the most important shale gas plays in China. In order to enhance our understanding of the process of formation of organic carbon up to 10%, optical, microscopy and geochemical methods have been used to investigate the petrographic and geochemical characteristics of the formation. Firstly, three mudstone lithofacies were identified based on a wide variety of mudstone laminations. These are: (a) indistinctly laminated mudstone; (b) parallel-laminated mudstone; and (c) nonparallel-laminated mudstone. Then, combining with the evidence from depocenter migration, Th/U ratios and total organic carbon, the abundant organo-minerallic fabrics suggest that organic carbon was preferentially deposited and preserved in anoxic, low energy and stagnant water conditions during deposition of the Wufeng and Longmaxi Formations. On the contrary, the Guanyinqiao Formation with poor organic carbon was deposited in oxic and high-energy water conditions.

The co-occurrence of hepatic cystic echinococcosis (CE) and alveolar echinococcosis (AE) is extremely rare. Here, we present the clinical manifestations and treatment outcomes of three cases with co-occurring CE and AE in the liver. Computed tomography (CT), magnetic resonance imaging and ^18FFluorodeoxyglucose Positron Emission Tomography-CT were used for preoperative diagnosis. Specimens were taken intraoperatively and sent for pathological studies to confirm the coexistence of CE and AE by laminated membrane, daughter cysts or germinal layer and infiltration structure. Albendazole was prescribed after operation for 12 months. All patients were completely recovered and showed no recurrence at last follow-up. Therefore, surgical intervention and postoperative application of albendazole are recommended for patients with concurrence of hepatic AE and CE.

The increasing proportion of unconventional worldwide energy demands have consistently promoted the necessity for exploring a precise, high-resolution, objective, and quantitative stratigraphic division method for macroscopically homogeneous mudstone successions. The chemostratigraphy can resolve this problem well, although it has been applied successfully in North America, but not systematically studied in China for shale gas exploration and development. This work has conducted a chemostratigraphic analysis of Wufeng and Longmaxi Formation on the Changning section of Sichuan Province, southwestern China, to testify its applicability for shale gas exploration in China. Principal component analysis (PCA) was first employed to reduce the dimensionality of datasets. Three chemofacies, including detrital (K, Ti, Fe, Al, Na, Mg, Cr, Zr, Rb), authigenic (Ca, Sr, Mn, Si, S, Ba), and redox-organic (P, V, Ni, Zn, Cu, TOC), were found. Subsequently, constrained clustering analysis was utilized for the zonation of each chemofacies into chemozones. Consequently, the whole Changning section was divided into twelve chemozones (CZ I–CZ Ⅻ). The geochemical interpretation for these chemozones can be resolved from the regional changes in paleogeography and paleoceanography during the Late Ordovician to Early Silurian period. Thus, a three-stage geochemical evolution along the Changning section can be classified: (1) the siliceous and anoxic deposits of Wufeng Formation (CZ I–CZ III) with high TOC contents; (2) the siliceous and anoxic sedimentary rocks of bottom Longmaxi Formation with still higher TOC (CZ Ⅳ); (3) the calcarous-detrital and oxic sediments for the rest of Longmaxi Formation (CZ Ⅴ–CZ Ⅻ). In considering their high content of TOC and abundant brittle siliceous minerals, the CZ (I–Ⅳ, 0 m–33.6 m) are thought to be the most preferable sweet spot for shale gas exploration.