Meta-learning empowers learning systems with the ability to acquire knowledge from multiple tasks, enabling faster adaptation and generalization to new tasks. This review provides a comprehensive technical overview of meta-learning, emphasizing its importance in real-world applications where data may be scarce or expensive to obtain. The paper covers the state-of-the-art meta-learning approaches and explores the relationship between meta-learning and multi-task learning, transfer learning, domain adaptation and generalization, selfsupervised learning, personalized federated learning, and continual learning. By highlighting the synergies between these topics and the field of meta-learning, the paper demonstrates how advancements in one area can benefit the field as a whole, while avoiding unnecessary duplication of efforts. Additionally, the paper delves into advanced meta-learning topics such as learning from complex multi-modal task distributions, unsupervised metalearning, learning to efficiently adapt to data distribution shifts, and continual meta-learning. Lastly, the paper highlights open problems and challenges for future research in the field. By synthesizing the latest research developments, this paper provides a thorough understanding of meta-learning and its potential impact on various machine learning applications. We believe that this technical overview will contribute to the advancement of meta-learning and its practical implications in addressing realworld problems.

Using a neural-network classifier we are able to separate gluon from quark jets originating from Monte Carlo–generated ${\mathit{e}}^{+}$ ${\mathit{e}}^{\mathrm{-}}$ events with 85%–90% accuracy.

Summary: A set of new algorithms and software tools for automatic protein identification using peptide mass fingerprinting is presented. The software is automatic, fast and modular to suit different laboratory needs, and it can be operated either via a Java user interface or called from within scripts. The software modules do peak extraction, peak filtering and protein database matching, and communicate via XML. Individual modules can therefore easily be replaced with other software if desired, and all intermediate results are available to the user. The algorithms are designed to operate without human intervention and contain several novel approaches. The performance and capabilities of the software is illustrated on spectra from different mass spectrometer manufacturers, and the factors influencing successful identification are discussed and quantified. Motivation: Protein identification with mass spectrometric methods is a key step in modern proteomics studies. Some tools are available today for doing different steps in the analysis. Only a few commercial systems integrate all the steps in the analysis, often for only one vendor's hardware, and the details of these systems are not public. Results: A complete system for doing protein identification with peptide mass fingerprints is presented, including everything from peak picking to matching the database protein. The details of the different algorithms are disclosed so that academic researchers can have full control of their tools. Availability: The described software tools are available from the Halmstad University website www.hh.se/staff/bioinf/ Supplementary information: Details of the algorithms are described in supporting information available from the Halmstad University website www.hh.se/staff/bioinf/