Korean Circulation Journal 대한심장학회지 순환기 Lee HJ, et al. Korean Circ J. 2022 Jun;52:e74. https://doi.org/10.4070/kcj.2022.0159

Kim J, et al. J Korean Med Sci. 2023 Dec;39(2):e18. https://doi.org/10.3346/jkms.2024.39.e18

Little is known about causality and the pathological mechanism underlying the association of serum lactate with myocardial injury in patients with acute myocardial infarction (AMI). We evaluated data from 360 AMI patients undergoing percutaneous coronary intervention (PCI) using cardiovascular magnetic resonance imaging (CMR). Of these, 119 patients had serum lactate levels > 2.5 mmol/L on admission (high serum lactate group), whereas 241 patients had serum lactate levels ≤ 2.5 mmol/L (low serum lactate group). We compared the myocardial infarct size assessed by CMR between the two groups and performed inverse probability of treatment weighting (IPTW). In CMR analysis, myocardial infarct size was significantly greater in the high serum lactate group than in the low serum lactate group (22.0 ± 11.4% in the high serum lactate group vs. 18.9 ± 10.5% in the low serum lactate group; p = 0.011). The result was consistent after IPTW adjustment (21.5 ± 11.1% vs. 19.2 ± 10.4%; p = 0.044). In multivariate analysis, high serum lactate was associated with larger myocardial infarct (odds ratio 1.59; 95% confidence interval 1.00–2.51; p = 0.048). High serum lactate could predict advanced myocardial injury in AMI patients undergoing PCI.

Lim J, et al. Korean Circ J. 2025 Mar;55:e72. https://doi.org/10.4070/kcj.2024.0443

Lee SY, et al. Yonsei Med J. 2023 Jul;64(7):413-422. https://doi.org/10.3349/ymj.2022.0649

김정주, et al. J Korean Soc Radiol. 2023 Nov;84:e117. https://doi.org/10.3348/jksr.2022.0170