Alfonso Reginelli

Dr. Alfonso Reginelli

Campania University "Luigi Vanvitelli"
+1
orcid

Research Focus & Metrics

Academic Career Length

21Years (2006-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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4 December 2021 in La radiologia medica
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Journal Article
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VNValerio Nardone
Valerio Nardone
ARAlfonso Reginelli
Alfonso Reginelli
RGRoberta Grassi
Roberta Grassi
LBLuca Boldrini
Luca Boldrini
GVGiovanna Vacca
Giovanna Vacca
SCSalvatore Cappabianca
Salvatore Cappabianca

4 May 2020 in La radiologia medica
Verified
Journal Article
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MBMaria Paola Belfiore
Maria Paola Belfiore
FUFabrizio Urraro
Fabrizio Urraro
RGRoberta Grassi
Roberta Grassi
GGGiuliana Giacobbe
Giuliana Giacobbe
GPGianluigi Patelli
Gianluigi Patelli
ARAlfonso Reginelli
Alfonso Reginelli
The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has already assumed pandemic proportions, affecting over 100 countries in few weeks. A global response is needed to prepare health systems worldwide. Covid-19 can be diagnosed both on chest X-ray and on computed tomography (CT). Asymptomatic patients may also have lung lesions on imaging. CT investigation in patients with suspicion Covid-19 pneumonia involves the use of the high-resolution technique (HRCT). Artificial intelligence (AI) software has been employed to facilitate CT diagnosis. AI software must be useful categorizing the disease into different severities, integrating the structured report, prepared according to subjective considerations, with quantitative, objective assessments of the extent of the lesions. In this communication, we present an example of a good tool for the radiologist (Thoracic VCAR software, GE Healthcare, Italy) in Covid-19 diagnosis (Pan et al. in Radiology, 2020. https://doi.org/10.1148/radiol.2020200370). Thoracic VCAR offers quantitative measurements of the lung involvement. Thoracic VCAR can generate a clear, fast and concise report that communicates vital medical information to referring physicians. In the post-processing phase, software, thanks to the help of a colorimetric map, recognizes the ground glass and differentiates it from consolidation and quantifies them as a percentage with respect to the healthy parenchyma. AI software therefore allows to accurately calculate the volume of each of these areas. Therefore, keeping in mind that CT has high diagnostic sensitivity in identifying lesions, but not specific for Covid-19 and similar to other infectious viral diseases, it is mandatory to have an AI software that expresses objective evaluations of the percentage of ventilated lung parenchyma compared to the affected one.

15 July 2013 in The Ultrasound Journal
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Journal Article
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APAntonio Pinto
Antonio Pinto
ARAlfonso Reginelli
Alfonso Reginelli
LCLucio Cagini
Lucio Cagini
FCFrancesco Coppolino
Francesco Coppolino
AIAntonio Amato Stabile Ianora
Antonio Amato Stabile Ianora
LRLuigia Romano
Luigia Romano
To evaluate the accuracy of ultrasonography in the diagnosis of acute calculous cholecystitis in comparison with other imaging modalities.

15 July 2013 in The Ultrasound Journal
Verified
Journal Article
Open access
FCFf Coppolino
Ff Coppolino
GGGianluca Gatta
Gianluca Gatta
Graziella Di GreziaGraziella Di Grezia
Graziella Di Grezia
ARAlfonso Reginelli
Alfonso Reginelli
FIFrancesca Iacobellis
Francesca Iacobellis
EGEa Genovese
Ea Genovese
Gastrointestinal tract perforations can occur for various causes such as peptic ulcer, inflammatory disease, blunt or penetrating trauma, iatrogenic factors, foreign body or a neoplasm that require an early recognition and, often, a surgical treatment.Ultrasonography could be useful as an initial diagnostic test to determine, in various cases the presence and, sometimes, the cause of the pneumoperitoneum.The main sonographic sign of perforation is free intraperitoneal air, resulting in an increased echogenicity of a peritoneal stripe associated with multiple reflection artifacts and characteristic comet-tail appearance.It is best detected using linear probes in the right upper quadrant between the anterior abdominal wall, in the prehepatic space.Direct sign of perforation may be detectable, particularly if they are associated with other sonographic abnormalities, called indirect signs, like thickened bowel loop and air bubbles in ascitic fluid or in a localized fluid collection, bowel or gallbladder thickened wall associated with decreased bowel motility or ileus.Neverthless, this exam has its own pitfalls. It is strongly operator-dependant; some machines have low-quality images that may not able to detect intraperitoneal free air; furthermore, some patients may be less cooperative to allow for scanning of different regions; sonography is also difficult in obese patients and with those having subcutaneous emphysema. Although CT has more accuracy in the detection of the site of perforation, ultrasound may be particularly useful also in patient groups where radiation burden should be limited notably children and pregnant women.

1 January 2013 in BMC Surgery
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Journal Article
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ARAlfonso Reginelli
Alfonso Reginelli
FIFrancesca Iacobellis
Francesca Iacobellis
DBDaniela Berritto
Daniela Berritto
GGGiuliano Gagliardi
Giuliano Gagliardi
Graziella Di GreziaGraziella Di Grezia
Graziella Di Grezia
ROBERTO GRASSIROBERTO GRASSI
ROBERTO GRASSI
Intestinal ischemia is an abdominal emergency that accounts for approximately 2% of gastrointestinal illnesses. It represents a complex of diseases caused by impaired blood perfusion to the small and/or large bowel including acute arterial mesenteric ischemia (AAMI), acute venous mesenteric ischemia (AVMI), non occlusive mesenteric ischemia (NOMI), ischemia/reperfusion injury (I/R), ischemic colitis (IC). In this study different study methods (US, CT) will be correlated in the detection of mesenteric ischemia imaging findings due to various etiologies. Basing on our institutions experience, 163 cases of mesenteric ischemia/infarction from various cases, investigated with CT and undergone surgical treatment were retrospectively evaluated, in particular trought the following findings: presence/absence of arterial/venous obstruction, bowel wall thickness and enhancement, presence/absence of spastic reflex ileus, hypotonic reflex ileus or paralitic ileus, mural and/or portal/mesenteric pneumatosis, abdominal free fluid, parenchymal ischemia/infarction (liver, kidney, spleen). To make an early diagnosis useful to ensure a correct therapeutic approach, it is very important to differentiate between occlusive (arterial, venous) and non occlusive causes (NOMI). The typical findings of each forms of mesenteric ischemia are explained in the text. The radiological findings of mesenteric ischemia have different course in case of different etiology. In venous etiology the progression of damage results faster than arterial even if the symptomatology is less acute; bowel wall thickening is an early finding and easy to detect, simplifying the diagnosis. In arterial etiology the damage progression is slower than in venous ischemia, bowel wall thinning is typical but difficult to recognize so diagnosis may be hard. In the NOMI before/without reperfusion the ischemic damage is similar to AAMI with additional involvement of large bowel parenchymatous organs. In reperfusion after NOMI and after AAMI the CT and surgical findings are similar to those of AVMI, and the injured bowel results quite easy to identify. The prompt recognition of each condition is essential to ensure a successful treatment.

31 March 2020 in Medical Oncology
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VNValerio Nardone
Valerio Nardone
ARAlfonso Reginelli
Alfonso Reginelli
CGCesare Guida
Cesare Guida
MBMaria Paola Belfiore
Maria Paola Belfiore
MBMichelangelo Biondi
Michelangelo Biondi
RGRoberto Grassi
Roberto Grassi