Introduction: We designed a follow‐up study of frontline health workers at COVID‐19 patient care, within the same working conditions, to assess the influence of their general characteristics and pre‐existing anxiety/depression/dissociative symptoms and resilience on the development of symptoms of post‐traumatic stress disorder (PTSD), while monitoring their quality of sleep, depersonalization/derealization symptoms, acute stress, state anxiety, and burnout.Methods: In a Hospital reconfigured to address the surge of patients with COVID‐19, 204 frontline health workers accepted to participate. They completed validated questionnaires to assess mental health: before, during, and after the peak of inpatient admissions. After each evaluation, a psychiatrist reviewed the questionnaires, using the accepted criteria for each instrument. Correlations were assessed using multivariable and multivariate analyses, with a significance level of .05.Results: Compared to men, women reporting pre‐existing anxiety were more prone to acute stress; and younger age was related to both pre‐existent common psychological symptoms and less resilience. Overall the evaluations, sleep quality was bad on the majority of participants, with an increase during the epidemic crisis, while persistent burnout had influence on state anxiety, acute stress, and symptoms of depersonalization/derealization. PTSD symptoms were related to pre‐existent anxiety/depression and dissociative symptoms, as well as to acute stress and acute anxiety, and negatively related to resilience.Conclusions: Pre‐existent anxiety/depression, dissociative symptoms, and coexisting acute anxiety and acute stress contribute to PTSD symptoms. During an infectious outbreak, psychological screening could provide valuable information to prevent or mitigate against adverse psychological reactions by frontline healthcare workers caring for patients.

Objective: To assess the influence of BMI group (lean/overweight/obese) and gender on the postural sway of adults and adolescents during quiet upright stance. Methods: 90 women and 90 men, aged 12 to 67 years old, accepted to participate. The center of pressure during quiet upright stance was recorded using a force platform, during 4 conditions (eyes open/closed on hard/soft surface). Statistical analysis was performed using multivariate analysis of covariance. Results: During recordings on hard surface, closing the eyes produced a larger increase of sway on obese subjects than on lean and overweight subjects, with a larger increase on the length and the area of sway. Although gender differences were found during the four sensory conditions, no interaction was observed between the BMI group and the gender. These results were not related to the age of the subjects. Conclusion: Compared to non-obese subjects, the postural stability of obese subjects may be more vulnerable when vision is not available, with no influence of the gender.

L’obiettivo di questo studio è stato quello di valutare la funzione utricolare e la funzione dei canali semicircolari laterali in pazienti con diabete mellito di tipo 2, con o senza cadute, afferenti all’assistenza sanitaria di base. Sono stati arruolati 101 pazienti con diabete mellito di tipo 2 (26 con storia di cadute, 75 senza), di età compresa tra 34 e 84 anni, e 51 volontari sani di età compresa tra 40 e 83 anni, i quali hanno negato vertigini, capogiri, instabilità, ipoacusia o disordini neurologici. Nessuno di loro era in cerca di cure per deficit sensoriali o dell’equilibrio. Dopo aver effettuato una valutazione clinica e dopo aver indagato i sintomi relativi alla sfera dell’equilibrio con l’ausilio di un questionario standardizzato, la funzione dei canali semicircolari laterali è stata studiata con il test sinusoidale alle velocità di 0,16 Hz e 1,28 Hz (il picco della velocità è stato fissato a 60°/s); la funzione otolitica, invece, è stata studiata con la verticale visiva soggettiva, determinata sia tramite test statico sia tramite test dinamico, durante centrifugazione unilaterale (300°/s a 3.5 cm); è stata eseguita inoltre la posturografia statica, su pedana soffice e dura, ad occhi aperti e chiusi. Confrontando i risultati ottenuti nei pazienti diabetici e in quelli sani, i pazienti diabetici hanno mostrato risposte inferiori alla centrifugazione unilaterale, ma risposte simili alla stimolazione dei canali semicircolari laterali, indipendentemente da età, neuropatie periferiche o storia di cadute (ANCoVA p < 0.05). I pazienti con storia di cadute, rispetto a quelli senza storia di cadute, erano per lo più donne e hanno raggiunto più facilmente un punteggio maggiore o pari a 4 al questionario sui sintomi relativi al senso dell’equilibrio; tuttavia i due gruppi hanno mostrato simili età, indice di massa corporea e neuropatia periferica. Nei pazienti con diabete di tipo 2, afferenti all’assistenza sanitaria di base e non in cerca di cure per deficit sensoriali o dell’equilibrio, la funzione utricolare potrebbe essere alterata, anche in assenza di disfunzione dei canali semicircolari laterali o di storia di cadute.

The COVID-19 pandemic has provoked generalized uncertainty around the world, with health workers experiencing anxiety, depression, burnout, insomnia, and stress. Although the effects of the pandemic on mental health may change as it evolves, the majority of reports have been web-based, cross-sectional studies. We performed a study assessing acute stress in frontline health workers during two consecutive epidemic waves. After screening for trait anxiety/depression and dissociative experiences, we evaluated changes in acute stress, considering resilience, state anxiety, burnout, depersonalization/derealization symptoms, and quality of sleep as cofactors. During the first epidemic wave (April 2020), health workers reported acute stress related to COVID-19, which was related to state anxiety. After the first epidemic wave, acute stress decreased, with no increase during the second epidemic wave (December 2020), and further decreased when vaccination started. During the follow-up (April 2020 to February 2021), the acute stress score was related to bad quality of sleep. However, acute stress, state anxiety, and burnout were all related to trait anxiety/depression, while the resilience score was invariant through time. Overall, the results emphasize the relevance of mental health screening before, during, and after an epidemic wave of infections, in order to enable coping during successive sanitary crises.

BACKGROUND: Feelings of unreality have been provoked in healthy subjects undergoing stimulation of the semicircular canals, but no studies have assessed the influence of otoliths stimulation on depersonalization/derealization (DD) symptoms. OBJECTIVE