Marcel Winkelmann

Dr. Marcel Winkelmann

Hannover Medical School
orcid

Research Focus & Metrics

Academic Career Length

13Years (2014-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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22 August 2020 in Journal of Clinical Medicine
Verified
Journal Article
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CMChristian Macke
Christian Macke
FGFelix Gralla
Felix Gralla
MWMarcel Winkelmann
Marcel Winkelmann
JCJan-Dierk Clausen
Jan-Dierk Clausen
MHMarco Haertlé
Marco Haertlé
MOMohamed Omar
Mohamed Omar
Endotracheal intubation (ETI) with direct view laryngoscopy (DL) is the gold standard for airway management. Videolaryngoscopy (VL) can improve glottis visualization, thus facilitating ETI. The aim of this monocentric, randomized, prospective study on a physician staffed German air ambulance is to compare DL and VL for ETI in terms of number of attempts and time as well as visualization of the glottis in a prehospital setting in a physician-based rescue system in adult patients. A power analysis was performed à priori. We used consecutive on-scene randomization with a sealed envelope system for the DL and VL-group. Successful ETI with first pass success was significantly more frequent with VL than DL and three seconds faster. The percentage of glottis opening and the Cormack & Lehane classification were significantly better with VL than DL. Regarding improved first pass success in ETI with the VL, we would recommend the use of VL for prehospital airway management in physician-based rescue systems.

6 March 2021 in Archives of orthopaedic and trauma surgery
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Journal Article
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MÖMarcus Örgel
Marcus Örgel
MPMaximilian Petri
Maximilian Petri
ARAlexander Ranker
Alexander Ranker
NWNils Wirries
Nils Wirries
TGTilman Graulich
Tilman Graulich
HAHorst-Heinrich Aschoff
Horst-Heinrich Aschoff
Introduction: Transcutaneous osseointegrated prosthetic systems (TOPS) are anchored prosthetic systems for major limb loss. Sometimes TOPS patients suffer from periprosthetic fractures. The aim of this study was to analyze the management and outcomes of periprosthetic fractures in patients with TOPS and to introduce a novel classification system for this entity. Material/methods: Since 2010, 140 patients were treated with TOPS after transfemoral amputation in two centers in Germany. Fifteen patients sustained periprosthetic fractures, with five intra- and ten postoperative fractures. The outcome was analyzed by Prosthesis Mobility Questionnaire (PMQ), K-level and prosthesis wear time per day. A subgroup analysis for the body mass index (BMI) was performed. Results: All postoperative fractures were treated with implant-retaining osteosynthesis. Fourteen fractures healed without complications after a mean of 3 months. One postoperative fracture developed a clinically asymptomatic firm non-union. No Endo-Fixstem had to be removed. For the fracture and control group, a significant increase of the PMQ (p < 0.001) and K-level (p < 0.001) was observed after TOPS treatment compared to the preoperative baseline. Furthermore, the subgroup analysis showed a significant increase of the PMQ and K-level for both normal weight (p = 0.002) and overweight patients (p < 0.001). Of interest, overweight patients even showed a significantly higher increase in scores compared to normal weight patients, regardless of periprosthetic fracture. Conclusion: Periprosthetic fractures do not necessarily worsen outcomes of TOPS treatment. Proper classification and standardized appropriate treatment strategies according to fracture morphology are paramount for reliably good outcomes. We recommend to not remove or exchange the implant (Endo-Fixstem) even if it is assembly. Higher BMI did not have an impact onto rehabilitation success after TOPS to major limb loss of the lower extremity.

30 October 2017 in European Journal of Medical Research
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Journal Article
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LFLisa Falkenberg
Lisa Falkenberg
CZChristian Zeckey
Christian Zeckey
PMPhilipp Mommsen
Philipp Mommsen
MWMarcel Winkelmann
Marcel Winkelmann
BZBoris A. Zelle
Boris A. Zelle
CPChristian Probst
Christian Probst
Physical impairment is well-known to last for many years after a severe injury, and there is a high impact on the quality of the survivor’s life. The purpose of this study was to examine if this is also true for psychological impairment with symptoms of posttraumatic stress disorder or depression after polytrauma. Retrospective cohort outcome study. Level I trauma centre. 637 polytrauma trauma patients who were treated at our Level I trauma centre between 1973 and 1990. Minimum follow-up was 10 years after the injury. Patients were asked to fill in a questionnaire, including parts of the Posttraumatic Stress Diagnostic Scale, the Impact of Event Scale-Revised and the German Hospital Anxiety and Depression Scale, to evaluate mental health. Clinical outcome was assessed before by standardised scores. Three hundred and twenty-four questionnaires were evaluated. One hundred and forty-nine (45.9%) patients presented with symptoms of mental impairment. Quality of life was significantly higher in the mentally healthy group, while the impaired group achieved a lower rehabilitation status. Mental impairment can be found in multiple trauma victims, even after 10 years or more. Treating physicians should not only focus on early physical rehabilitation but also focus on early mental rehabilitation to prevent long-term problems in both physical and mental disability.

1 July 2016 in Air Medical Journal
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Journal Article
Closed access
MWMarcel Winkelmann
Marcel Winkelmann
LFLars Friedrich
Lars Friedrich
CSChristian Schröter
Christian Schröter
AFAndreas Flemming
Andreas Flemming
HEHendrik Eismann
Hendrik Eismann
CZChristian Zeckey
Christian Zeckey

28 May 2019 in SICOT-J
Verified
Journal Article
Open access
MWMarcel Winkelmann
Marcel Winkelmann
ABAda Luise Butz
Ada Luise Butz
JCJan-Dierk Clausen
Jan-Dierk Clausen
RBRichard David Blossey
Richard David Blossey
CZChristian Zeckey
Christian Zeckey
PMPhilipp Mommsen
Philipp Mommsen
Introduction: Reliable diagnosis of shock in multiply injured patients is still challenging in emergency care. Point-of-care tests could have the potential to improve shock diagnosis. Therefore, this study aimed to analyze the impact of admission blood glucose on predicting shock in multiply injured patients.Methods: A retrospective cohort analysis of patients with an injury severity score (ISS) ≥ 16 who were treated in a level I trauma center from 01/2005 to 12/2014 was performed. Shock was defined by systolic blood pressure ≤ 90 mmHg and/or shock index ≥ 0.9 at admission. Laboratory shock parameters including glucose were measured simultaneously. Receiver-operating-characteristic (ROC) analysis and multivariate logistic regression analysis was performed.Results: Seven hundred and seventy-two patients were analyzed of whom 93 patients (12.0%) died. Two hundred and fifty-nine patients (33.5%) were in shock at admission. Mortality was increased if shock was present at admission (18.1% vs. 9.0%,p < 0.001). Mean glucose was 9.6 ± 4.0 mmol/L if shock was present compared to 8.0 ± 3.0 mmol/L (p < 0.001). Admission glucose positively correlated with shock (Spearman rho = 0.2,p < 0.001). Glucose showed an AUC of 0.62 (95% CI [0.58–0.66],p < 0.001) with an optimal cut off value of 11.5 mmol/L. Patients with admission glucose of > 11.5 mmol/L had a 2.2-fold risk of shock (95% CI [1.4–3.4],p = 0.001). Admission blood glucose of > 11.5 mmol/L positively correlated with mortality too (Spearman rho = 0.65,p < 0.001). Patients had a 2.5-fold risk of dying (95% CI [1.3–4.8],p = 0.004).Discussion: Admission blood glucose was proven as an independent indicator of shock and mortality and, therefore, might help to identify multiply injured patients at particular risk.

1 June 2016 in Orthopaedics & Traumatology: Surgery & Research
Verified
Journal Article
Closed access
MWMarcel Winkelmann
Marcel Winkelmann
JSJ.-N. Sorrentino
J.-N. Sorrentino
MKM. Klein
M. Klein
CMC. Macke
C. Macke
PMP. Mommsen
P. Mommsen
CZC. Zeckey
C. Zeckey