Stefan Bräse

Dr. Stefan Bräse

Karlsruhe Institute of Technology, Karlsruhe, Baden-Württemberg, Germany
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Research Focus & Metrics

Academic Career Length

35Years (1992-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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15 August 2005 in Angewandte Chemie International Edition
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SBStefan Bräse
Stefan Bräse
CGCarmen Gil
Carmen Gil
KKKerstin Knepper
Kerstin Knepper
VZViktor Zimmermann
Viktor Zimmermann

18 January 2021 in Advanced Materials
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GHGloria Hong
Gloria Hong
XGXuemin Gan
Xuemin Gan
CLCéline Leonhardt
Céline Leonhardt
ZZZhen Zhang
Zhen Zhang
JSJasmin Seibert
Jasmin Seibert
SBStefan Bräse
Stefan Bräse
Organic light‐emitting diodes (OLEDs) have come a long way ever since their first introduction in 1987 at Eastman Kodak. Today, OLEDs are especially valued in the display and lighting industry for their promising features. As one of the research fields that equally inspires and drives development in academia and industry, OLED device technology has continuously evolved over more than 30 years. OLED devices have come forward based on three generations of emitter materials relying on fluorescence (first generation), phosphorescence (second generation), and thermally activated delayed fluorescence (third generation). Furthermore, research in academia and industry toward the fourth generation of OLEDs is in progress. Excerpts from the history of green, orange‐red, and blue OLED emitter development on the side of academia and milestones achieved by key players in the industry are included in this report.

2 August 1999 in Angewandte Chemie International Edition
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KNK. C. Nicolaou
K. C. Nicolaou
CBChristopher Boddy
Christopher Boddy
SBStefan Bräse
Stefan Bräse
NWNicolas Winssinger
Nicolas Winssinger

5 October 2010 in Chemistry of Materials
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Journal Article
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WLWeigang Lu
Weigang Lu
DYDaqiang Yuan
Daqiang Yuan
DZDan Zhao
Dan Zhao
CSChristine Inge Schilling
Christine Inge Schilling
OPOliver Plietzsch
Oliver Plietzsch
HZHong-Cai Zhou
Hong-Cai Zhou

17 June 2009 in Chemical Reviews
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Journal Article
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SBStefan Bräse
Stefan Bräse
AEArantxa Encinas
Arantxa Encinas
JKJulia Keck
Julia Keck
CNCarl F. Nising
Carl F. Nising

12 February 2020 in Chemical Science
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AFAngelo Frei
Angelo Frei
JZJohannes Zuegg
Johannes Zuegg
AEAlysha G. Elliott
Alysha G. Elliott
MBMurray Baker
Murray Baker
SBStefan Bräse
Stefan Bräse
Mark BlaskovichMark Blaskovich
Mark Blaskovich
There is a dire need for new antimicrobial compounds to combat the growing threat of widespread antibiotic resistance. With a currently very scarce drug pipeline, consisting mostly of derivatives of known antibiotics, new classes of antibiotics are urgently required. Metal complexes are currently in clinical development for the treatment of cancer, malaria and neurodegenerative diseases. However, only little attention has been paid to their application as potential antimicrobial compounds. We report the evaluation of 906 metal-containing compounds that have been screened by the Community for Open Antimicrobial Drug Discovery (CO-ADD) for antimicrobial activity. Metal-bearing compounds display a significantly higher hit-rate (9.9%) when compared to the purely organic molecules (0.87%) in the CO-ADD database. Out of 906 compounds, 88 show activity against at least one of the tested strains, including fungi, while not displaying any cytotoxicity against mammalian cell lines or haemolytic properties. Herein, we highlight the structures of the 30 compounds with activity against Gram-positive and/or Gram-negative bacteria containing Mn, Co, Zn, Ru, Ag, Eu, Ir and Pt, with activities down to the nanomolar range against methicillin resistant S. aureus (MRSA). 23 of these complexes have not been reported for their antimicrobial properties before. This work reveals the vast diversity that metal-containing compounds can bring to antimicrobial research. It is important to raise awareness of these types of compounds for the design of truly novel antibiotics with potential for combatting antimicrobial resistance.