Online news reading has become a widely popular way to read news articles from news sources around the globe. With the enormous amount of news articles available, users are easily overwhelmed by information of little interest to them. News recommender systems help users manage this flood by recommending articles based on user interests rather than presenting articles in order of their occurrence. We present our research on developing personalized news recommendation system with the help of a popular micro-blogging service, “Twitter.” News articles are ranked based on the popularity of the article identified from Twitter’s public timeline. In addition, users construct profiles based on their interests and news articles are also ranked based on their match to the user profile. By integrating these two approaches, we present a hybrid news recommendation model that recommends interesting news articles to the user based on their popularity as well as their relevance to the user profile.

This manuscript describes the development of a resources module that is part of a learning platform named ‘NIGMS Sandbox for Cloud-based Learning’ https://github.com/NIGMS/NIGMS-Sandbox. The overall genesis of the Sandbox is described in the editorial NIGMS Sandbox at the beginning of this Supplement. This module delivers learning materials on implementing deep learning algorithms for biomedical image data in an interactive format that uses appropriate cloud resources for data access and analyses. Biomedical-related datasets are widely used in both research and clinical settings, but the ability for professionally trained clinicians and researchers to interpret datasets becomes difficult as the size and breadth of these datasets increases. Artificial intelligence, and specifically deep learning neural networks, have recently become an important tool in novel biomedical research. However, use is limited due to their computational requirements and confusion regarding different neural network architectures. The goal of this learning module is to introduce types of deep learning neural networks and cover practices that are commonly used in biomedical research. This module is subdivided into four submodules that cover classification, augmentation, segmentation and regression. Each complementary submodule was written on the Google Cloud Platform and contains detailed code and explanations, as well as quizzes and challenges to facilitate user training. Overall, the goal of this learning module is to enable users to identify and integrate the correct type of neural network with their data while highlighting the ease-of-use of cloud computing for implementing neural networks. This manuscript describes the development of a resource module that is part of a learning platform named ``NIGMS Sandbox for Cloud-based Learning'' https://github.com/NIGMS/NIGMS-Sandbox. The overall genesis of the Sandbox is described in the editorial NIGMS Sandbox [1] at the beginning of this Supplement. This module delivers learning materials on the analysis of bulk and single-cell ATAC-seq data in an interactive format that uses appropriate cloud resources for data access and analyses.

Text classifiers automatically classify documents into appropriate concepts for different applications. Most classification approaches use flat classifiers that treat each concept as independent, even when the concept space is hierarchically structured. In contrast, hierarchical text classification exploits the structural relationships between the concepts. In this article, we explore the effectiveness of hierarchical classification for a large concept hierarchy. Since the quality of the classification is dependent on the quality and quantity of the training data, we evaluate the use of documents selected from subconcepts to address the sparseness of training data for the top-level classifiers and the use of document relationships to identify the most representative training documents. By selecting training documents using structural and similarity relationships, we achieve a statistically significant improvement of 39.8% (from 54.5–76.2%) in the accuracy of the hierarchical classifier over that of the flat classifier for a large, three-level concept hierarchy.

Recommender systems can utilize Linked Open Data (LOD) to overcome some challenges, such as the item cold start problem, as well as the problem of explaining the recommendation. There are several techniques in exploiting LOD in recommender systems; one approach, called Linked Data Semantic Distance (LDSD), considers nearby resources to be recommended by calculating a semantic distance between resources. The LDSD approach, however, has some drawbacks such as its inability to measure the semantic distance resources that are not directly linked to each other. In this paper, we first propose another variation of the LDSD approach, called wtLDSD, by extending indirect distance calculations to include the effect of multiple links of differing properties within LOD, while prioritizing link properties. Next, we introduce an approach that broadens the coverage of LDSD-based approaches beyond resources that are more than two links apart. Our experimental results show that approaches we propose improve the accuracy of the LOD-based recommendations over our baselines. Furthermore, the results show that the propagation of semantic distance calculation to reflect resources further away in the LOD graph extends the coverage of LOD-based recommender systems.

Word vector representations open up new opportunities to extract useful information from unstructured text. Defining a word as a vector made it easy for the machine learning algorithms to understand a text and extract information from. Word vector representations have been used in many applications such word synonyms, word analogy, syntactic parsing, and many others. GloVe, based on word contexts and matrix vectorization, is an effective vector-learning algorithm. It improves on previous vector-learning algorithms. However, the GloVe model fails to explicitly consider the order in which words appear within their contexts. In this paper, multiple methods of incorporating word order in GloVe word embeddings are proposed. Experimental results show that our Word Order Vector (WOVe) word embeddings approach outperforms unmodified GloVe on the natural language tasks of analogy completion and word similarity. WOVe with direct concatenation slightly outperformed GloVe on the word similarity task, increasing average rank by 2%. However, it greatly improved on the GloVe baseline on a word analogy task, achieving an average 36.34% improvement in accuracy.