Pedro Alexandrino Fernandes is an Associate Professor at the Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto. He received a degree in chemistry (1993) and obtained a Ph.D. (2000) at the University of Porto. He teaches courses for degrees in M.Sc. in Chemistry, Biochemistry, and Bioinformatics, mainly in quantum chemistry, computational biochemistry and drug discovery. In recent years, his research has focused on the relationship between enzyme flexibility, reaction rate, and computational enzyme evolution through rational enzyme engineering. Other research areas he works in include the energetics and dynamics of proteins; diffusion of small druglike molecules across biomembranes;  molecular dynamics free energy calculations in proteins; molecular docking; and drug discovery.